Search: WFRF:(Martinez Moratalla Jesús)
> (2015-2019) >
The role of C-react...
The role of C-reactive protein levels on the association of physical activity with lung function in adults
-
Fuertes, Elaine (author)
-
Carsin, Anne-Elie (author)
-
Garcia-Larsen, Vanessa (author)
-
show more...
-
Guerra, Stefano (author)
-
Pin, Isabelle (author)
-
Leynaert, Bénédicte (author)
-
Accordini, Simone (author)
-
Martinez-Moratalla, Jesús (author)
-
Antó, Josep M. (author)
-
Urrutia, Isabel (author)
-
Le Gouellec, Audrey (author)
-
Heinrich, Joachim (author)
-
Gislason, Thorarinn (author)
-
- Jögi, Rain (author)
- Lung Clinic, Tartu University Hospital, Tartu, Estonia
-
- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
-
Jarvis, Debbie (author)
-
Garcia-Aymerich, Judith (author)
-
show less...
-
(creator_code:org_t)
- 2019-09-23
- 2019
- English.
-
In: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:9
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://uu.diva-port... (primary) (Raw object)
-
https://journals.plo...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- OBJECTIVE: Regular physical activity may be associated with improved lung function via reduced systemic inflammation, although studies exploring this mechanism are rare. We evaluated the role of C-reactive protein in blood, which is a common marker of systemic inflammation, on the association of physical activity with forced expiratory volume in one second and forced vital capacity.METHODS: Cross-sectional data on spirometry, C-reactive protein levels and self-reported physical activity (yes/no; ≥2 times and ≥1hr per week of vigorous physical activity) were available in the European Community Respiratory Health Survey (N = 2347 adults, 49.3% male, 28-56 years-old). A subsample was also assessed 10 years later using the International Physical Activity Questionnaire, and tertiles of Metabolic Equivalent of Task-minutes per week spent in vigorous, moderate and walking activities were calculated (N = 671, 49.6% male, 40-67 years-old). Adjusted cross-sectional mixed linear regression models and the "mediate" package in "R" were used to assess the presence of mediation.RESULTS: Despite positive significant associations between nearly all physical activity metrics with forced expiratory volume in one second and forced vital capacity, there was no evidence that C-reactive protein levels played a role. An influence of C-reactive protein levels was only apparent in the smaller subsample when comparing the medium to low tertiles of moderate activity (mean difference [95% CIs]: 21.1ml [5.2, 41.9] for forced expiratory volume in one second and 17.3ml [2.6, 38.0] for forced vital capacity).CONCLUSIONS: In a population of adults, we found no consistent evidence that the association of physical activity with forced expiratory volume in one second or forced vital capacity is influenced by the level of C-reactive protein in blood.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
-
PLOS ONE
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Fuertes, Elaine
-
Carsin, Anne-Eli ...
-
Garcia-Larsen, V ...
-
Guerra, Stefano
-
Pin, Isabelle
-
Leynaert, Bénédi ...
-
show more...
-
Accordini, Simon ...
-
Martinez-Moratal ...
-
Antó, Josep M.
-
Urrutia, Isabel
-
Le Gouellec, Aud ...
-
Heinrich, Joachi ...
-
Gislason, Thorar ...
-
Jögi, Rain
-
Janson, Christer
-
Jarvis, Debbie
-
Garcia-Aymerich, ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Respiratory Medi ...
- Articles in the publication
-
PLOS ONE
- By the university
-
Uppsala University