Fruit and vegetable consumption and risk of COPD: a prospective cohort study of men.

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Kaluza, Joanna (författare)

Fruit and vegetable consumption and risk of COPD : a prospective cohort study of men.

Artikel/kapitelEngelska2017

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2017-02-22
BMJ,2017
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LIBRIS-ID:oai:DiVA.org:uu-337256
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-337256URI
https://doi.org/10.1136/thoraxjnl-2015-207851DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:135830473URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

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BACKGROUND: Antioxidants present in fruits and vegetables may protect the lung from oxidative damage and prevent COPD.AIMS: To determine the association between fruit and vegetable consumption and risk of COPD by smoking status in men.METHODS: The population-based prospective Cohort of Swedish Men included 44 335 men, aged 45-79 years, with no history of COPD at baseline. Fruit and vegetable consumption was assessed with a self-administered questionnaire.RESULTS: During a mean follow-up of 13.2 years, 1918 incident cases of COPD were ascertained. A strong inverse association between total fruit and vegetable consumption and COPD was observed in smokers but not in never-smokers (p-interaction=0.02). The age-standardised incidence rate per 100 000 person-years in the lowest quintile (<2 servings/day) of total fruit and vegetable consumption was 1166 in current smokers and 506 in ex-smokers; among those in the highest quintile (≥5.3 servings/day), 546 and 255 per 100 000 person-years, respectively. The multivariable HR of COPD comparing extreme quintiles of total fruit and vegetable consumption was 0.60 (95% CI 0.47 to 0.76, p-trend <0.0001) in current smokers and 0.66 (95% CI 0.51 to 0.85, p-trend=0.001) in ex-smokers. Each one serving per day increment in total fruit and vegetable consumption decreased risk of COPD significantly by 8% (95% CI 4% to 11%) in current smokers and by 4% (95% CI 0% to 7%) in ex-smokers.CONCLUSIONS: These results indicate that high consumption of fruits and vegetables is associated with reduced COPD incidence in both current and ex-smokers but not in never-smokers.

Ämnesord och genrebeteckningar

COPD epidemiology

Biuppslag (personer, institutioner, konferenser, titlar ...)

Larsson, Susanna CKarolinska Institutet,Uppsala universitet,Ortopedi(Swepub:uu)susla720 (författare)
Orsini, NicolaKarolinska Institutet (författare)
Linden, AndersKarolinska Institutet (författare)
Wolk, AlicjaKarolinska Institutet,Uppsala universitet,Ortopedi(Swepub:uu)alwol516 (författare)
Uppsala universitetOrtopedi (creator_code:org_t)

Sammanhörande titlar

Ingår i:Thorax: BMJ72:6, s. 500-5090040-63761468-3296

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Av författaren/redakt...: Kaluza, Joanna; Larsson, Susanna ...; Orsini, Nicola; Linden, Anders; Wolk, Alicja

Artiklar i publikationen: Thorax

Av lärosätet: Uppsala universitet; Karolinska Institutet

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