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Questionnaire-Based...
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Kaluza, JoannaKarolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, Stockholm, Sweden.; Warsaw Univ Life Sci SGGW, Dept Human Nutr, Nutr Res Lab, 159C Nowoursynowska St, PL-02776 Warsaw, Poland.
(författare)
Questionnaire-Based Anti-Inflammatory Diet Index as a Predictor of Low-Grade Systemic Inflammation.
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
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Mary Ann Liebert Inc,2018
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:uu-337200
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-337200URI
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https://doi.org/10.1089/ars.2017.7330DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:137244168URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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There is accumulating evidence that diet may be associated with markers of inflammation. We have evaluated if an empirically developed questionnaire-based Anti-Inflammatory Diet Index (AIDI) may predict low-grade systemic chronic inflammation in a Nordic population. The AIDI was developed using a 123-item food frequency questionnaire among 3503 women (56-74 years old) with high-sensitivity C-reactive protein (hsCRP) plasma concentration <20 mg/L. Using Spearman correlations, we identified 20 foods (AIDI-20) statistically significantly related to hsCRP. The median (range) of AIDI-20 was 8 (0-17) scores, and the median concentration of hsCRP in the lowest versus the highest quintile of AIDI-20 (≤6 vs. ≥11 scores) varied by 80% (1.8 vs. 1.0 mg/L, respectively). In a multivariable-adjusted linear regression model, women in the highest quintile of AIDI-20 compared with those in the lowest had a 26% (95% confidence interval [CI] 18-33%; p-trend <0.001) lower hsCRP concentration; each 1-score increment in the AIDI-20 was associated with a 0.06 (95% CI 0.04-0.08) mg/L lower hsCRP. The observed association between the AIDI-20 and hsCRP was robust by all hsCRP levels and in subgroups defined by inflammatory-related factors. Our results lead to the hypothesis that the empirically developed questionnaire-based dietary anti-inflammatory index may predict low-grade systemic inflammation. Antioxid. Redox Signal. 28, 78-84.
Ämnesord och genrebeteckningar
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C-reactive protein
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anti-inflammatory index
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diet
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food
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inflammation
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Harris, HollyFred Hutchinson Canc Res Ctr, Program Epidemiol, Div Publ Hlth Sci, Seattle, WA 98104 USA
(författare)
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Melhus, HåkanUppsala universitet,Klinisk farmakogenomik och osteoporos(Swepub:uu)hakamelh
(författare)
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Michaëlsson, Karl,1959-Uppsala universitet,Ortopedi(Swepub:uu)karlmich
(författare)
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Wolk, AlicjaKarolinska Institutet,Uppsala universitet,Ortopedi,Karolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, Stockholm, Sweden(Swepub:uu)alwol516
(författare)
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Karolinska Inst, Inst Environm Med, Unit Nutr Epidemiol, Stockholm, Sweden.; Warsaw Univ Life Sci SGGW, Dept Human Nutr, Nutr Res Lab, 159C Nowoursynowska St, PL-02776 Warsaw, Poland.Fred Hutchinson Canc Res Ctr, Program Epidemiol, Div Publ Hlth Sci, Seattle, WA 98104 USA
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Antioxidants and Redox Signaling: Mary Ann Liebert Inc28:1, s. 78-841523-08641557-7716
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