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- Partel, GabrieleUppsala universitet,Avdelningen för visuell information och interaktion,Science for Life Laboratory, SciLifeLab (author)
Identification of spatial compartments in tissue from in situ sequencing data
- BookEnglish2024
Publisher, publication year, extent ...
- Cold Spring Harbor Laboratory,2024
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-410215
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-410215URI
- https://doi.org/10.1101/765842DOI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- Spatial organization of tissue characterizes biological function, and spatially resolved gene expression has the power to reveal variations of features with high resolution. Here, we propose a novel graph-based in situ sequencing decoding approach that improves recall, enabling precise spatial gene expression analysis. We apply our method on in situ sequencing data from mouse brain sections, identify spatial compartments that correspond with known brain regions, and relate them with tissue morphology.
Subject headings and genre
- NATURVETENSKAP Data- och informationsvetenskap Bioinformatik hsv//swe
- NATURAL SCIENCES Computer and Information Sciences Bioinformatics hsv//eng
- TEKNIK OCH TEKNOLOGIER Elektroteknik och elektronik Signalbehandling hsv//swe
- ENGINEERING AND TECHNOLOGY Electrical Engineering, Electronic Engineering, Information Engineering Signal Processing hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
- in situ sequencing
- spatial omics
Added entries (persons, corporate bodies, meetings, titles ...)
- Hilscher, Markus M.Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University (author)
- Giorgia, MilliUppsala universitet,Avdelningen för visuell information och interaktion (author)
- Solorzano, Leslie,1989-Uppsala universitet,Avdelningen för visuell information och interaktion,Science for Life Laboratory, SciLifeLab(Swepub:uu)lesso657 (author)
- Klemm, Anna HUppsala universitet,Avdelningen för visuell information och interaktion,Science for Life Laboratory, SciLifeLab(Swepub:uu)annkl878 (author)
- Nilsson, MatsScience for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University (author)
- Wählby, Carolina,professor,1974-Uppsala universitet,Avdelningen för visuell information och interaktion,Science for Life Laboratory, SciLifeLab(Swepub:uu)cli05194 (author)
- Uppsala universitetAvdelningen för visuell information och interaktion (creator_code:org_t)
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