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New Blood Pressure-...
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Kraja, Aldi T.Umeå University,Umeå universitet,Enheten för biobanksforskning,Folkhälsan Research Centre, Finland; Department of Endocrinology, Helsinki University Central Hospital, Finland; Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Finland,Washington Univ, Sch Med, Div Stat Genom, Dept Genet, St Louis, MO 63108 USA.;Washington Univ, Sch Med, Ctr Genome Sci & Syst Biol, St Louis, MO 63108 USA.,Helsinki Univ Cent Hosp, Folkhalsan Res Ctr, Helsinki, Finland.;Helsinki Univ Cent Hosp, Dept Endocrinol, Helsinki, Finland.;Umea Univ, Dept Biobank Res, Umea, Sweden.;Univ Helsinki, Finnish Inst Mol Med, Helsinki, Finland.,Washington University in St. Louis
(author)
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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LIPPINCOTT WILLIAMS & WILKINS,2017
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-347269
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-347269URI
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https://doi.org/10.1161/CIRCGENETICS.117.001778DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-145177URI
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https://lup.lub.lu.se/record/e7eb9d03-e711-4984-b2bb-6aba379dcf96URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background - Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants (SNVs) associated with BP from meta-analyses of exome chip genotype data. An additional 100 variants yielded suggestive evidence of association.Methods and Results - Here, we augment the sample with 140886 European individuals from the UK Biobank, in whom 77 of the 100 suggestive SNVs were available for association analysis with systolic BP or diastolic BP or pulse pressure. We performed 2 meta-analyses, one in individuals of European, South Asian, African, and Hispanic descent (pan-ancestry, approximate to 475000), and the other in the subset of individuals of European descent (approximate to 423000). Twenty-one SNVs were genome-wide significant (P<5x10(-8) ) for BP, of which 4 are new BP loci: rs9678851 (missense, SLC4A1AP), rs7437940 (AFAP1), rs13303 (missense, STAB1), and rs1055144 (7p15.2). In addition, we identified a potentially independent novel BP-associated SNV, rs3416322 (missense, SYNPO2L) at a known locus, uncorrelated with the previously reported SNVs. Two SNVs are associated with expression levels of nearby genes, and SNVs at 3 loci are associated with other traits. One SNV with a minor allele frequency <0.01, (rs3025380 at DBH) was genome-wide significant.Conclusions - We report 4 novel loci associated with BP regulation, and 1 independent variant at an established BP locus. This analysis highlights several candidate genes with variation that alter protein function or gene expression for potential follow-up.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Cook, James P.Univ Liverpool, Dept Biostatist, Liverpool, Merseyside, England.,University of Liverpool
(author)
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Warren, Helen R.William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.,Univ Eastern Finland, Kuopio Res Inst Exercise Med, Kuopio, Finland.;Univ Eastern Finland, Dept Clin Physiol & Nucl Med, Kuopio, Finland.,Queen Mary University,University of Eastern Finland
(author)
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Surendran, PraveenMRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.,University of Cambridge
(author)
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Liu, ChunyuFramingham Heart Dis Epidemiol Study, Framingham, MA USA.;NHLBI, Populat Sci Branch, Div Intramural Res, Bldg 10, Bethesda, MD 20892 USA.,National Heart Lung and Blood Institute
(author)
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Evangelou, EvangelosImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Univ Ioannina, Med Sch, Dept Hyg & Epidemiol, Ioannina, Greece.,Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.,Steno Diabet Ctr, Gentofte, Denmark.,William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;MRC BHF Cardiovasc Epidemiol Ctr, Dept Haematol, Cambridge, England.,University of Ioannina,Imperial College London,University of Edinburgh,Steno Diabetes Center Copenhagen,University of Cambridge,Queen Mary University
(author)
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Manning, Alisa K.Massachusetts Gen Hosp, Ctr Genom Med, Boston, MA 02114 USA.;Hebrew SeniorLife, Dept Med, Boston, MA USA.,Boston University,Massachusetts General Hospital
(author)
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Grarup, NielsUniv Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, Fac Hlth & Med Sci, Copenhagen, Denmark.,University of Copenhagen
(author)
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Drenos, FotiosUniv Bristol, Sch Social & Community Med, Med Res Council Integrat Epidemiol Unit, Bristol, Avon, England.;UCL, Ctr Cardiovasc Genet, Inst Cardiovasc Sci, London, England.,University of Bristol,University College London
(author)
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Sim, XuelingUniv Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.;Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.,National University of Singapore,University of Michigan
(author)
