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Development of Mous...
Development of Mouse Monoclonal Antibodies Against Human Amyloid Fibril Proteins for Diagnostic and Research Purposes
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Westermark, Gunilla T (författare)
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- Ihse, Elisabet, 1977- (författare)
- Uppsala universitet,Klinisk och experimentell patologi,Per Westermark
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- Westermark, Per (författare)
- Uppsala universitet,Klinisk och experimentell patologi,Per Westermark
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(creator_code:org_t)
- 2018-06-08
- 2018
- Engelska.
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Ingår i: Methods in Molecular Biology. - New York, NY : Springer New York. - 1064-3745 .- 1940-6029. ; 1779, s. 401-414
- Relaterad länk:
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https://urn.kb.se/re...
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visa fler...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Commercial antibodies against varying proteins are often not optimal for identification of proteins in their amyloid fibril forms. Reasons can be the different conformation but also a variety of modifications like N- or C-terminal truncation. Therefore, development of own monoclonal antibodies against amyloid fibril proteins may be advantageous. This chapter gives suggestions of how to be successful in such approaches.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Nyckelord
- Amyloid
- Degraded amyloid
- Fibril
- Hybridoma
- Immunohistochemistry
- Transthyretin
- Western blot
- Patologi
- Pathology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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