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- Kaluza, JoannaKarolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden;Warsaw Univ Life Sci, Fac Human Nutr & Consumer Sci, Dept Human Nutr, 159C Nowoursynowska St, PL-02776 Warsaw, Poland (författare)
Alcohol Consumption and Risk of Chronic Obstructive Pulmonary Disease : A Prospective Cohort Study of Men
- Artikel/kapitelEngelska2019
Förlag, utgivningsår, omfång ...
- 2019-03-16
- OXFORD UNIV PRESS INC,2019
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:uu-397298
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-397298URI
- https://doi.org/10.1093/aje/kwz020DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:142199022URI
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- Språk:engelska
- Sammanfattning på:engelska
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- Studies indicate an inverse association between moderate alcohol consumption and chronic inflammatory diseases; however, the association between alcohol consumption and chronic obstructive pulmonary disease (COPD) incidence has not been widely studied. We investigated the associations of total alcohol consumption and intake of specific alcoholic beverages with risk of COPD in a population-based prospective cohort study, the Cohort of Swedish Men (n = 44,254). Alcohol consumption was assessed with a self-administered questionnaire in 1997. During follow-up (1998-2014), 2,177 COPD cases were ascertained. Moderate alcohol consumption was associated with the lowest risk of COPD. A J-shaped association was observed for ethanol consumption (P for nonlinearity = 0.003) and beer consumption (P for nonlinearity < 0.001); for wine consumption, a U-shaped association was observed (P for nonlinearity < 0.001). Defining a "standard drink" as 12 g of ethanol, the multivariable-adjusted hazard ratios were 0.77 (95% confidence interval (CI): 0.66, 0.90) and 0.92 (95% CI: 0.81, 1.05) for beer consumption of 4.1-6.0 and >6.0 standard drinks/week (SDW) versus <1.0 SDW, respectively; 0.80 (95% CI: 0.69, 0.93) and 1.00 (95% CI: 0.83, 1.21) for wine consumption of 2.0-4.0 and >4.0 SDW versus <1.0 SDW, respectively; and 1.10 (95% CI: 0.98, 1.24) and 1.20 (95% CI: 0.99, 1.44) for liquor consumption of 2.0-4.0 and >4.0 SDW versus <1.0 SDW, respectively. In conclusion, our findings suggest that moderate beer and wine consumption, but not liquor consumption, may decrease risk of COPD. Additional studies are needed to confirm these associations.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
- alcohol consumption
- chronic obstructive pulmonary disease
- ethanol
- prospective cohort studies
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Harris, Holly R.Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, Seattle, WA 98104 USA (författare)
- Linden, AndersKarolinska Institutet (författare)
- Wolk, AlicjaKarolinska Institutet,Uppsala universitet,Institutionen för kirurgiska vetenskaper,Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden;(Swepub:uu)alwol516 (författare)
- Karolinska Inst, Inst Environm Med, Unit Cardiovasc & Nutr Epidemiol, Stockholm, Sweden;Warsaw Univ Life Sci, Fac Human Nutr & Consumer Sci, Dept Human Nutr, 159C Nowoursynowska St, PL-02776 Warsaw, PolandFred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Program Epidemiol, Seattle, WA 98104 USA (creator_code:org_t)
Sammanhörande titlar
- Ingår i:American Journal of Epidemiology: OXFORD UNIV PRESS INC188:5, s. 907-9160002-92621476-6256
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- Kaluza, Joanna
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