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FeNO level and alle...
FeNO level and allergy status among school children in Terengganu, Malaysia
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- Ma'pol, Aminnuddin (author)
- Gombak District Health Office, Ministry of Health, Batu Caves, Selangor Darul Ehsan, Malaysia
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- Hashim, Jamal Hisham (author)
- United Nations University, International Institute for Global Health (UNU-IIGH), Kuala Lumpur, Malaysia
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- Norbäck, Dan (author)
- Uppsala universitet,Arbets- och miljömedicin
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- Wieslander, Gunilla (author)
- Uppsala universitet,Arbets- och miljömedicin
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- Hashim, Zailina (author)
- Department of Environmental and OccupationalHealth, Faculty of Medicine and Health Sciences, Universiti Putra Selangor, Selangor, Malaysia
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- Isa, Zaleha Md (author)
- Department of Community Health,UKM Medical Centre, National University of Malaysia, Kuala Lumpur, Cheras, Malaysia
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(creator_code:org_t)
- 2019-06-03
- 2020
- English.
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In: Journal of Asthma. - : Informa UK Limited. - 0277-0903 .- 1532-4303. ; 57:8, s. 842-849
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background: Almost one third of the world population suffers from allergic conditions. Respiratory symptoms are common in Malaysian children but there are few studies on fractional exhaled nitric oxide (FeNO), inclusive of field clinical test for asthma among children in Malaysia. The aim was to provide insight on factors related to level of FeNO among students in Terengganu, Malaysia. Methods: In total, 487 randomly selected students from eight secondary schools participated (13-14 years old). A Standardized questionnaire was used to obtained information on doctors' diagnosed asthma, current asthma and respiratory symptoms. FeNO measurement and skin prick test (SPT to common allergen) were conducted. Results: The geometric mean FeNO was 16.7 ppb. Totally, 38.4% of students had elevated FeNO level (>20 ppb) and 40.3% had had positive SPT to house dust mites allergens (HDM), Dermatophagoides pteronyssinus (Der p 1), Dermatophagoides farinae (Der f 1) or Felis domisticus (cat). Male gender, height, parental history of allergy, self-reported allergy, and atopy were associated with FeNO. In particular, a combination of sensitization to HDM or cat and elevated FeNO were associated with doctor-diagnosed asthma and self-reported allergy to food, pollen and cat. Conclusion: Asthma, respiratory symptoms and sensitization to HDM and cat are common among students and presence of elevated FeNO levels indicate ongoing airway inflammation.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Keyword
- FeNO
- Malaysia
- Students
- allergy
- asthma
Publication and Content Type
- ref (subject category)
- art (subject category)
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