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Detection and quant...
Detection and quantification of beta cells by PET imaging : why clinical implementation has never been closer
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- Gotthardt, Martin (author)
- Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, POB 9101, NL-6500 HB Nijmegen, Netherlands
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- Eizirik, Decio L. (author)
- Univ Libre Bruxelles, Fac Med, ULB Ctr Diabet Res, Brussels, Belgium
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- Aanstoot, Henk-Jan (author)
- Ctr Pediat & Adolescent Diabet Care & Res, Diabeter, Rotterdam, Netherlands
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- Korsgren, Olle (author)
- Uppsala universitet,Klinisk immunologi
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- Mul, Dick (author)
- Ctr Pediat & Adolescent Diabet Care & Res, Diabeter, Rotterdam, Netherlands
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- Martin, Frank (author)
- JDRF, New York, NY USA
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- Boss, Marti (author)
- Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, POB 9101, NL-6500 HB Nijmegen, Netherlands
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- Jansen, Tom J. P. (author)
- Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, POB 9101, NL-6500 HB Nijmegen, Netherlands
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- van Lith, Sanne A. M. (author)
- Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, POB 9101, NL-6500 HB Nijmegen, Netherlands
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- Buitinga, Mijke (author)
- Univ Leuven, Clin & Expt Endocrinol, Leuven, Belgium
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- Eriksson, Olof (author)
- Uppsala universitet,Theranostics
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- Cnop, Miriam (author)
- Univ Libre Bruxelles, Fac Med, ULB Ctr Diabet Res, Brussels, Belgium;Univ Libre Bruxelles, Erasmus Hosp, Div Endocrinol, Brussels, Belgium
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- Brom, Maarten (author)
- Radboud Univ Nijmegen, Med Ctr, Dept Radiol & Nucl Med, POB 9101, NL-6500 HB Nijmegen, Netherlands
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(creator_code:org_t)
- 2018-10-03
- 2018
- English.
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In: Diabetologia. - : SPRINGER. - 0012-186X .- 1432-0428. ; 61:12, s. 2516-2519
- Related links:
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https://link.springe...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- In this issue of Diabetologia, Alavi and Werner (10.1007/s00125-018-4676-1) criticise the attempts to use positron emission tomography (PET) for in vivo imaging of pancreatic beta cells, which they consider as futile'. In support of this strong statement, they point out the limitations of PET imaging, which they believe render beta cell mass impossible to estimate using this method. In our view, the Alavi and Werner presentation of the technical limitations of PET imaging does not reflect the current state of the art, which leads them to questionable conclusions towards the feasibility of beta cell imaging using this approach. Here, we put forward arguments in favour of continuing the development of innovative technologies enabling in vivo imaging of pancreatic beta cells and concisely present the current state of the art regarding putative technical limitations of PET imaging. Indeed, far from being a futile' effort, we demonstrate that beta cell imaging is now closer than ever to becoming a long-awaited clinical reality.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Keyword
- Clinical diabetes
- Imaging
- Islets
- PET imaging
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Gotthardt, Marti ...
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Eizirik, Decio L ...
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Aanstoot, Henk-J ...
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Korsgren, Olle
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Mul, Dick
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Martin, Frank
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Boss, Marti
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Jansen, Tom J. P ...
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van Lith, Sanne ...
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Buitinga, Mijke
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Eriksson, Olof
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Cnop, Miriam
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Brom, Maarten
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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Diabetologia
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Uppsala University