Search: WFRF:(Mauricio Montenegro Omar)
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Effects of oxygen o...
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Ferrando, CarlosHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain
(author)
Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy : a randomised controlled trial
- Article/chapterEnglish2020
Publisher, publication year, extent ...
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ELSEVIER SCI LTD,2020
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:uu-401176
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401176URI
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https://doi.org/10.1016/j.bja.2019.10.009DOI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background: We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery. Methods: We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin saturation. The primary outcome was the prevalence of SSI within the first 7 postoperative days. The secondary outcomes were composites of systemic complications, length of intensive care and hospital stay, and 6-month mortality. Results: We enrolled 740 subjects: 371 in the high FIO2 group and 369 in the low FIO2 group. Data from 717 subjects were available for final analysis. The rate of SSI during the first postoperative week did not differ between high (8.9%) and low (9.4%) FIO2 groups (relative risk [RR]: 0.94; 95% confidence interval [CI]: 0.59-1.50; P=0.90]). Secondary outcomes, such as atelectasis (7.7% vs 9.8%; RR: 0.77; 95% CI: 0.48-1.25; P=0.38) and myocardial ischaemia (0.6% [n=2] vs 0% [n=0]; P=0.47) did not differ between groups. Conclusions: An oxygenation strategy using high FIO2 compared with conventional FIO2 did not reduce postoperative SSIs in abdominal surgery. No differences in secondary outcomes or adverse events were found.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Aldecoa, CesarHosp Univ Rio Hortega, Dept Anesthesiol & Crit Care, Valladolid, Spain
(author)
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Unzueta, CarmenHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Javier Belda, F.Hosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Librero, JulianUPNA, REDISSEC Red Invest Serv Salud Enfermedades Cron, Complejo Hosp Navarra, Navarrabiomed, Valencia, Spain
(author)
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Tusman, GerardoHosp Privado Comunidad Mar Del Plata, Dept Anesthesiol, Mar Del Plata, Buenos Aires, Argentina
(author)
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Suarez-Sipmann, FernandoUppsala universitet,Hedenstiernalaboratoriet,Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain;Hosp Univ La Princesa, Dept Intens Care, Madrid, Spain(Swepub:uu)fersi946
(author)
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Peiro, SalvadorFdn Fomento Invest Sanitaria & Biomed Comunidad V, Red Invest Serv Salud Enfermedades Cron REDISSEC, Valencia, Spain
(author)
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Pozo, NatividadHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Brunelli, AndreaHosp Germans Tries & Pujol, Dept Anesthesiol & Crit Care, Badalona, Spain
(author)
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Garutti, IgnacioHosp Germans Tries & Pujol, Dept Anesthesiol & Crit Care, Badalona, Spain;Hosp Univ Gen Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Gallego, ClaraHosp Univ Ramon & Cajal, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Rodriguez, AurelioHosp Univ Dr Negrin, Dept Anesthesiol & Crit Care, Las Palmas Gran Canaria, Spain
(author)
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Ignacio Garcia, JoseHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Diaz-Cambronero, OscarHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Balust, JaumeHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Redondo, Francisco J.Hosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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de la Matta, ManuelHosp Univ Virgen del Rocio, Dept Anesthesiol & Crit Care, Seville, Spain
(author)
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Gallego-Ligorit, LuciaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Hernandez, JavierHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Martinez, PascualHosp Albacete, Dept Anesthesiol & Crit Care, Albacete, Spain
(author)
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Perez, AnaHosp Elche, Dept Anesthesiol & Crit Care, Elche, Spain
(author)
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Leal, SonsolesHosp Povisa, Dept Anesthesiol & Crit Care, Vigo, Spain
(author)
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Alday, EnriqueHosp Univ La Princesa, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Monedero, PabloClin Univ Navarra, Dept Anesthesiol & Crit Care, Pamplona, Spain
(author)
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Gonzalez, RafaelHosp Univ Leon, Dept Anesthesiol & Crit Care, Leon, Spain
(author)
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Mazzirani, GuidoHosp Manises, Dept Anesthesiol, Manises, Spain
(author)
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Aguilar, GerardoHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Lopez-Baamonde, ManuelHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Felipe, MarHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Mugarra, AnaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Torrente, JaraHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Valencia, LuciaHosp Univ Dr Negrin, Dept Anesthesiol & Crit Care, Las Palmas Gran Canaria, Spain
(author)
