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Prognostic Utility ...
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McCord, JamesHenry Ford Hlth Syst, Henry Ford Heart & Vasc Inst, 2799 West Grand Blvd K-14, Detroit, MI 48202 USA.
(författare)
Prognostic Utility of a Modified HEART Score in Chest Pain Patients in the Emergency Department
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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LIPPINCOTT WILLIAMS & WILKINS,2017
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-320704
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-320704URI
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https://doi.org/10.1161/CIRCOUTCOMES.116.003101DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:135307392URI
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Språk:engelska
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Sammanfattning på:engelska
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Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Background-The TRAPID-AMI trial study ( High-Sensitivity Troponin-T Assay for Rapid Rule-Out of Acute Myocardial Infarction) evaluated high-sensitivity cardiac troponin-T ( hs-cTnT) in a 1-hour acute myocardial infarction ( AMI) exclusion algorithm. Our study objective was to evaluate the prognostic utility of a modified HEART score ( m-HS) within this trial. Methods and Results-Twelve centers evaluated 1282 patients in the emergency department for possible AMI from 2011 to 2013. Measurements of hs-cTnT ( 99th percentile, 14 ng/L) were performed at 0, 1, 2, and 4 to 14 hours. Evaluation for major adverse cardiac events ( MACEs) occurred at 30 days ( death or AMI). Low-risk patients had an m-HS <= 3 and had either hs-cTnT<14 ng/L over serial testing or had AMI excluded by the 1-hour protocol. By the 1-hour protocol, 777 ( 60%) patients had an AMI excluded. Of those 777 patients, 515 ( 66.3%) patients had an m-HS <= 3, with 1 ( 0.2%) patient having a MACE, and 262 ( 33.7%) patients had an m-HS <= 4, with 6 ( 2.3%) patients having MACEs ( P=0.007). Over 4 to 14 hours, 661 patients had a hs-cTnT<14 ng/L. Of those 661 patients, 413 ( 62.5%) patients had an m-HS <= 3, with 1 ( 0.2%) patient having a MACE, and 248 ( 37.5%) patients had an m-HS >= 4, with 5 ( 2.0%) patients having MACEs ( P=0.03). Conclusions-Serial testing of hs-cTnT over 1 hour along with application of an m-HS identified a low-risk population that might be able to be directly discharged from the emergency department.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Cabrera, RafaelHenry Ford Hlth Syst, Henry Ford Heart & Vasc Inst, 2799 West Grand Blvd K-14, Detroit, MI 48202 USA.
(författare)
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Lindahl, Bertil,1957-Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR)(Swepub:uu)belin227
(författare)
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Giannitsis, EvangelosUniv Heidelberg Hosp, Dept Internal Med Cardiol Angiol & Pulmonol 3, Heidelberg, Germany.
(författare)
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Evans, KaleighHenry Ford Hosp Hlth Syst, Dept Internal Med, Detroit, MI USA.
(författare)
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Nowak, RichardHenry Ford Hlth Syst, Dept Emergency Med, Detroit, MI USA.
(författare)
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Frisoli, TiberioHenry Ford Hlth Syst, Henry Ford Heart & Vasc Inst, 2799 West Grand Blvd K-14, Detroit, MI 48202 USA.
(författare)
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Body, RichardCent Manchester Univ Hosp NHS Fdn Trust, Manchester, Lancs, England.
(författare)
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Christ, MichaelParacelsus Med Univ, Gen Hosp, Dept Emergency & Crit Care Med, Nurnberg, Germany.
(författare)
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deFilippi, Christopher R.Inova Heart & Vasc Inst, Dept Med, Falls Church, VA USA.
(författare)
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Christenson, Robert H.Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA.
(författare)
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Jacobsen, GordonHenry Ford Hlth Syst, Dept Publ Hlth Sci, Detroit, MI USA.
(författare)
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Alquezar, AitorHosp Santa Creu & Sant Pau, Dept Emergency Med, Barcelona, Spain.
(författare)
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Panteghini, MauroUniv Milan, Sch Med, Dept Biomed & Clin Sci Luigi Sacco, Milan, Italy.
(författare)
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Melki, DinaKarolinska Univ Hosp, Dept Cardiol, Karolinska Inst, Dept Med, Stockholm, Sweden.
(författare)
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Plebani, MarioUniv Hosp Padova, Dept Lab Med, Padua, Italy.
(författare)
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Verschuren, FranckClin Univ St Luc, Brussels, Belgium.;Catholic Univ Louvain, Brussels, Belgium.
(författare)
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French, JohnLiverpool Hosp, Sydney, NSW, Australia.;Univ New South Wales, Sydney, NSW, Australia.
(författare)
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Bendig, GarnetRoche Diagnost Germany, Penzberg, Germany.
(författare)
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Weiser, SilviaRoche Diagnost Germany, Penzberg, Germany.
(författare)
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Mueller, ChristianUniv Basel Hosp, Cardiol & Cardiovasc Res Inst Basel, Basel, Switzerland.
(författare)
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Henry Ford Hlth Syst, Henry Ford Heart & Vasc Inst, 2799 West Grand Blvd K-14, Detroit, MI 48202 USA.Institutionen för medicinska vetenskaper
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Circulation. Cardiovascular Quality and Outcomes: LIPPINCOTT WILLIAMS & WILKINS10:21941-77131941-7705
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Till lärosätets databas
- Av författaren/redakt...
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McCord, James
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Cabrera, Rafael
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Lindahl, Bertil, ...
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Giannitsis, Evan ...
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Evans, Kaleigh
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Nowak, Richard
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visa fler...
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Frisoli, Tiberio
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Body, Richard
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Christ, Michael
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deFilippi, Chris ...
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Christenson, Rob ...
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Jacobsen, Gordon
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Alquezar, Aitor
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Panteghini, Maur ...
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Melki, Dina
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Plebani, Mario
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Verschuren, Fran ...
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French, John
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Bendig, Garnet
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Weiser, Silvia
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Mueller, Christi ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Circulation. Car ...
- Av lärosätet
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Uppsala universitet
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Karolinska Institutet