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  • Sundin, Anders,1954-Uppsala universitet,Radiologi (author)

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : Radiological, Nuclear Medicine & Hybrid Imaging.

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2017-03-30
  • S. Karger AG,2017
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-319611
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-319611URI
  • https://doi.org/10.1159/000471879DOI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Contrast-enhanced computed tomography (CT) of the neckthorax-abdomen and pelvis, including 3-phase examination of the liver, constitutes the basic imaging for primary neuroendocrine tumor (NET) diagnosis, staging, surveillance, and therapy monitoring. CT characterization of lymph nodes is difficult because of inadequate size criteria (short axis diameter), and bone metastases are often missed. Contrast-enhanced magnetic resonance imaging (MRI) including diffusion-weighted imaging is preferred for the examination of the liver, pancreas, brain and bone. MRI may miss small lung metastases. MRI is less well suited than CT for the examination of extended body areas because of the longer examination procedure. Ultrasonography (US) frequently provides the initial diagnosis of liver metastases and contrast-enhanced US is excellent to characterize liver lesions that remain equivocal on CT/MRI. US is the method of choice to guide the biopsy needle for the histopathological NET diagnosis. US cannot visualize thoracic NET lesions for which CTguided biopsy therefore is used. Endocopic US is the most sensitive method to diagnose pancreatic NETs, and additionally allows for biopsy. Intraoperative US facilitates lesion detection in the pancreas and liver. Somatostatin receptor imaging should be a part of the tumor staging, preoperative imaging and restaging, for which 68 Ga-DOTA-somatostatin analog PET/CT is recommended, which is vastly superior to somatostatin receptor scintigraphy, and facilitates the diagnosis of most types of NET lesions, for example lymph node metastases, bone metastases, liver metastases, peritoneal lesions, and primary small intestinal NETs. (18)FDG-PET/CT is better suited for G3 and high G2 NETs, which generally have higher glucose metabolism and less somatostatin receptor expression than low-grade NETs, and additionally provides prognostic information.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Arnold, RudolfPhilipps Univ, Dept Gastroenterol & Endocrino (author)
  • Baudin, EricGustave Roussy Canc Campus, Dept Endocrine Oncol & Nucl Med (author)
  • Cwikla, Jaroslaw BUniv Warmia & Mazury, Fac Med Sci, Dept Radiol (author)
  • Eriksson, BarbroUppsala universitet,Endokrin tumörbiologi(Swepub:uu)barberik (author)
  • Fanti, StefanoUniv Bologna, Policlin S Orsola, Dept Nucl Med (author)
  • Fazio, NicolaEuropean Inst Oncol, Unit Gastrointestinal Med Oncol & Neuroendocrine (author)
  • Giammarile, FrancescoUniv Lyon, Hosp Civils Lyon, Nucl Med Dept (author)
  • Hicks, Rodney JPeter MacCallum Canc Ctr, Canc Imaging (author)
  • Kjaer, AndreasRigshosp, Dept Clin Physiol Nucl Med & PET; Rigshosp, Cluster Mol Imaging; Univ Copenhagen (author)
  • Krenning, EricErasmus MC, Dept Nucl Med (author)
  • Kwekkeboom, DikErasmus MC, Dept Nucl Med (author)
  • Lombard-Bohas, CatherineHop Edouard Herriot, Hosp Civils Lyon, Inst Canc (author)
  • O'Connor, Juan MGastroenterol Hosp B Udaondo, Alexander Fleming Inst (author)
  • O'Toole, DermotUniv Dublin, St Jamess Hosp, Trinity Coll Dublin; St Vincents Univ Hosp (author)
  • Rockall, AndreaRoyal Marsden NHS Fdn Trust, Dept Radiol; Imperial Coll London (author)
  • Wiedenmann, BertramCharite Univ Med Berlin, Campus Charite Mitte, Dept Gastroenterol & Hepatol; Charite Univ Med Berlin, Campus Virchow Klinikum (author)
  • Valle, Juan WUniv Manchester, Christie NHS Fdn Trust, Inst Canc Sci (author)
  • Vullierme, Marie-PierreHop Beaujon, Serv Gastroenterol (author)
  • Uppsala universitetRadiologi (creator_code:org_t)

Related titles

  • In:Neuroendocrinology: S. Karger AG105:3, s. 212-2440028-38351423-0194

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