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Cost-effectiveness ...
Cost-effectiveness of an indicated preventive intervention for depression in adolescents: a model to support decision making
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- Ssegonja, Richard (författare)
- Uppsala universitet,Socialmedicin/CHAP,Department of Public Health and Caring Sciences, Child Health and Parenting (CHAP), Uppsala University, Uppsala, Sweden
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- Sampaio, Filipa, PhD, 1985- (författare)
- Uppsala universitet,Socialmedicin/CHAP,Department of Public Health and Caring Sciences, Child Health and Parenting (CHAP), Uppsala University, Uppsala, Sweden
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- Alaie, Iman (författare)
- Uppsala universitet,Barn- och ungdomspsykiatri,Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden
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- Philipson, Anna, 1978- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,University Health Care Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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- Hagberg, Lars, 1956- (författare)
- Örebro universitet,Institutionen för hälsovetenskaper,Region Örebro län,University Health Care Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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- Krahn, Murray (författare)
- Toronto Health Economics and Technology Assessment (THETA) Collaborative, Toronto, Canada
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- Sarkadi, Anna, Professor, 1974- (författare)
- Uppsala universitet,Socialmedicin/CHAP,Department of Public Health and Caring Sciences, Child Health and Parenting (CHAP), Uppsala University, Uppsala, Sweden; Murdoch Children's Research Institute, Melbourne, Australia
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- Langenskiöld, Sophie, 1968- (författare)
- Uppsala universitet,Hälsoekonomi,Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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- Jonsson, Ulf, 1974- (författare)
- Karolinska Institutet,Uppsala universitet,Barn- och ungdomspsykiatri,Department of Neuroscience, Child and Adolescent Psychiatry, Uppsala University, Uppsala, Sweden; Center of Neurodevelopmental Disorders at Karolinska Institutet (KIND), Pediatric Neuropsychiatry Unit, Sweden; Centre for Psychiatry Research, Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden
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- Feldman, Inna, Docent, 1951- (författare)
- Uppsala universitet,Socialmedicin/CHAP,Department of Public Health and Caring Sciences, Child Health and Parenting (CHAP), Uppsala University, Uppsala, Sweden
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(creator_code:org_t)
- Elsevier, 2020
- 2020
- Engelska.
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Ingår i: Journal of Affective Disorders. - : Elsevier. - 0165-0327 .- 1573-2517. ; 277, s. 789-799
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Adolescent depression has negative health and economic outcomes in the shortand long-term. Indicated preventive interventions, in particular group based cognitive behavioural therapy (GB-CBT), are ef-fective in preventing depression in adolescents with subsyndromal depression. However, little is known about the cost-effectiveness of these interventions. Methods: A Markov cohort model was used to conduct cost-effectiveness analyses comparing a GB-CBT indicated preventive intervention for depression, to a no-intervention option in a Swedish setting. Taking a time horizon of 5and 10 years, incremental differences in societal costs and health benefits expressed as differences in the proportion of cases of depression prevented, and as quality adjusted life years (QALYs) gained were estimated. Through univariate and probabilistic sensitivity analyses, the robustness of the results was explored. Costs, presented in 2018 USD, and effects were discounted at a yearly rate of 3%. Results: The base-case analysis showed that GB-CBT indicated preventive intervention incurred lower costs, prevented a larger proportion of cases of depression and generated higher QALYs compared to the no -intervention option for both time horizons. Offering the intervention was even a cost saving strategy and demonstrated a probability of being cost-effective of over 95%. In the sensitivity analyses, these results were robust to the modelling assumptions. Limitations: The study considered a homogeneous cohort and assumed a constant annual decay rate of the relative treatment effect. Conclusions: GB-CBT indicated preventive interventions for depression in adolescence can generate good value for money compared to leaving adolescents with subsyndromal depression untreated.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Nyckelord
- Adolescence
- Depression
- Direct costs
- Indirect costs
- markov model
- and sensitivity analysis.
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Ssegonja, Richar ...
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Sampaio, Filipa, ...
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Alaie, Iman
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Philipson, Anna, ...
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Hagberg, Lars, 1 ...
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Krahn, Murray
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Sarkadi, Anna, P ...
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Langenskiöld, So ...
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Jonsson, Ulf, 19 ...
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Feldman, Inna, D ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Psykiatri
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Omvårdnad
- Artiklar i publikationen
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Journal of Affec ...
- Av lärosätet
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Uppsala universitet
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Örebro universitet
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Karolinska Institutet