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Smith, Albert VernonMRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.;Iceland Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.,Icelandic Heart Association,University of Iceland
(author)
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Amin, NajafErasmus MC, Dept Epidemiol, Genet Epidemiol Unit, Rotterdam, Netherlands.,Univ Dundee, Ninewells Hosp & Med Sch, Med Res Inst, Dundee, Scotland. Univ Split, Fac Med, Split, Croatia.,Erasmus University Medical Center,University of Dundee
(author)
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Blakemore, Alexandra I. F.Imperial Coll London, Sect Invest Med, Dept Med, London, England.;Brunel Univ, Dept Life Sci, London, England.,Imperial College London,Brunel University London
(author)
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Bork-Jensen, JetteUniv Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, Fac Hlth & Med Sci, Copenhagen, Denmark.,University of Copenhagen
(author)
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Brandslund, IvanLillebaelt Hosp, Dept Clin Biochem, Vejle, Denmark.;Univ Southern Denmark, Inst Reg Hlth Res, Odense, Denmark.,University of Southern Denmark,Lillebaelt Hospital
(author)
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Farmaki, Aliki-EleniHarokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens, Greece.,Harokopio University
(author)
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Fava, CristianoLund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups,University of Verona(Swepub:lu)endo-cfa
(author)
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Ferreira, TeresaUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.,Wellcome Trust Centre for Human Genetics
(author)
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Herzig, Karl-HeinzUniv Oulu, Res Unit Biomed, Oulu, Finland.;Univ Oulu, Bioctr Oulu, Oulu, Finland.;Med Res Ctr, Oulu, Finland.;Oulu Univ Hosp, Oulu, Finland.;Poznan Univ Med Sci, Dept Gastroenterol & Metab, Poznan, Poland.,University of Oulu,Oulu University Hospital,Poznan University of Medical Sciences
(author)
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Giri, AyushVanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37235 USA.,Vanderbilt University
(author)
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Giulianini, FrancoBrigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.,Brigham and Women's Hospital / Harvard Medical School
(author)
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Lind, LarsUppsala University,Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Univ N Carolina, Dept Genet, Chapel Hill, NC USA.,University of Texas,National Human Genome Research Institute,Vanderbilt University,University of Michigan,University of North Carolina(Swepub:uu)larslind
(author)
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Guo, XiuqingHarbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA.;Harbor UCLA Med Ctr, Dept Pediat, Torrance, CA 90509 USA.,University of California, Los Angeles
(author)
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Harris, Sarah E.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.
(author)
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Have, Christian T.Univ Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, Fac Hlth & Med Sci, Copenhagen, Denmark.,University of Copenhagen
(author)
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Havulinna, Aki S.Natl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.;Inst Mol Med Finland, Helsinki, Finland.,Institute for Molecular Medicine Finland (FIMM),Department of Social Services and Health Care, Jakobstad
(author)
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Zhang, HeUniv Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA.,University of Michigan
(author)
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Jorgensen, Marit E.Steno Diabet Ctr, Gentofte, Denmark.
(author)
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Karajamaki, AnneMariVaasa Cent Hosp, Dept Primary Hlth Care, Vaasa, Finland.;Vaasa Hlth Care Ctr, Diabet Ctr, Vaasa, Finland.
(author)
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Kooperberg, CharlesFred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA USA.,Fred Hutchinson Cancer Research Center
(author)
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Linneberg, AllanRes Ctr Prevent & Hlth, Copenhagen, Denmark.;Rigshosp, Dept Clin Expt Res, Glostrup, Denmark.,Research Centre for Prevention and Health,Copenhagen University Hospital
(author)
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Little, LouisWilliam Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.,NHGRI, Med Genom & Metab Genet Branch, NIH, Bethesda, MD 20892 USA.,Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37235 USA.,Univ Michigan, Dept Epidemiol, Sch Publ Hlth, Ann Arbor, MI 48109 USA.,Queen Mary University
(author)
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Liu, YongmeiWake Forest Baptist Med Ctr, Epidemiol & Prevent Ctr Genom & Personalized Med, Med Ctr Blvd, Winston Salem, NC USA.;Vanderbilt Univ, Sch Med, Div Epidemiol, Dept Med,Vanderbilt Ingram Canc Ctr,Vanderbilt Ep, Nashville, TN 37212 USA.,Wake Forest Baptist Medical Center
(author)
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Bonnycastle, Lori L.NHGRI, Med Genom & Metab Genet Branch, NIH, Bethesda, MD 20892 USA.
