Outcome of PCI with Xience versus other commonly used modern drug eluting stents: a SCAAR report

Grimfjärd, PerUppsala University,Uppsala universitet,Kardiologi,Department of Cardiology, Västerås Hospital, Västerås, Sweden,Västmanland Hospital (author)

Outcome of PCI with Xience versus other commonly used modern drug eluting stents : a SCAAR report

Objectives To analyze the clinical outcome of percutaneous coronary intervention (PCI) using the Xience drug eluting stent (DES) versus other modern DES.Methods This retrospective study based on the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) analyzed the outcome of PCI using Xience versus other commonly used modern DES, 2007 to 2017. The primary outcome measure was a combination of all-cause death, myocardial infarction (MI) and revascularisation with PCI. Angiographical outcome measures were in-stent restenosis (ISR) and stent thrombosis (ST).Results Rates of the primary outcome measure for Xience and other DES were 31.9% and 28.2% respectively, adjusted hazard ratio (HR) 0.99 (95% CI 0.95-1.03). Crude rates of ISR were 2.9% versus 2.1% over 4.3 and 2.9 years respectively, adjusted HR 0.93 (95% CI 0.81-1.06). Crude rates of ST were 0.9% versus 0.7%, adjusted HR 1.07 (95% CI 0.82-1.39). Results were consistent in all sensitivity analyses.Conclusions This nationally complete, real-world study confirms that Xience is a safe and effective DES with low-event rates of ISR and ST. Compared with a control group containing a large proportion of thinner strut stents and absorbable polymers, Xience exhibits similar results in all important clinical endpoint

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
drug eluting stent
PCI
restenosis
stent thrombosis
Cardiology
Kardiologi
drug eluting stent
PCI
restenosis
stent thrombosis

Bergman, ElinUppsala universitet,Centrum för klinisk forskning, Västerås,Department of Cardiology, Västerås Hospital, Västerås, Sweden,Västmanland Hospital (author)
Buccheri, SergioUppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Uppsala University Hospital(Swepub:uu)serbu677 (author)
Erlinge, DavidLund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups(Swepub:lu)kard-der (author)
Lagerqvist, Bo,1952-Uppsala University,Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala University Hospital(Swepub:uu)bolager (author)
Svennblad, BodilUppsala universitet,Uppsala kliniska forskningscentrum (UCR),Uppsala University Hospital(Swepub:uu)bosve677 (author)
Völz, SebastianDepartment of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden (author)
Angerås, OskarDepartment of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden (author)
James, Stefan,1964-Uppsala University,Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR),Uppsala University Hospital(Swepub:uu)stjam367 (author)
Uppsala universitetKardiologi (creator_code:org_t)

In:Catheterization and cardiovascular interventions: Wiley98:2, s. E197-E2041522-19461522-726X

By the author/editor: Grimfjärd, Per; Bergman, Elin; Buccheri, Sergio; Erlinge, David; Lagerqvist, Bo, ...; Svennblad, Bodil; show more...; Völz, Sebastian; Angerås, Oskar; James, Stefan, 1 ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

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