WFRF:(Li Hao 1984 )
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- Kämpfe Nordström, CharlottaUppsala universitet,Öron-, näs- och halssjukdomar (author)
A Micro-CT and Synchrotron Imaging Study of the Human Endolymphatic Duct with Special Reference to Endolymph Outflow and Meniere's Disease
- Article/chapterEnglish2020
Publisher, publication year, extent ...
- 2020-05-19
- Springer Science and Business Media LLC,2020
- electronicrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-406752
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-406752URI
- https://doi.org/10.1038/s41598-020-65110-0DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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- De tre sista författarna delar sistaförfattarskapet
- Meniere’s disease remains enigmatic, and has no treatment with sufficient evidence. The characteristic histopathological finding is endolymphatic hydrops, suggesting either an overproduction or decreased reabsorption of endolymph in the human inner ear. This study presents the first analysis of the vascular plexus around the human endolymphatic duct using micro computed tomography and coherent synchrotron radiation with phase contrast imaging. Using a software program, data were processed by volume-rendering with scalar opacity mapping to create transparent three-dimensional reconstructions. A rich vascular plexus was discovered around the endolymphatic duct that drained into collecting channels, linked to the vestibular venous outflow system. This network is believed to make up the principal route for endolymph outflow, and its associated malfunction may result in endolymphatic hydrops and Meniere’s disease.
Subject headings and genre
- TEKNIK OCH TEKNOLOGIER Medicinteknik Medicinsk bildbehandling hsv//swe
- ENGINEERING AND TECHNOLOGY Medical Engineering Medical Image Processing hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinsk bioteknologi Biomedicinsk laboratorievetenskap/teknologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Medical Biotechnology Biomedical Laboratory Science/Technology hsv//eng
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- Li, Hao,1984-Uppsala universitet,Öron-, näs- och halssjukdomar(Swepub:uu)haoli805 (author)
- Ladak, Hanif M. (author)
- Agrawal, Sumit (author)
- Rask-Andersen, HelgeUppsala universitet,Öron-, näs- och halssjukdomar(Swepub:uu)helgraan (author)
- Uppsala universitetÖron-, näs- och halssjukdomar (creator_code:org_t)
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- In:Scientific Reports: Springer Science and Business Media LLC10:12045-2322
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