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  • Holmström, Gerd,1951-Uppsala University,Uppsala universitet,Söderberg: Oftalmiatrik (author)

New modifications of Swedish ROP guidelines based on 10-year data from the SWEDROP register

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2019-11-01
  • BMJ,2020
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-401493
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-401493URI
  • https://doi.org/10.1136/bjophthalmol-2019-314874DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-173705URI
  • https://lup.lub.lu.se/record/0742bcfa-207a-4810-8e6f-a3396befd3a5URI
  • https://gup.ub.gu.se/publication/290465URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • BACKGROUND/AIMS:During the last decade, improved neonatal care has resulted in increased survival of the most immature infants and improved health of more mature infants. We hypothesise that this has affected incidence and treatment of retinopathy of prematurity (ROP), enabling guidelines for screening to be modified.METHODS: In Sweden, all infants with gestational age (GA) at birth ≤30 weeks are screened for ROP. Results are registered in a web-based register, Swedish National ROP Register, with a coverage rate of 97%. Incidence of ROP and frequency of treatment, aspects on natural course of ROP and number of examinations, are calculated in relation to GA at birth in infants born during 2008-2017.RESULTS: Of 7249 infants, 31.9% (2310) had ROP and 6.1% (440) were treated. No infant with GA 30 weeks was treated. Incidence of ROP remained similar, but frequency of treatment increased (p=0.023). Over time, GA and birth weight were reduced in infants with ROP and with treated ROP. In the most immature infants, postmenstrual age was lower and postnatal age was higher when any ROP and stage 3 ROP were first detected (p<0.001). At treatment, postmenstrual but not postnatal age of the infant was associated with GA (p<0.001). During the 10-year period, 46 038 examinations were performed.CONCLUSION: Modification of Swedish guidelines is proposed, including only infants with a GA of <30 weeks and postponing the first examination with 1 week in infants with GA 26-29 weeks. This would spare many infants from stressful examinations and reduce eye examinations with at least 20%.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Hellström, Ann,1959Gothenburg University,Göteborgs universitet,University of Gothenburg,Section for Ophthalmology, Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience(Swepub:gu)xheann (author)
  • Gränse, LottaLund University,Lunds universitet,Klinisk forskning kring familjer med ärftliga näthinnesjukdomar,Forskargrupper vid Lunds universitet,Clinical research in families with inherited retinal degeneration,Lund University Research Groups,Department of Clinical Sciences, Ophthalmology, Skåne University Hospital, Lund University, Lund(Swepub:lu)oft-lgr (author)
  • Saric, MarieUmeå University,Umeå universitet,Oftalmiatrik,Department of Clinical Sciences, Ophthalmology, Umeå University, Umeå (author)
  • Sunnqvist, BirgittaDepartment of Ophthalmology, Länssjukhuset Ryhov, Jönköping,Ryhov County Hospital, Jönköping (author)
  • Wallin, AgnetaSt Erik Eye Hospital, Stockholm (author)
  • Tornqvist, KristinaLund University,Lunds universitet,Oftalmologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Ophthalmology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital(Swepub:lu)oft-kto (author)
  • Larsson, Eva,1961-Uppsala University,Uppsala universitet,Söderberg: Oftalmiatrik(Swepub:uu)evalarss (author)
  • Uppsala universitetSöderberg: Oftalmiatrik (creator_code:org_t)

Related titles

  • In:British Journal of Ophthalmology: BMJ104:7, s. 943-9490007-11611468-2079

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