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Opposing Age-Relate...
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Li, YanShanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
(author)
Opposing Age-Related Trends in Absolute and Relative Risk of Adverse Health Outcomes Associated With Out-of-Office Blood Pressure
- Article/chapterEnglish2019
Publisher, publication year, extent ...
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Lippincott Williams & Wilkins,2019
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-398690
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-398690URI
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https://doi.org/10.1161/HYPERTENSIONAHA.119.12958DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:142375297URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Participant-level meta-analyses assessed the age-specific relevance of office blood pressure to cardiovascular complications, but this information is lacking for out-of-office blood pressure. At baseline, daytime ambulatory (n=12 624) or home (n=5297) blood pressure were measured in 17 921 participants (51.3% women; mean age, 54.2 years) from 17 population cohorts. Subsequently, mortality and cardiovascular events were recorded. Using multivariable Cox regression, floating absolute risk was computed across 4 age bands (<= 60, 61-70, 71-80, and >80 years). Over 236 491 person-years, 3855 people died and 2942 cardiovascular events occurred. From levels as low as 110/65 mm Hg, risk log-linearly increased with higher out-of-office systolic/diastolic blood pressure. From the youngest to the oldest age group, rates expressed per 1000 person-years increased (P<0.001) from 4.4 (95% CI, 4.0-4.7) to 86.3 (76.1-96.5) for all-cause mortality and from 4.1 (3.9-4.6) to 59.8 (51.0-68.7) for cardiovascular events, whereas hazard ratios per 20-mm Hg increment in systolic out-of-office blood pressure decreased (P <= 0.0033) from 1.42 (1.19-1.69) to 1.09 (1.05-1.12) and from 1.70 (1.51-1.92) to 1.12 (1.07-1.17), respectively. These age-related trends were similar for out-of-office diastolic pressure and were generally consistent in both sexes and across ethnicities. In conclusion, adverse outcomes were directly associated with out-of-office blood pressure in adults. At young age, the absolute risk associated with out-of-office blood pressure was low, but relative risk high, whereas with advancing age relative risk decreased and absolute risk increased. These observations highlight the need of a lifecourse approach for the management of hypertension.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Thijs, LutgardeUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
(author)
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Zhang, Zhen-YuUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
(author)
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Asayama, KeiTeikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
(author)
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Hansen, Tine W.Steno Diabet Ctr Copenhagen, Gentofte, Denmark
(author)
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Boggia, JoseUniv Republica, Ctr Nefrol, Montevideo, Uruguay;Univ Republica, Dept Fisiopatol, Hosp Clin, Montevideo, Uruguay
(author)
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Bjoerklund-Bodegard, KristinaKarolinska Inst, Div Cardiovasc Med, Dept Clin Sci, Danderyd Hosp, Stockholm, Sweden
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Yang, Wen-YiUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
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Niiranen, Teemu J.Natl Inst Hlth & Welf, Turku, Finland;Turku Univ Hosp, Dept Med, Turku, Finland;Univ Turku, Turku, Finland
(author)
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Ntineri, AngelikiUniv Athens, Hypertens Ctr STRIDE 7, Sch Med, Sotiria Hosp,Dept Med 3, Athens, Greece
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Wei, Fang-FeiUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
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Kikuya, MasahiroTeikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan
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Ohkubo, TakayoshiTeikyo Univ, Sch Med, Dept Hyg & Publ Hlth, Tokyo, Japan;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
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Dolan, EamonStroke & Hypertens Unit, Dublin, Ireland
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Hozawa, AtsushiTohoku Univ, Tohoku Med Megabank Org, Dept Prevent Med & Epidemiol, Sendai, Miyagi, Japan
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Tsuji, IchiroTohoku Univ, Dept Publ Hlth, Grad Sch Med, Sendai, Miyagi, Japan
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Stolarz-Skrzypek, KatarzynaJagiellonian Univ, Dept Cardiol 1, Intervent Electrocardiol & Hypertens, Coll Med, Krakow, Poland
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Huang, Qi-FangShanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
(author)
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Melgarejo, Jesus D.Univ Zulia, Lab Neurociencias, Maracaibo, Venezuela;Univ Zulia, Inst Cardiovasc, Maracaibo, Venezuela