(author)
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Lu, YingchangIcahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.,Vanderbilt University,Icahn School of Medicine at Mount Sinai
(author)
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Magi, ReedikUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.,University of Tartu
(author)
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Mahajan, AnubhaUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.,Wellcome Trust Centre for Human Genetics
(author)
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Malerba, GiovanniUniv Verona, Dept Neurosci Biomed & Movement, Sect Biol & Genet, Verona, Italy.,University of Verona
(author)
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Marioni, Riccardo E.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Ctr Genom & Expt Med, Edinburgh, Midlothian, Scotland.
(author)
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Mei, HaoUniv Mississippi, Med Ctr, Dept Data Sci, Jackson, MS 39216 USA.,University of Mississippi Medical Center
(author)
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Menni, CristinaKings Coll London, Dept Twin Res & Genet Epidemiol, London, England.,King's College London
(author)
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Morrison, Alanna C.McGovern Med Sch, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA.;Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA.,University of Texas
(author)
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Padmanabhan, SandoshUniv Glasgow, British Heart Fdn, Inst Cardiovasc & Med Sci, Coll Med Vet & Life Sci,Glasgow Cardiovasc Res Ct, Glasgow, Lanark, Scotland.,University of Glasgow
(author)
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Palmas, WalterColumbia Univ, Dept Med, Med Ctr, New York, NY USA.,Columbia University
(author)
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Poveda, AlaitzLund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-azp
(author)
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Rauramaa, RainerUniv Eastern Finland, Kuopio Res Inst Exercise Med, Kuopio, Finland.;Univ Eastern Finland, Dept Clin Physiol & Nucl Med, Kuopio, Finland.,Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.,Imperial Coll London, Int Ctr Circulatory Hlth, London, England.,Aarhus Univ, Dept Publ Hlth, Aarhus, Denmark.;Danish Diabet Acad, Odense, Denmark.,Queen Mary University,Imperial College London,Danish Diabetes Academy,Aarhus University
(author)
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Rayner, Nigel WilliamUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Radcliffe Dept Med, Oxford, England.;Kuopio Univ Hosp, Kuopio, Finland.,University of Oxford,Wellcome Trust Centre for Human Genetics,Wellcome Trust Sanger Institute
(author)
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Riaz, MuhammadWellcome Trust Sanger Inst, Hinxton, England.;Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England.,Glenfield Hospital
(author)
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Rice, KenUniv Washington, Dept Biostat, Seattle, WA 98195 USA.
(author)
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Richard, Melissa A.McGovern Med Sch, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA.;McGovern Med Sch, Brown Fdn Inst Mol Med, Houston, TX 77030 USA.,University of Texas Health Science Center at Houston
(author)
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Smith, Jennifer A.Univ Michigan, Dept Epidemiol, Sch Publ Hlth, Ann Arbor, MI 48109 USA.,University of Michigan
(author)
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Southam, LorraineUniv Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Kuopio Univ Hosp, Kuopio, Finland.,Wellcome Trust Sanger Institute,Wellcome Trust Centre for Human Genetics
(author)
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Stancakova, AlenaUniv Eastern Finland, Kuopio, Finland.,University of Eastern Finland
(author)
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Stirrups, Kathleen E.William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;MRC BHF Cardiovasc Epidemiol Ctr, Dept Haematol, Cambridge, England.
(author)
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Tragante, ViniciusUniv Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands.,University Medical Center Utrecht
(author)
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Tuomi, TiinamaijaHelsinki Univ Cent Hosp, Folkhalsan Res Ctr, Helsinki, Finland.;Helsinki Univ Cent Hosp, Dept Endocrinol, Helsinki, Finland.;Umea Univ, Dept Biobank Res, Umea, Sweden.;Univ Helsinki, Finnish Inst Mol Med, Helsinki, Finland.