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Varon, VivianaHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Sanchez, SergioHosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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Rodriguez, BenignoHosp Povisa, Dept Anesthesiol & Crit Care, Vigo, Spain
(author)
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Martin, AnaHosp Univ Leon, Dept Anesthesiol & Crit Care, Leon, Spain
(author)
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India, InmaculadaHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Azparren, GonzaloHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Molina, RodrigoHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Villar, JesusInst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain;Hosp Univ Dr Negrin, Res Unit, Multidisciplinary Organ Dysfunct Evaluat Res Netw, Las Palmas Gran Canaria, Spain;St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr Biomed Sci, Toronto, ON, Canada
(author)
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Soro, MarinaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Acosta, JesusHosp Univ Virgen del Rocio, Dept Anesthesiol & Crit Care, Seville, Spain
(author)
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Jose Alberola, MariaHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Alcon, AmaliaHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Almajano, RosaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Alvarez, CarlosHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Anaya, RafaelHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Aragon, CristianHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Argilaga, MartaHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Arocas, BlancaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Ayas, BegonaHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Balandron, VictorHosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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Barcena, ElizabethHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Bejarano, NataliaHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Belmonte, LuisHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Berges, VanesaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Guillen Bermejo, MaHosp Univ Dr Negrin, Dept Anesthesiol & Crit Care, Las Palmas Gran Canaria, Spain
(author)
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Cabadas, RafaelHosp Povisa, Dept Anesthesiol & Crit Care, Vigo, Spain
(author)
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Cabrera, SergioHosp Univ Dr Negrin, Dept Anesthesiol & Crit Care, Las Palmas Gran Canaria, Spain
(author)
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Callejas, RaquelClin Univ Navarra, Dept Anesthesiol & Crit Care, Pamplona, Spain
(author)
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Carbonell, JoseHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Carrizo, JuanHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Castillo, JesusHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Charco, PedroHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Colas, AnaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Colomina, LorenaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Cotter, LauraHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Cruz, PatriciaHosp Univ Gen Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Cuervo, JavierHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Del Castillo, GemaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Del Rio, ElenaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Delgado, JuanHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Dexeus, CarlosHosp Germans Tries & Pujol, Dept Anesthesiol & Crit Care, Badalona, Spain
(author)
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Diaz, RubenHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Dinu, MandalinaHosp Germans Tries & Pujol, Dept Anesthesiol & Crit Care, Badalona, Spain
(author)
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Duca, AlejandroHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Duque, PaulaClin Univ Navarra, Dept Anesthesiol & Crit Care, Pamplona, Spain
(author)
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Echarri, GemmaClin Univ Navarra, Dept Anesthesiol & Crit Care, Pamplona, Spain
(author)
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Fabra, PatriciaHosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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Fernandez, CarmenHosp Univ Gen Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Florea, RalucaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Forcada, PilarHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Fuentes, IsabelHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Garces, CristinaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Garcia Del Valle, SantiagoHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Garcia, BeatrizHosp Univ Gen Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Garcia, EstherHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Garcia, MariaHosp Univ Rio Hortega, Dept Anesthesiol & Crit Care, Valladolid, Spain
(author)
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Garcia, MercedesHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Garrigues, BeatrizHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Gil, FernandoHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Gonzalez, DomingoHosp Univ Virgen del Rocio, Dept Anesthesiol & Crit Care, Seville, Spain
(author)
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Gracia, AlejandroHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Gracia, EstefaniaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Cranell, ManuelHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Guerra, YessicaHosp Univ Rio Hortega, Dept Anesthesiol & Crit Care, Valladolid, Spain
