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Reproductive Patter...
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Armuand, GabrielaLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten
(author)
Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden : A Population-Based Matched-Cohort Study
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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AMER SOC CLINICAL ONCOLOGY,2017
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-325332
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-325332URI
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https://doi.org/10.1200/JCO.2016.71.0582DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-150347URI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Correction in: Journal of Clinical Oncology, 2018, vol. 36, issue 20, page 2131DOI: 10.1200/JCO.79.3265
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Purpose: To compare the probability of a first live birth, age at time of birth, and time between diagnosis/referent date and birth between childhood and adolescent cancer survivors and an age-matched comparison group.Materials and Methods: A total of 1,206 survivors was included in the study, together with 2,412 age-matched individuals from the general population. A Cox proportional hazards model was used to investigate first live birth after diagnosis/referent date. Data were stratified by sex, age at diagnosis, and diagnostic era (ie, diagnosis before 1988 v in 1988 or later).Results: Overall, the probability of having a first live birth (hazard ratio [HR]) was significantly lower; men had lower HRs than women (HR, 0.65 v 0.79). There were no significant differences in the probability of having a first live birth among women diagnosed during adolescence (HR, 0.89), but the HR was lower among women with childhood cancers (HR, 0.47). Among male survivors, the situation was the opposite; men diagnosed during adolescence had lower HRs than survivors of childhood cancer (HR, 0.56 v 0.70). Examination of the data from the two diagnostic eras (before 1988 and 1988 or later) shows that the HR increased among female survivors after 1988 (HR, 0.71 v 0.90) and decreased among male survivors (HR, 0.72 v 0.59). A shorter time had elapsed between diagnosis/referent date and the birth of a first child among both male and female survivors compared with controls. In addition, female survivors were younger at time of birth.Conclusion: The study demonstrates reduced probability of having a first live birth among cancer survivors diagnosed during childhood or adolescence; men were particularly vulnerable.
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Added entries (persons, corporate bodies, meetings, titles ...)
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Skoog-Svanberg, Agneta,1958-Uppsala universitet,Institutionen för kvinnors och barns hälsa,Uppsala University, Uppsala, Sweden(Swepub:uu)agssv172
(author)
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Bladh, MarieLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US(Swepub:liu)marbl97
(author)
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Sydsjö, GunillaLinköpings universitet,Avdelningen för barns och kvinnors hälsa,Medicinska fakulteten,Region Östergötland, Kvinnokliniken US(Swepub:liu)gunsy68
(author)
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Linköpings universitetAvdelningen för barns och kvinnors hälsa
(creator_code:org_t)
Related titles
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In:Journal of Clinical Oncology: AMER SOC CLINICAL ONCOLOGY35:14, s. 1577-15830732-183X1527-7755
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