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  • Elshamy, Abdelsamed I.Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan;Natl Res Ctr, Chem Nat Cpds Dept, 33 el Bohouth St, Giza 12622, Egypt (författare)

Recent Advances in Kaempferia Phytochemistry and Biological Activity : A Comprehensive Review

  • Artikel/kapitelEngelska2019

Förlag, utgivningsår, omfång ...

  • 2019-10-07
  • MDPI,2019
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-403539
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-403539URI
  • https://doi.org/10.3390/nu11102396DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:for swepub-publicationtype

Anmärkningar

  • Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely used in traditional medicines to cure metabolic disorders, inflammation, urinary tract infections, fevers, coughs, hypertension, erectile dysfunction, abdominal and gastrointestinal ailments, asthma, wounds, rheumatism, epilepsy, and skin diseases.Objective: Herein, we reported a comprehensive review, including the traditional applications, biological and pharmacological advances, and phytochemical constituents of Kaempheria species from 1972 up to early 2019.Materials and methods: All the information and reported studies concerning Kaempheria plants were summarized from library and digital databases (e.g., Google Scholar, Sci-finder, PubMed, Springer, Elsevier, MDPI, Web of Science, etc.). The correlation between the Kaempheria species was evaluated via principal component analysis (PCA) and agglomerative hierarchical clustering (AHC), based on the main chemical classes of compounds.Results: Approximately 141 chemical constituents have been isolated and reported from Kaempferia species, such as isopimarane, abietane, labdane and clerodane diterpenoids, flavonoids, phenolic acids, phenyl-heptanoids, curcuminoids, tetrahydropyrano-phenolic, and steroids. A probable biosynthesis pathway for the isopimaradiene skeleton is illustrated. In addition, 15 main documented components of volatile oils of Kaempheria were summarized. Biological activities including anticancer, anti-inflammatory, antimicrobial, anticholinesterase, antioxidant, anti-obesity-induced dermatopathy, wound healing, neuroprotective, anti-allergenic, and anti-nociceptive were demonstrated.Conclusions: Up to date, significant advances in phytochemical and pharmacological studies of different Kaempheria species have been witnessed. So, the traditional uses of these plants have been clarified via modern in vitro and in vivo biological studies. In addition, these traditional uses and reported biological results could be correlated via the chemical characterization of these plants. All these data will support the biologists in the elucidation of the biological mechanisms of these plants.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Mohamed, Tarik A.Natl Res Ctr, Chem Med Plants Dept, 33 El Bohouth St, Giza 12622, Egypt (författare)
  • Essa, Ahmed F.Natl Res Ctr, Chem Nat Cpds Dept, 33 el Bohouth St, Giza 12622, Egypt (författare)
  • Abd-El Gawad, Ahmed M.Mansoura Univ, Dept Bot, Fac Sci, Mansoura 35516, Egypt;King Saud Univ, Plant Prod Dept, Coll Food Agr Sci, Riyadh 11451, Saudi Arabia (författare)
  • Alqahtani, Ali S.King Saud Univ, Dept Pharmacognosy, Coll Pharm, POB 2457, Riyadh 11451, Saudi Arabia (författare)
  • Shahat, Abdelaaty A.Natl Res Ctr, Chem Med Plants Dept, 33 El Bohouth St, Giza 12622, Egypt;King Saud Univ, Dept Pharmacognosy, Coll Pharm, POB 2457, Riyadh 11451, Saudi Arabia (författare)
  • Yoneyama, TatsuroTokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan (författare)
  • Farrag, Abdel Razik H.Natl Res Ctr, Pathol Dept, Giza 12622, Egypt (författare)
  • Noji, Masaaki (författare)
  • El-Seedi, HeshamUppsala universitet,Farmakognosi,Menoufia Univ, Dept Chem, Fac Sci, Shibin Al Kawm 32512, Egypt;Jiangsu Univ, Coll Food & Biol Engn, Zhenjiang 212013, Jiangsu, Peoples R China(Swepub:uu)heels173 (författare)
  • Umeyama, AkemiTokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan (författare)
  • Pare, Paul W.Texas Tech Univ, Dept Chem Biochem, Lubbock, TX 79409 USA (författare)
  • Hegazy, Mohamed-Elamir F.Natl Res Ctr, Chem Med Plants Dept, 33 El Bohouth St, Giza 12622, Egypt;Johannes Gutenberg Univ Mainz, Inst Pharm & Biochem, Dept Pharmaceut Biol, Staudinger Weg 5, D-55128 Mainz, Germany (författare)
  • Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan;Natl Res Ctr, Chem Nat Cpds Dept, 33 el Bohouth St, Giza 12622, EgyptNatl Res Ctr, Chem Med Plants Dept, 33 El Bohouth St, Giza 12622, Egypt (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Nutrients: MDPI11:102072-6643

Internetlänk

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  • Nutrients (Sök värdpublikationen i LIBRIS)

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