(author)
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Tzoulald, IoannaImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.;Univ Ioannina, Med Sch, Dept Hyg & Epidemiol, Ioannina, Greece.,University of Ioannina,Imperial College London
(author)
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Varga, Tibor V.Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,University of Eastern Finland(Swepub:lu)med-tv_
(author)
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Weiss, StefanUniv Med, Interfac Inst Genet & Funct Genom, Greifswald, Germany.;Ernst Moritz Arndt Univ Greifswald, Greifswald, Germany.;DZHK German Ctr Cardiovasc Res, Partner Site Greifswald, Berlin, Germany.,University of Greifswald,German Centre for Cardiovascular Research
(author)
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Yiorkas, Andrianos M.Imperial Coll London, Sect Invest Med, Dept Med, London, England.;Brunel Univ, Dept Life Sci, London, England.,Brunel University London,Imperial College London
(author)
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Young, RobinMRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.,University of Cambridge
(author)
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Zhang, WeihuaImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;London North West Healthcare NHS Trust, Dept Cardiol, Ealing Hosp, London, England.,Ealing Hospital,Imperial College London
(author)
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Barnes, Michael R.Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.
(author)
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Cabrera, Claudia P.William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.,Queen Mary University
(author)
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Gao, HeImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.,Imperial College London
(author)
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Boehnke, MichaelUniv Michigan, Dept Biostat, Ann Arbor, MI 48109 USA.;Univ Michigan, Ctr Stat Genet, Ann Arbor, MI 48109 USA.,University of Michigan
(author)
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Boerwinkle, EricMcGovern Med Sch, Human Genet Ctr, Sch Publ Hlth, Houston, TX USA.;Univ Texas Hlth Sci Ctr Houston, Houston, TX 77030 USA.;Baylor Coll Med, Human Genome Sequencing Ctr, Houston, TX 77030 USA.,Baylor College of Medicine,University of Texas
(author)
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Chambers, John C.Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;London North West Healthcare NHS Trust, Dept Cardiol, Ealing Hosp, London, England.;Imperial Coll Healthcare NHS Trust, London, England.,Imperial College London,Ealing Hospital
(author)
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Connell, John M.Univ Dundee, Ninewells Hosp & Med Sch, Dundee, Scotland.,University of Dundee,Queen Mary University
(author)
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Christensen, Cramer K.Lillebaelt Hosp, Med Dept, Vejle, Denmark.,Lillebaelt Hospital
(author)
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de Boer, Rudolf A.Univ Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.,University Medical Center Groningen
(author)
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Deary, Ian J.Univ Edinburgh, Ctr Cognit Ageing & Cognit Epidemiol, Edinburgh, Midlothian, Scotland.;Univ Edinburgh, Psychol, Edinburgh, Midlothian, Scotland.,University of Edinburgh
(author)
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Dedoussis, GeorgeHarokopio Univ, Sch Hlth Sci & Educ, Dept Nutr & Dietet, Athens, Greece.,Harokopio University
(author)
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Deloukas, PanosWilliam Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.,Queen Mary University
(author)
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Dominiczak, Anna F.Univ Glasgow, British Heart Fdn, Inst Cardiovasc & Med Sci, Coll Med Vet & Life Sci,Glasgow Cardiovasc Res Ct, Glasgow, Lanark, Scotland.,University of Glasgow
(author)
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Dorr, MarcusUniv Med, Interfac Inst Genet & Funct Genom, Greifswald, Germany.;Ernst Moritz Arndt Univ Greifswald, Greifswald, Germany.;Univ Med Greifswald, Dept Internal Med B Cardiol Intens Care Med Infec, Greifswald, Germany.,University Medicine Greifswald,University of Greifswald
(author)
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Joehanes, RobyFramingham Heart Dis Epidemiol Study, Framingham, MA USA.;NIH, Ctr Informat Technol, Math & Stat Comp Lab, Bldg 10, Bethesda, MD 20892 USA.;Hebrew SeniorLife, Inst Aging Res, Boston, MA USA.,National Institutes of Health, United States
(author)
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Edwards, Todd L.Vanderbilt Univ, Med Ctr, Vanderbilt Epidemiol Ctr, Inst Med & Publ Hlth, Nashville, TN 37235 USA.