(author)
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Gutierrez, AndreaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Hernando, JuliaHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Herrero, MiriamHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Ibanez, MaiteInst Salud Carlos III, CIBER Enfermedades Resp, Madrid, Spain
(author)
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Imaz, InesHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Izquierdo, BlancaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Jurado, AnaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Lafuente, NoeliaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Lascorz, LauraHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Leon, IreneHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Lopez, AntonioHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Lopez-Herrera, DanielHosp Univ Virgen del Rocio, Dept Anesthesiol & Crit Care, Seville, Spain
(author)
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Lozano, AngelsHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Miguel Marcos, JoseHosp Univ Leon, Dept Anesthesiol & Crit Care, Leon, Spain
(author)
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Martinez, GracielaHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Martinez, SaraHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Mata, EsperanzaHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Matoses, SalomeHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Mendez, RosaHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Merino, MariaHosp Univ Leon, Dept Anesthesiol & Crit Care, Leon, Spain
(author)
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Millaruelo, AndresHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Rodrigo Molina, CarlosHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Monleon, BertaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Mauricio Montenegro, OmarHosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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Luis Munoz, JoseHosp Elche, Dept Anesthesiol & Crit Care, Elche, Spain
(author)
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Oliver-Fornies, PabloHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Ortega, ManuelHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Aranzazu Palencia, MariaHosp Univ Gen Gregorio Maranon, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Parera, AnaHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Pastor, EmestoHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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del Mar Perez, MaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Perez, SaraHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Pestana, DavidHosp Univ Ramon & Cajal, Dept Anesthesiol & Crit Care, Madrid, Spain
(author)
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Pinol, SantiagoHosp Santa Creu & Sant Pau, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Puig, JaumeHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Pujol, RogerHosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain
(author)
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Quesada, NatividadHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Ramon, AnaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Rego, ConsueloHosp Univ Leon, Dept Anesthesiol & Crit Care, Leon, Spain
(author)
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Reviriego, LauraHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Rodriguez, RaycoHosp Univ Dr Negrin, Dept Anesthesiol & Crit Care, Las Palmas Gran Canaria, Spain
(author)
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Romero, BlancaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Romero, EstherHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Rosello, MartaHosp Gen Valencia, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Rovira, LucasHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Ruiz, LolaHosp Univ La Fe, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Sancho, LauraHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Sandin, FranciscoHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Serralta, FerranHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Tres, EvaHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Valls, PaolaHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Vaquero, LauraHosp Fdn Alcorcon, Dept Anesthesiol & Crit Care, Alcorcon, Spain
(author)
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Varela, MarinaHosp Povisa, Dept Anesthesiol & Crit Care, Vigo, Spain
(author)
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Vega, VictorHosp Univ La Princesa, Dept Intens Care, Madrid, Spain
(author)
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Viguera, LauraHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Villazala, RubenHosp Gen Ciudad Real, Dept Anesthesiol & Crit Care, Ciudad Real, Spain
(author)
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Villena, AbigailHosp Clin Univ, Dept Anesthesiol & Crit Care, Valencia, Spain
(author)
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Visiedo, SaraHosp Univ Miguel Servet, Dept Anesthesiol & Crit Care, Zaragoza, Spain
(author)
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Hosp Clin Barcelona, Dept Anesthesiol & Crit Care, Barcelona, Spain;Inst Salud Carlos III, CIBER Enfermedades Resp, Madrid, SpainHosp Univ Rio Hortega, Dept Anesthesiol & Crit Care, Valladolid, Spain
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In:British Journal of Anaesthesia: ELSEVIER SCI LTD124:1, s. 110-1200007-09121471-6771
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