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Combined impact of ...
Combined impact of healthy lifestyle factors on risk of atrial fibrillation : Prospective study in men and women.
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- Larsson, Susanna C. (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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- Drca, Nikola (författare)
- Karolinska Institutet
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- Jensen-Urstad, Mats (författare)
- Karolinska Institutet
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- Wolk, Alicja (författare)
- Karolinska Institutet,Uppsala universitet,Ortopedi
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(creator_code:org_t)
- Elsevier, 2016
- 2016
- Engelska.
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Ingår i: International Journal of Cardiology. - : Elsevier. - 0167-5273 .- 1874-1754. ; 203, s. 46-9
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The combined impact of multiple lifestyle factors on risk of atrial fibrillation (AF) remains unclear. We investigated the joint association of four modifiable lifestyle factors on incidence of AF in a prospective study of men and women.METHODS: The study cohort comprised 39 300 men in the Cohort of Swedish Men and 33 090 women in the Swedish Mammography Cohort who were 45-83 years of age and free from atrial fibrillation at baseline. Healthy lifestyle was defined as body mass index <25 kg/m(2), regular exercise for ≥ 20 min/day, no or light-to-moderate alcohol consumption (≤ 2 drinks/day for men and ≤ 1 drink/day for women), and not smoking. Incident AF cases were identified through linkage with the Swedish National Inpatient Register.RESULTS: During a mean follow-up of 10.9 years, AF occurred in 4028 men and 2539 women. Compared with men and women with no healthy lifestyle factors, the multivariable relative risks (95% confidence interval) of AF were 0.83 (0.65-1.07) for one, 0.74 (0.58-0.94) for two, 0.62 (0.49-0.79) for three, and 0.50 (0.39-0.64) for four healthy lifestyle factors (P for trend <0.0001). The inverse association was similar in men and women.CONCLUSIONS: Four healthy lifestyle factors combined were associated with a halving of the risk of AF.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Alcohol
- Atrial fibrillation
- Body mass index
- Lifestyle
- Physical activity
- Smoking
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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