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Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia

Dewey, Marc (författare)
Charite Univ Med Berlin, Dept Radiol, Berlin, Germany; Berlin Inst Hlth, Berlin, Germany; DZHK German Ctr Cardiovasc Res Partner Site, Berlin, Germany;
Siebes, Maria (författare)
Univ Amsterdam, Med Ctr, Dept Biomed Engn & Phys Translat Physiol, Amsterdam, Netherlands
Kachelrieß, Marc (författare)
German Canc Res Ctr, Div Xray Imaging & CT, Heidelberg, Germany
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Kofoed, Klaus F (författare)
Univ Copenhagen, Rigshosp, Dept Cardiol & radiol, Ctr Heart, Copenhagen, Denmark
Maurovich-Horvat, Pál (författare)
Semmelwe Univ, Heart & Vasc Ctr, MTA SE Cardiovasc Imaging Res Grp, Budapest, Hungary
Nikolaou, Konstantin (författare)
Univ Klinikum Tubingen, Radiol Klin, Diagnost & Intervent Radiol, Tubingen, Germany
Bai, Wenjia (författare)
Imperial Coll London, Dept Comp, Biomed Image Anal Grp, London, England
Kofler, Andreas (författare)
Charite Univ Med Berlin, Dept Radiol, Berlin, Germany
Manka, Robert (författare)
Univ Zurich, Univ Zurich Hosp, Inst Diagnost & Intervent Radiol, Zurich, Switzerland; Univ Zurich, Univ Zurich Hosp, Dept Cardiol, Zurich, Switzerland ;Univ Zurich, Inst Biomed Engn, Zurich, Switzerland; Swiss Fed Inst Technol, Zurich, Switzerland
Kozerke, Sebastian (författare)
Univ Zurich, Inst Biomed Engn, Zurich, Switzerland; Swiss Fed Inst Technol, Zurich, Switzerland
Chiribiri, Amedeo (författare)
Kings Coll London, Sch Biomed Engn & Imaging Sci, Dept Cardiovasc Imaging, London, England
Schaeffter, Tobias (författare)
Kings Coll London, Sch Biomed Engn & Imaging Sci, Dept Cardiovasc Imaging, London, England; Phys Tech Bundesanstalt, Med Phys & Metrol Informat Technol, Berlin, Germany
Michallek, Florian (författare)
Charite Univ Med Berlin, Dept Radiol, Berlin, Germany
Bengel, Frank (författare)
Hannover Med Sch, Klin Nukl Med, Hannover, Germany
Nekolla, Stephan (författare)
Tech Univ Munich, Klinikum Rechts Isar, Nukl Med Klin & Poliklin, DZHK German Ctr Cardiovasc Res,Partner Site Munic, Munich, Germany
Knaapen, Paul (författare)
Vrije Univ Amsterdam Med Ctr, Dept Cardiol, Amsterdam, Netherlands
Lubberink, Mark (författare)
Uppsala universitet,Radiologi,Uppsala Univ Hosp, Med Phys, Uppsala, Sweden
Senior, Roxy (författare)
Royal Brompton Hosp London, Dept Cardiol, London, England
Tang, Meng-Xing (författare)
Imperial Coll London, Dept Bioengn, London, England
Piek, Jan J (författare)
Univ Amsterdam, Heart Ctr, Med Ctr, Amsterdam, Netherlands
van de Hoef, Tim (författare)
Univ Amsterdam, Heart Ctr, Med Ctr, Amsterdam, Netherlands
Martens, Johannes (författare)
Wurzburg Univ Clin, Comprehens Heart Failure Ctr, Dept Cellular & Mol Imaging, Wurzburg, Germany
Schreiber, Laura (författare)
Wurzburg Univ Clin, Comprehens Heart Failure Ctr, Dept Cellular & Mol Imaging, Wurzburg, Germany
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 (creator_code:org_t)
2020-02-24
2020
Engelska.
Ingår i: Nature Reviews Cardiology. - : Springer Nature. - 1759-5002 .- 1759-5010. ; 17:7, s. 427-450
Relaterad länk:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://www.nature.c...
https://urn.kb.se/re...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic heart disease. SPECT is most commonly used for clinical myocardial perfusion imaging, whereas PET is the clinical reference standard for the quantification of myocardial perfusion. MRI does not involve exposure to ionizing radiation, similar to echocardiography, which can be performed at the bedside. CT perfusion imaging is not frequently used but CT offers coronary angiography data, and invasive catheter-based methods can measure coronary flow and pressure. Technical improvements to the quantification of pathophysiological parameters of myocardial ischaemia can be achieved. Clinical consensus recommendations on the appropriateness of each technique were derived following a European quantitative cardiac imaging meeting and using a real-time Delphi process. SPECT using new detectors allows the quantification of myocardial blood flow and is now also suited to patients with a high BMI. PET is well suited to patients with multivessel disease to confirm or exclude balanced ischaemia. MRI allows the evaluation of patients with complex disease who would benefit from imaging of function and fibrosis in addition to perfusion. Echocardiography remains the preferred technique for assessing ischaemia in bedside situations, whereas CT has the greatest value for combined quantification of stenosis and characterization of atherosclerosis in relation to myocardial ischaemia. In patients with a high probability of needing invasive treatment, invasive coronary flow and pressure measurement is well suited to guide treatment decisions. In this Consensus Statement, we summarize the strengths and weaknesses as well as the future technological potential of each imaging modality.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

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