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  • Fielding, R. A.Tufts Univ, Nutr Exercise Physiol & Sarcopenia Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, 711 Washington St, Boston, MA 02111 USA. (författare)

Effect of structured physical activity and nutritional supplementation on physical function in mobility-limited older adults : Results from the VIVE2 randomized trial

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • 2017-06-03
  • Springer Science and Business Media LLC,2017
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-341661
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-341661URI
  • https://doi.org/10.1007/s12603-017-0936-xDOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:136986679URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:du-25159URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska &language:-1_t

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • The interactions between nutritional supplementation and physical activity on changes in physical function among older adults remain unclear. The primary objective of this study was to examine the impact of nutritional supplementation plus structured physical activity on 400M walk capacity in mobility-limited older adults across two sites (Boston, USA and Stockholm, Sweden). All subjects participated in a physical activity program (3x/week for 24 weeks), involving walking, strength, balance, and flexibility exercises. Subjects were randomized to a daily nutritional supplement (150kcal, 20g whey protein, 800 IU vitamin D) or placebo (30kcal, non-nutritive). Participants were recruited from urban communities at 2 field centers in Boston MA USA and Stockholm SWE. Mobility-limited (Short Physical Performance Battery (SPPB) ae9) and vitamin D insufficient (serum 25(OH) D 9 - 24 ng/ml) older adults were recruited for this study. Primary outcome was gait speed assessed by the 400M walk. Results: 149 subjects were randomized into the study (mean age=77.5 +/- 5.4; female=46.3%; mean SPPB= 7.9 +/- 1.2; mean 25(OH)D=18.7 +/- 6.4 ng/ml). Adherence across supplement and placebo groups was similar (86% and 88%, respectively), and was also similar across groups for the physical activity intervention (75% and 72%, respectively). Both groups demonstrated an improvement in gait speed with no significant difference between those who received the nutritional supplement compared to the placebo (0.071 and 0.108 m/s, respectively (p=0.06)). Similar effects in physical function were observed using the SPPB. Serum 25(OH)D increased in supplemented group compared to placebo 7.4 ng/ml versus 1.3 ng/ml respectively. Results suggest improved gait speed following physical activity program with no further improvement with added nutritional supplementation.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Travison, T. G.Karolinska Institutet (författare)
  • Kirn, D. R.Tufts Univ, Nutr Exercise Physiol & Sarcopenia Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, 711 Washington St, Boston, MA 02111 USA. (författare)
  • Koochek, A.Uppsala Univ, Dept Publ Hlth & Caring Sci, Clin Nutr & Metab, Uppsala, Sweden. (författare)
  • Reid, K. F.Tufts Univ, Nutr Exercise Physiol & Sarcopenia Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, 711 Washington St, Boston, MA 02111 USA. (författare)
  • von Berens, ÅsaUppsala universitet,Klinisk nutrition och metabolism(Swepub:uu)asavo144 (författare)
  • Zhu, H.Hebrew SeniorLife, Inst Aging Res, Boston, MA USA. (författare)
  • Folta, S. C.Tufts Univ, Friedman Sch Nutr Sci & Policy, 711 Washington St, Boston, MA 02111 USA. (författare)
  • Sacheck, J. M.Tufts Univ, Friedman Sch Nutr Sci & Policy, 711 Washington St, Boston, MA 02111 USA. (författare)
  • Nelson, M. E.Tufts Univ, Friedman Sch Nutr Sci & Policy, 711 Washington St, Boston, MA 02111 USA.;Univ New Hampshire, Sustainabil Inst, Durham, NH 03824 USA. (författare)
  • Liu, C. K.Tufts Univ, Nutr Exercise Physiol & Sarcopenia Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, 711 Washington St, Boston, MA 02111 USA.;Boston Univ, Sch Med, Sect Geriatr, Boston, MA 02118 USA. (författare)
  • Åberg, Anna CristinaHögskolan Dalarna,Uppsala universitet,Geriatrik,School of Education, Health and Society, Dalarna University, Sweden,Medicinsk vetenskap(Swepub:du)aab (författare)
  • Nydahl, Margaretha,1953-Uppsala universitet,Geriatrik,School of Education, Health and Society, Dalarna University, Sweden(Swepub:uu)mny24448 (författare)
  • Lilja, M.Karolinska Institutet (författare)
  • Gustafsson, T.Karolinska Inst, Dept Lab Med, Stockholm, Sweden. (författare)
  • Cederholm, Tommy E.Karolinska Institutet,Uppsala universitet,Klinisk nutrition och metabolism(Swepub:uu)tomce419 (författare)
  • Karolinska InstitutetTufts Univ, Nutr Exercise Physiol & Sarcopenia Lab, Jean Mayer USDA Human Nutr Res Ctr Aging, 711 Washington St, Boston, MA 02111 USA. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:The Journal of Nutrition, Health & Aging: Springer Science and Business Media LLC21:9, s. 936-9421279-77071760-4788

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