(author)
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Esko, TonuUniv Tartu, Estonian Genome Ctr, Tartu, Estonia.,University of Tartu
(author)
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Fornage, MyriamMcGovern Med Sch, Brown Fdn Inst Mol Med, Houston, TX 77030 USA.,University of Texas Health Science Center at Houston
(author)
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Franceschini, NoraUniv N Carolina, Dept Epidemiol, Chapel Hill, NC USA.,University of North Carolina
(author)
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Franks, Paul W.Umeå University,Lund University,Lunds universitet,Umeå universitet,Medicin,Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, United States,Lund Univ, Dept Clin Sci, Genet & Mol Epidemiol Unit, Malmo, Sweden.;Harvard TH Chan Sch Publ Hlth, Dept Nutr, Boston, MA USA.;Umea Univ, Dept Publ Hlth & Clin Med, Umea, Sweden.,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-plf
(author)
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Gambaro, GiovanniUniv Cattolica Sacro Cuore, Dept Nephrol & Dialysis, Rome, Italy.,Univ Mississippi, Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA.,Catholic University of the Sacred Heart, Rome,University of Mississippi Medical Center
(author)
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Groop, LeifLund University,Lunds universitet,-lup-obsolete,Forskargrupper vid Lunds universitet,Genomik, diabetes och endokrinologi,LUDC (Lund University Diabetes Centre)-lup-obsolete,Lund University Research Groups,Genomics, Diabetes and Endocrinology,Institute for Molecular Medicine Finland (FIMM),University of Helsinki(Swepub:lu)endo-lgr
(author)
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Hallmans, GöranUmeå University,Umeå universitet,Enheten för biobanksforskning,Umea Univ, Dept Biobank Res, Umea, Sweden.(Swepub:umu)goha0001
(author)
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Hansen, TorbenUniv Copenhagen, Novo Nordisk Fdn Ctr Basic Metab Res, Fac Hlth & Med Sci, Copenhagen, Denmark.,University of Copenhagen
(author)
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Hayward, CarolineUniv Edinburgh, Inst Genet & Mol Med, Med Res Council Human Genet Unit, Edinburgh, Midlothian, Scotland.,University of Edinburgh
(author)
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Heikki, OksaTampere Univ Hosp, Tampere, Finland.,Tampere University Hospital
(author)
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Ingelsson, Erik,1975-Uppsala University,Uppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab,Stanford Univ, Dept Med, Sch Med, Div Cardiovasc Med, Stanford, CA 94305 USA,Stanford University(Swepub:uu)ering425
(author)
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Tuomilehto, JaakkoNatl Inst Hlth & Welf, Chron Dis Prevent Unit, Helsinki, Finland.;Dasman Diabet Inst, Kuwait, Kuwait.;King Abdulaziz Univ, Diabet Res Grp, Jeddah, Saudi Arabia.;Danube Univ Krems, Dept Neurosci & Prevent Med, Krems An Der Donau, Austria.,King Abdulaziz University,Finnish National Institute for Health and Welfare,Danube University Krems,Dasman Diabetes Institute
(author)
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Jarvelin, Marjo-RiittaImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.;Univ Oulu, Fac Med, Ctr Life Course Hlth Res, Oulu, Finland.,University of Oulu,Imperial College London
(author)
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Kardia, Sharon L. R.Univ Michigan, Dept Epidemiol, Sch Publ Hlth, Ann Arbor, MI 48109 USA.
(author)
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Karpe, FredrikUniv Oxford, Oxford Ctr Diabet Endocrinol & Metab, Radcliffe Dept Med, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.,University of Oxford
(author)
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Kooner, Jaspal S.London North West Healthcare NHS Trust, Dept Cardiol, Ealing Hosp, London, England.;Imperial Coll Healthcare NHS Trust, London, England.;Imperial Coll London, Natl Heart & Lung Inst, Hammersmith Hosp Campus, London, England.,Hammersmith Hospital,Ealing Hospital,Imperial College London
(author)
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Lakka, Timo A.Univ Eastern Finland, Kuopio Res Inst Exercise Med, Kuopio, Finland.;Univ Eastern Finland, Dept Clin Physiol & Nucl Med, Kuopio, Finland.;Univ Eastern Finland, Inst Biomed Physiol, Kuopio, Finland.,University of Eastern Finland
(author)
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Langenberg, ClaudiaUniv Cambridge, Inst Metab Sci, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England.,University of Cambridge
(author)
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Lind, LarsUppsala universitet,Molekylär epidemiologi,Science for Life Laboratory, SciLifeLab(Swepub:uu)larslind
(author)
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Loos, Ruth J. F.Icahn Sch Med Mt Sinai, Charles Bronfman Inst Personalized Med, New York, NY 10029 USA.,Icahn School of Medicine at Mount Sinai
(author)
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Laakso, MarkkuUniv Eastern Finland, Dept Med, Kuopio, Finland.,University of Eastern Finland
(author)
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McCarthy, Mark I.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Radcliffe Dept Med, Oxford, England.;Oxford Univ Hosp Trust, Oxford NIHR Biomed Res Ctr, Oxford, England.,Wellcome Trust Centre for Human Genetics,University of Oxford
(author)
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Melander, OlleLund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups(Swepub:lu)endo-ome
(author)
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Mohlke, Karen L.Univ N Carolina, Dept Genet, Chapel Hill, NC USA.
