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Sökning: WFRF:(Asayama K) > (2019) > Opposing Age-Relate...

Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure

Li, Yan (författare)
Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
Thijs, Lutgarde (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
Zhang, Zhen-Yu (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
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Asayama, Kei (författare)
Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
Hansen, Tine W. (författare)
Steno Diabet Ctr Copenhagen, Gentofte, Denmark
Boggia, Jose (författare)
Univ Republica, Ctr Nefrol, Montevideo, Uruguay;Univ Republica, Dept Fisiopatol, Hosp Clin, Montevideo, Uruguay
Bjoerklund-Bodegard, Kristina (författare)
Karolinska Inst, Div Cardiovasc Med, Dept Clin Sci, Danderyd Hosp, Stockholm, Sweden
Yang, Wen-Yi (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
Niiranen, Teemu J. (författare)
Natl Inst Hlth & Welf, Turku, Finland;Turku Univ Hosp, Dept Med, Turku, Finland;Univ Turku, Turku, Finland
Ntineri, Angeliki (författare)
Univ Athens, Hypertens Ctr STRIDE 7, Sch Med, Sotiria Hosp,Dept Med 3, Athens, Greece
Wei, Fang-Fei (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
Kikuya, Masahiro (författare)
Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan
Ohkubo, Takayoshi (författare)
Teikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
Dolan, Eamon (författare)
Stroke & Hypertens Unit, Dublin, Ireland
Hozawa, Atsushi (författare)
Tohoku Univ, Tohoku Med Megabank Org, Dept Prevent Med & Epidemiol, Sendai, Miyagi, Japan
Tsuji, Ichiro (författare)
Tohoku Univ, Dept Publ Hlth, Grad Sch Med, Sendai, Miyagi, Japan
Stolarz-Skrzypek, Katarzyna (författare)
Jagiellonian Univ, Dept Cardiol 1, Intervent Electrocardiol & Hypertens, Coll Med, Krakow, Poland
Huang, Qi-Fang (författare)
Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
Melgarejo, Jesus D. (författare)
Univ Zulia, Lab Neurociencias, Maracaibo, Venezuela;Univ Zulia, Inst Cardiovasc, Maracaibo, Venezuela
Tikhonoff, Valerie (författare)
Univ Padua, Dept Med, Padua, Italy
Malyutina, Sofia (författare)
Russian Acad Sci, Inst Internal & Prevent Med Internal & Prevent Me, Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia
Casiglia, Edoardo (författare)
Univ Padua, Dept Med, Padua, Italy
Nikitin, Yuri (författare)
Russian Acad Sci, Inst Internal & Prevent Med Internal & Prevent Me, Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia
Lind, Lars (författare)
Uppsala universitet,Geriatrik
Sandoya, Edgardo (författare)
Asociac Espanola Primera Socorros Mutuos, Montevideo, Uruguay
Aparicio, Lucas (författare)
Univ Buenos Aires, Hosp Italiano Buenos Aires, Dept Med, Buenos Aires, DF, Argentina
Barochiner, Jessica (författare)
Univ Buenos Aires, Hosp Italiano Buenos Aires, Dept Med, Buenos Aires, DF, Argentina
Gilis-Malinowska, Natasza (författare)
Med Univ Gdansk, Dept Hypertens, Gdansk, Poland
Narkiewicz, Krzysztof (författare)
Med Univ Gdansk, Dept Hypertens, Gdansk, Poland
Kawecka-Jaszcz, Kalina (författare)
Jagiellonian Univ, Dept Cardiol 1, Intervent Electrocardiol & Hypertens, Coll Med, Krakow, Poland
Maestre, Gladys E. (författare)
Univ Zulia, Lab Neurociencias, Maracaibo, Venezuela;Univ Zulia, Inst Cardiovasc, Maracaibo, Venezuela;Univ Texas Rio Grande Valley, Dept Neurosci, Brownsville, TX USA;Univ Texas Rio Grande Valley, Dept Human Genet, Brownsville, TX USA
Jula, Antti M. (författare)
Natl Inst Hlth & Welf, Turku, Finland
Johansson, Jouni K. (författare)
Natl Inst Hlth & Welf, Turku, Finland
Kuznetsova, Tatiana (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
Filipovsky, Jan (författare)
Charles Univ Prague, Fac Med, Plzen, Czech Republic
Stergiou, George (författare)
Univ Athens, Hypertens Ctr STRIDE 7, Sch Med, Sotiria Hosp,Dept Med 3, Athens, Greece
Wang, Ji-Guang (författare)
Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
Imai, Yutaka (författare)
Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
O'Brien, Eoin (författare)
Univ Coll Dublin, Conway Inst, Dublin, Ireland
Staessen, Jan A. (författare)
Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium;Maastricht Univ, Cardiovasc Res Inst Maastricht CARIM, Maastricht, Netherlands
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 (creator_code:org_t)
Lippincott Williams & Wilkins, 2019
2019
Engelska.
Ingår i: Hypertension. - : Lippincott Williams & Wilkins. - 0194-911X .- 1524-4563. ; 74:6, s. 1333-1342
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
http://kipublication...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Participant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office blood pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) blood pressure were measured in 17 921 participants (51.3% women; mean age, 54.2 years) from 17 population cohorts. Subsequently, mortality and cardiovascular events were recorded. Using multivariable Cox regression, floating absolute risk was computed across 4 age bands (<= 60, 61-70, 71-80, and >80 years). Over 236 491 person-years, 3855 people died and 2942 cardiovascular events occurred. From levels as low as 110/65 mm Hg, risk log-linearly increased with higher out-of-office systolic/diastolic blood pressure. From the youngest to the oldest age group, rates expressed per 1000 person-years increased (P<0.001) from 4.4 (95% CI, 4.0-4.7) to 86.3 (76.1-96.5) for all-cause mortality and from 4.1 (3.9-4.6) to 59.8 (51.0-68.7) for cardiovascular events, whereas hazard ratios per 20-mm Hg increment in systolic out-of-office blood pressure decreased (P <= 0.0033) from 1.42 (1.19-1.69) to 1.09 (1.05-1.12) and from 1.70 (1.51-1.92) to 1.12 (1.07-1.17), respectively. These age-related trends were similar for out-of-office diastolic pressure and were generally consistent in both sexes and across ethnicities. In conclusion, adverse outcomes were directly associated with out-of-office blood pressure in adults. At young age, the absolute risk associated with out-of-office blood pressure was low, but relative risk high, whereas with advancing age relative risk decreased and absolute risk increased. These observations highlight the need of a lifecourse approach for the management of hypertension.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

blood pressure
blood pressure monitoring
ambulatory
cardiovascular diseases
hypertension
mortality

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