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Ovarian tissue cryo...
Ovarian tissue cryopreservation and transplantation among alternatives for fertility preservation in the Nordic countries - compilation of 20 years of multicenter experience
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- Rodriguez-Wallberg, Kenny A. (författare)
- Karolinska Institutet
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- Tanbo, Tom (författare)
- Department of Gynecology, Oslo University Hospital, Oslo, Norway,Rigshosp University Hospital, Denmark,Copenhagen University Hospital
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- Tinkanen, Helena (författare)
- Oslo Univ Hosp, Dept Gynecol, Oslo, Norway.;Tampere Univ Hosp, Tampere, Finland.,Oslo University Hospital, Norway; Tampere University Hospital, Finland
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- Thurin-Kjellberg, Ann (författare)
- Sahlgrens Univ Hosp, Gothenburg, Sweden.,Sahlgrens University Hospital, Sweden
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- Nedstrand, Elisabeth (författare)
- Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Region Östergötland, Kvinnokliniken US,Linköping University Hospital
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- Kitlinski, Margareta Laczna (författare)
- Lund University,Lunds universitet,Obstetrisk, gynekologisk och prenatal ultraljudsdiagnostik,Forskargrupper vid Lunds universitet,Obstetric, Gynaecological and Prenatal Ultrasound Research,Lund University Research Groups,Skåne University Hospital
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- Macklon, Kirsten T. (författare)
- Rigshosp Univ Hosp, Copenhagen, Denmark.
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- Ernst, Erik (författare)
- Aarhus Univ Hosp, Aarhus, Denmark.,Aarhus University Hospital, Denmark
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- Fedder, Jens (författare)
- Odense Univ Hosp, Odense, Denmark.,Odense University Hospital, Denmark
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- Tiitinen, Aila (författare)
- Helsinki Univ Hosp, Helsinki, Finland.,Helsinki University Hospital, Finland,Helsinki University Central Hospital
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- Morin-Papunen, Laure (författare)
- Oulu Univ Hosp, Oulu, Finland.;Univ Oulu, Oulu, Finland.,Oulu University Hospital, Finland; University of Oulu, Finland
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- Einarsson, Snorri (författare)
- ART Medica, Reykjavik, Iceland.
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- Jokimaa, Varpu (författare)
- Turku Univ Hosp, Turku, Finland.,Turku University Hospital, Finland
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- Hippelainen, Maritta (författare)
- Kuopio Univ Hosp, Kuopio, Finland.,Kuopio University Hospital, Finland
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- Lood, Mikael (författare)
- Orebro Univ Hosp, Orebro, Sweden.,Örebro University Hospital, Sweden
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- Gudmundsson, Johannes (författare)
- Uppsala universitet,Obstetrik & gynekologi,University of Uppsala Hospital, Sweden
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- Olofsson, Jan I. (författare)
- Karolinska Institutet,Karolinska Institute
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- Andersen, Claus Yding (författare)
- Rigshosp Univ Hosp, Copenhagen, Denmark.;Univ Copenhagen, Reprod Biol Lab, Copenhagen, Denmark.,Rigshosp University Hospital, Denmark; University of Copenhagen, Denmark
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(creator_code:org_t)
- 2016-07-03
- 2016
- Engelska.
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : WILEY-BLACKWELL. - 0001-6349 .- 1600-0412. ; 95:9, s. 1015-1026
- Relaterad länk:
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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https://liu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Introduction. The aim of this study is to report the current status of ovarian tissue cryopreservation among alternatives for fertility preservation in the Nordic countries. Material and methods. A questionnaire was sent to 14 Nordic academic reproductive centers with established fertility preservation programs. It covered fertility preservation cases performed up to December 2014, standard procedures for ovarian tissue cryopreservation and oocyte cryopreservation and reproductive outcomes following ovarian tissue transplantation. Results. Among the Nordic countries, Denmark and Norway practice ovarian tissue cryopreservation as a clinical treatment (822 and 164 cases, respectively) and their programs are centralized. In Sweden (457 cases), ovarian tissue cryopreservation is practiced at five of six centers and in Finland at all five centers (145 cases). Nearly all considered ovarian tissue cryopreservation to be experimental. In Iceland, embryo cryopreservation is the only option for fertility preservation. Most centers use slow-freezing methods for ovarian tissue cryopreservation. Most patients selected for ovarian tissue cryopreservation were newly diagnosed with cancer and the tissue was predominantly retrieved laparoscopically by unilateral oophorectomy. Only minor complications were reported. In total, 46 women have undergone ovarian tissue transplantation aiming at recovering fertility, 17 healthy children have been born and several additional pregnancies are currently ongoing. Whenever patients' clinical condition is permissive, oocyte cryopreservation after hormonal stimulation is preferred for fertility preservation. Between 2012 and 2014, a smaller proportion of females have undergone fertility preservation in the Nordic centers, in comparison to males (1: 3). Conclusions. Overall, ovarian tissue cryopreservation was reported to be safe. Slow freezing methods are still preferred. Promising results of recovery of fertility have been reported in Nordic countries that have initiated ovarian tissue transplantation procedures.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
Nyckelord
- Cancer
- female
- fertility preservation
- oocytes
- ovarian tissue cryopreservation
- ovarian transplantation
- Cancer
- female
- fertility preservation
- oocytes
- ovarian tissue cryopreservation
- ovarian transplantation
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Rodriguez-Wallbe ...
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Tanbo, Tom
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Tinkanen, Helena
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Thurin-Kjellberg ...
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Nedstrand, Elisa ...
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Kitlinski, Marga ...
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Macklon, Kirsten ...
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Ernst, Erik
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Fedder, Jens
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Tiitinen, Aila
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Morin-Papunen, L ...
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Einarsson, Snorr ...
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Jokimaa, Varpu
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Hippelainen, Mar ...
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Lood, Mikael
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Gudmundsson, Joh ...
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Olofsson, Jan I.
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Andersen, Claus ...
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Acta Obstetricia ...
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Uppsala universitet
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Linköpings universitet
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Lunds universitet
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Karolinska Institutet