(author)
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Moris, Andrwe P.Univ Liverpool, Dept Biostatist, Liverpool, Merseyside, England.,University of Liverpool
(author)
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Palmer, Colin N. A.Univ Dundee, Ninewells Hosp & Med Sch, Med Res Inst, Dundee, Scotland. Univ Split, Fac Med, Split, Croatia.
(author)
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Pedersen, OlufUniversity of Copenhagen
(author)
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Polasek, OzrenUniversity of Split
(author)
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Poulter, Neil R.Imperial Coll London, Int Ctr Circulatory Hlth, London, England.
(author)
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Province, Michael A.Washington Univ, Sch Med, Div Stat Genom, Dept Genet, St Louis, MO 63108 USA.;Washington Univ, Sch Med, Ctr Genome Sci & Syst Biol, St Louis, MO 63108 USA.,Washington University in St. Louis
(author)
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Psaty, Bruce M.Univ Washington, Dept Med, Cardiovasc Hlth Res Unit, Seattle, WA USA.;Univ Washington, Dept Epidemiol & Hlth Serv, Seattle, WA 98195 USA.;Kaiser Permanente Washington Hlth Res Inst, Seattle, WA USA. Wake Forest Sch Med, Dept Biostat Sci, Div Publ Hlth Sci, Winston Salem, NC USA.,Kaiser Permanente Research Institute,University of Washington
(author)
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Ridker, Paul M.Hebrew SeniorLife, Dept Med, Boston, MA USA.;Harvard Med Sch, Boston, MA USA.;Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.,Brigham and Women's Hospital / Harvard Medical School,Boston University
(author)
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Rotter, Jerome I.Harbor UCLA Med Ctr, Inst Translat Genom & Populat Sci, Torrance, CA 90509 USA.;Harbor UCLA Med Ctr, Dept Pediat, Torrance, CA 90509 USA.,University of California, Los Angeles
(author)
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Rudan, IgorUniv Edinburgh, Usher Inst Populat Hlth Sci & Informat, Edinburgh, Midlothian, Scotland. Univ Edinburgh, Alzheimer Scotland Res Ctr, Edinburgh, Midlothian, Scotland.,University of Edinburgh
(author)
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Salomaa, VeikkoNatl Inst Hlth & Welf, Dept Hlth, Helsinki, Finland.,Department of Social Services and Health Care, Jakobstad
(author)
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Samani, Nilesh J.Wellcome Trust Sanger Inst, Hinxton, England.;Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England.;Glenfield Hosp, NIHR Leicester Biomed Res Ctr, Leicester, Leics, England.,Glenfield Hospital
(author)
-
Sever, Peter J.Imperial Coll London, Int Ctr Circulatory Hlth, London, England.,Imperial College London
(author)
-
Skaaby, TeaRes Ctr Prevent & Hlth, Copenhagen, Denmark.,Research Centre for Prevention and Health
(author)
-
Stafford, Jeanette M.University of Edinburgh
(author)
-
Starr, John M.Wake Forest University
(author)
-
van der Harst, PimUniv Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.;Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands.,University Medical Center Groningen
(author)
-
van der Meer, PeterUniv Groningen, Univ Med Ctr Groningen, Dept Cardiol, Groningen, Netherlands.,University Medical Center Groningen
(author)
-
van Duijn, Cornelia M.Erasmus MC, Dept Epidemiol, Genet Epidemiol Unit, Rotterdam, Netherlands.,Erasmus University Medical Center
(author)
-
Vergnaud, Anne-ClaireImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.,Imperial College London
(author)
-
Gudnason, VilmundurIceland Heart Assoc, Kopavogur, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.,University of Iceland,Icelandic Heart Association
(author)
-
Wareham, Nicholas J.Univ Cambridge, Inst Metab Sci, MRC Epidemiol Unit, Sch Clin Med, Cambridge Biomed Campus, Cambridge, England.,University of Cambridge
(author)
-
Wilson, James G.Univ Mississippi, Med Ctr, Dept Physiol & Biophys, Jackson, MS 39216 USA.
