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Hematopoietic Stem Cell Transplantation Activity in Pediatric Cancer between 2008 and 2014 in the United States : A Center for International Blood and Marrow Transplant Research Report
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- Khandelwal, Pooja (författare)
- Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplantat & Immune Deficiency, Cincinnati, OH 45229 USA
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- Millard, Heather R. (författare)
- Med Coll Wisconsin, Ctr Int Blood & Marrow Transplant Res, Dept Med, Milwaukee, WI 53226 USA
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- Thiel, Elizabeth (författare)
- Med Coll Wisconsin, Ctr Int Blood & Marrow Transplant Res, Dept Med, Milwaukee, WI 53226 USA
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- Abdel-Azim, Hisham (författare)
- Univ Southern Calif, Keck Sch Med, Childrens Hosp Los Angeles, Div Hematol Oncol & Blood & Marrow Transplantat, Los Angeles, CA 90033 USA
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- Abraham, Allistair A. (författare)
- Childrens Natl Med Ctr, Div Blood & Marrow Transplantat, Ctr Canc & Blood Disorders, Washington, DC 20010 USA
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- Auletta, Jeffery J. (författare)
- Nationwide Childrens Hosp, Host Def Program, Div Hematol Oncol Bone Marrow Transplant & Infect, Columbus, OH USA
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- Boulad, Farid (författare)
- Mem Sloan Kettering Canc Ctr, Dept Pediat, New York, NY 10021 USA
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- Brown, Valerie I. (författare)
- Penn State Hershey Childrens Hosp, Coll Med, Div Pediat Hematol Oncol, Dept Pediat, Hershey, PA USA
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- Camitta, Bruce M. (författare)
- Childrens Hosp Wisconsin, Milwaukee, WI 53201 USA;Med Coll Wisconsin, Midwest Ctr Canc & Blood Disorders, Milwaukee, WI 53226 USA
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- Chan, Ka Wah (författare)
- Texas Transplant Inst, Dept Pediat, San Antonio, TX USA
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- Chaudhury, Sonali (författare)
- Ann & Robert H Lurie Childrens Hosp Chicago, Div Pediat Hematol Oncol & Stem Cell Transplant, Dept Pediat, Chicago, IL 60611 USA
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- Cowan, Morton J. (författare)
- UCSF Benioff Childrens Hosp, Pediat Allergy Immunol & Blood & Marrow Transplan, San Francisco, CA USA
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- Angel-Diaz, Miguel (författare)
- Univ Nino Jesus, Hosp Infantil, Dept Hematol Oncol, Madrid, Spain
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- Gadalla, Shahinaz M. (författare)
- NCI, Div Canc Epidemiol & Genet, Clin Genet Branch, NIH, Rockville, MD USA
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- Gale, Robert Peter (författare)
- Imperial Coll London, Hematol Res Ctr, Div Expt Med, Dept Med, London, England
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- Hale, Gregory (författare)
- Johns Hopkins All Childrens Hosp, Dept Hematol Oncol, St Petersburg, FL USA
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- Kasow, Kimberly A. (författare)
- Univ North Carolina Chapel Hill, Div Hematol Oncol, Dept Pediat, Chapel Hill, NC USA
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- Keating, Amy K. (författare)
- Univ Colorado, Sch Med, Dept Pediat, Aurora, CO USA
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- Kitko, Carrie L. (författare)
- Vanderbilt Univ, Med Ctr, Pediat Hematol Oncol Div, Nashville, TN 37235 USA
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- MacMillan, Margaret L. (författare)
- Univ Minnesota, Blood & Marrow Transplant Program, Minneapolis, MN USA
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- Olsson, Richard (författare)
- Karolinska Institutet,Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Div Therapeut Immunol, Dept Lab Med, Stockholm, Sweden
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- Page, Kristin M. (författare)
- Duke Univ, Med Ctr, Div Pediat Blood & Marrow Transplantat, Durham, NC USA
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- Seber, Adriana (författare)
- Univ Sao Paulo, Sch Med, Internal Med, Sao Paulo, Brazil
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- Smith, Angela R. (författare)
- Univ Minnesota, Blood & Marrow Transplant Program, Minneapolis, MN USA
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- Warwick, Anne B. (författare)
- Uniformed Serv Univ Hlth Sci, Dept Pediat, Bethesda, MD 20814 USA
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- Wirk, Baldeep (författare)
- Seattle Canc Care Alliance, Div Bone Marrow Transplant, Seattle, WA USA
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- Mehta, Parinda A. (författare)
- Cincinnati Childrens Hosp Med Ctr, Div Bone Marrow Transplantat & Immune Deficiency, Cincinnati, OH 45229 USA
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(creator_code:org_t)
- Elsevier BV, 2017
- 2017
- Engelska.
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Ingår i: Biology of blood and marrow transplantation. - : Elsevier BV. - 1083-8791 .- 1523-6536. ; 23:8, s. 1342-1349
- Relaterad länk:
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http://www.bbmt.org/...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- This Center for International Blood and Marrow Transplant Research report describes the use of hematopoietic stem cell transplantation (HSCT) in pediatric patients with cancer, 4408 undergoing allogeneic (allo) and3076 undergoing autologous (auto) HSCT in the United States between 2008 and 2014. In both settings, there was a greater proportion of boys (n = 4327; 57%), children < 10 years of age (n = 4412; 59%), whites (n = 5787; 77%), and children with a performance score 90% at HSCT (n = 6187; 83%). Leukemia was the most common indication for an allo-transplant (n = 4170; 94%), and among these, acute lymphoblastic leukemia in second complete remission (n = 829; 20%) and acute myeloid leukemia in first complete remission (n = 800; 19%) were the most common. The most frequently used donor relation, stem cell sources, and HLA match were unrelated donor (n = 2933; 67%), bone marrow (n = 2378; 54%), and matched at 8/8 HLA antigens (n = 1098; 37%) respectively. Most allo-transplants used myeloablative conditioning (n = 4070; 92%) and calcineurin inhibitors and methotrexate (n = 2245; 51%) for acute graft-versus-host disease prophylaxis. Neuroblastoma was the most common primary neoplasm for an auto-transplant (n = 1338; 44%). Tandem auto-transplants for neuroblastoma declined after 2012 (40% in 2011, 25% in 2012, and 8% in 2014), whereas tandem auto transplants increased for brain tumors (57% in 2008 and 77% in 2014). Allo-transplants from relatives other than HLA-identical siblings doubled between 2008 and 2014 (3% in 2008 and 6% in 2014). These trends will be monitored in future reports of transplant practices in the United States.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- Hematopoietic stem cell transplantation
- Pediatric cancers
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- Av författaren/redakt...
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Khandelwal, Pooj ...
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Millard, Heather ...
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Thiel, Elizabeth
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Abdel-Azim, Hish ...
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Abraham, Allista ...
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Auletta, Jeffery ...
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visa fler...
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Boulad, Farid
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Brown, Valerie I ...
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Camitta, Bruce M ...
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Chan, Ka Wah
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Chaudhury, Sonal ...
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Cowan, Morton J.
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Angel-Diaz, Migu ...
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Gadalla, Shahina ...
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Gale, Robert Pet ...
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Hale, Gregory
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Kasow, Kimberly ...
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Keating, Amy K.
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Kitko, Carrie L.
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MacMillan, Marga ...
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Olsson, Richard
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Page, Kristin M.
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Seber, Adriana
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Smith, Angela R.
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Warwick, Anne B.
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Wirk, Baldeep
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Mehta, Parinda A ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Hematologi
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Biology of blood ...
- Av lärosätet
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Uppsala universitet
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Karolinska Institutet