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Tikhonoff, ValerieUniv Padua, Dept Med, Padua, Italy
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Malyutina, SofiaRussian Acad Sci, Inst Internal & Prevent Med Internal & Prevent Me, Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia
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Casiglia, EdoardoUniv Padua, Dept Med, Padua, Italy
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Nikitin, YuriRussian Acad Sci, Inst Internal & Prevent Med Internal & Prevent Me, Inst Cytol & Genet, Siberian Branch, Novosibirsk, Russia
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Lind, LarsUppsala universitet,Geriatrik(Swepub:uu)larslind
(author)
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Sandoya, EdgardoAsociac Espanola Primera Socorros Mutuos, Montevideo, Uruguay
(author)
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Aparicio, LucasUniv Buenos Aires, Hosp Italiano Buenos Aires, Dept Med, Buenos Aires, DF, Argentina
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Barochiner, JessicaUniv Buenos Aires, Hosp Italiano Buenos Aires, Dept Med, Buenos Aires, DF, Argentina
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Gilis-Malinowska, NataszaMed Univ Gdansk, Dept Hypertens, Gdansk, Poland
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Narkiewicz, KrzysztofMed Univ Gdansk, Dept Hypertens, Gdansk, Poland
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Kawecka-Jaszcz, KalinaJagiellonian Univ, Dept Cardiol 1, Intervent Electrocardiol & Hypertens, Coll Med, Krakow, Poland
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Maestre, Gladys E.Univ Zulia, Lab Neurociencias, Maracaibo, Venezuela;Univ Zulia, Inst Cardiovasc, Maracaibo, Venezuela;Univ Texas Rio Grande Valley, Dept Neurosci, Brownsville, TX USA;Univ Texas Rio Grande Valley, Dept Human Genet, Brownsville, TX USA
(author)
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Jula, Antti M.Natl Inst Hlth & Welf, Turku, Finland
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Johansson, Jouni K.Natl Inst Hlth & Welf, Turku, Finland
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Kuznetsova, TatianaUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
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Filipovsky, JanCharles Univ Prague, Fac Med, Plzen, Czech Republic
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Stergiou, GeorgeUniv Athens, Hypertens Ctr STRIDE 7, Sch Med, Sotiria Hosp,Dept Med 3, Athens, Greece
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Wang, Ji-GuangShanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R China
(author)
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Imai, YutakaTohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan
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O'Brien, EoinUniv Coll Dublin, Conway Inst, Dublin, Ireland
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Staessen, Jan A.Univ Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium;Maastricht Univ, Cardiovasc Res Inst Maastricht CARIM, Maastricht, Netherlands
(author)
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Shanghai Jiao Tong Univ, Sch Med, Ctr Epidemiol Studies, Shanghai, Peoples R China;Shanghai Jiao Tong Univ, Clin Trials & Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp, Shanghai, Peoples R ChinaUniv Leuven, Dept Cardiovasc Sci, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Leuven, Belgium
(creator_code:org_t)
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In:Hypertension: Lippincott Williams & Wilkins74:6, s. 1333-13420194-911X1524-4563
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Li, Yan
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Thijs, Lutgarde
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Zhang, Zhen-Yu
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Asayama, Kei
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Hansen, Tine W.
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Boggia, Jose
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Yang, Wen-Yi
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Wei, Fang-Fei
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Kikuya, Masahiro
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Ohkubo, Takayosh ...
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Dolan, Eamon
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Hozawa, Atsushi
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Tsuji, Ichiro
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Stolarz-Skrzypek ...
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Huang, Qi-Fang
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Melgarejo, Jesus ...
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Tikhonoff, Valer ...
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Malyutina, Sofia
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Sandoya, Edgardo
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Aparicio, Lucas
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Hypertension
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