(author)
-
Willer, Cristen J.Univ Michigan, Dept Internal Med, Div Cardiovasc Med, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Computat Med & Bioinformat, Ann Arbor, MI 48109 USA.;Univ Michigan, Dept Human Genet, Ann Arbor, MI 48109 USA.,University of Michigan
(author)
-
Witte, Daniel R.Aarhus Univ, Dept Publ Hlth, Aarhus, Denmark.;Danish Diabet Acad, Odense, Denmark.
(author)
-
Zeggini, EleftheriaKuopio Univ Hosp, Kuopio, Finland.,Wellcome Trust Sanger Institute
(author)
-
Saleheen, DanishMRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.;Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA.;Ctr Noncommunicable Dis, Karachi, Pakistan.,University of Pennsylvania,University of Cambridge,Centre for Non-Communicable Diseases
(author)
-
Butterworth, Adam S.MRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.;Univ Cambridge, Cambridge Ctr Excellence, British Heart Fdn, Dept Med, Cambridge, England.,University of Cambridge
(author)
-
Danesh, JohnMRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.;NIHR Blood & Transplant Res Unit Donor Hlth & Gen, Cambridge, England.;Univ Cambridge, Cambridge Ctr Excellence, British Heart Fdn, Dept Med, Cambridge, England.;Kuopio Univ Hosp, Kuopio, Finland.,University of Cambridge,Wellcome Trust Sanger Institute
(author)
-
Asselbergs, Folkert W.UCL, Fac Populat Hlth Sci, London, England.;Univ Med Ctr Utrecht, Dept Cardiol, Utrecht, Netherlands.,University Medical Center Utrecht,University College London
(author)
-
Wain, Louise V.Univ Leicester, Dept Hlth Sci, Leicester, Leics, England.,University of Leicester
(author)
-
Ehret, Georg B.Johns Hopkins Univ, Sch Med, McKusick Nathans Inst Genet Med, Ctr Complex Dis Genom, Baltimore, MD USA.;Geneva Univ Hosp, Dept Med, Geneva, Switzerland.,Johns Hopkins University School of Medicine,Geneva University Hospital
(author)
-
Chasman, Daniel I.Hebrew SeniorLife, Dept Med, Boston, MA USA.;Harvard Med Sch, Boston, MA USA.;Brigham & Womens Hosp, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.,Brigham and Women's Hospital / Harvard Medical School,Boston University
(author)
-
Caulfield, Mark J.William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.;Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.,Queen Mary University
(author)
-
Elliott, PaulImperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.;Imperial Coll London, MRC PHE Ctr Environm & Hlth, London, England.;Imperial Coll London, Natl Inst Hlth Res Imperial Coll Healthcare NHS T, Biomed Res Unit, London, England.,Imperial College London
(author)
-
Lindgren, Cecilia M.Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England.;Univ Oxford, Big Data Inst, Li Ka Shing Ctr Hlth Informat & Discovery, Oxford, England.;Broad Inst Harvard & MIT, Program Med & Populat Genet, Cambridge, MA USA.,Broad Institute,Wellcome Trust Centre for Human Genetics,University of Oxford
(author)
-
Levy, DanielFramingham Heart Dis Epidemiol Study, Framingham, MA USA.;NHLBI, Populat Sci Branch, Div Intramural Res, Bldg 10, Bethesda, MD 20892 USA.,National Heart Lung and Blood Institute
(author)
-
Newton-Cheh, ChristopherMassachusetts Gen Hosp, Ctr Genom Med, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA.;Broad Inst Harvard & MIT, Program Med & Populat Genet, Cambridge, MA USA.,Massachusetts General Hospital,Broad Institute
(author)
-
Munroe, Patricia B.William Harvey Res Inst, Dept Clin Pharmacol, London, England.;Queen Mary Univ London, London Sch Med & Dent, London, England.,Queen Mary University
(author)
-
Howson, Joanna M. M.Queen Mary Univ London, Natl Inst Hlth Res, Baits Cardiovasc Biomed Res Unit, London, England.;MRC BHF Cardiovasc Epidemiol Ctr, Dept Publ Hlth & Primary Care, Cambridge, England.,University of Cambridge
(author)
-
Käräjämäki, Anne MariVaasa Central Hospital
(author)
-
Umeå universitetEnheten för biobanksforskning
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