Sökning: WFRF:(Robien Mark A.) >
Anthropometric Risk...
Anthropometric Risk Factors for Cancers of the Biliary Tract in the Biliary Tract Cancers Pooling Project
-
- Jackson, Sarah S. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Van Dyke, Alison L. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Zhu, Bin (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
visa fler...
-
- Pfeiffer, Ruth M. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Petrick, Jessica L. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Adami, Hans-Olov (författare)
- Karolinska Institutet
-
- Albanes, Demetrius (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Andreotti, Gabriella (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Freeman, Laura E. Beane (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- de Gonzalez, Amy Berrington (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Buring, Julie E. (författare)
- Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.
-
- Chan, Andrew T. (författare)
- Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.;Massachusetts Gen Hosp, Dept Med, Div Gastroenterol, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.
-
- Chen, Yu (författare)
- NYU, Sch Med, Dept Populat Hlth, New York, NY USA.;NYU, Sch Med, Perlmutter Canc Ctr, New York, NY USA.
-
- Fraser, Gary E. (författare)
- Loma Linda Univ, Sch Publ Hlth, Loma Linda, CA 92350 USA.
-
- Freedman, Neal D. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Gao, Yu-Tang (författare)
- Shanghai Canc Inst, Dept Epidemiol, Shanghai, Peoples R China.
-
- Gapstur, Susan M. (författare)
- Amer Canc Soc Inc, Behav & Epidemiol Res Grp, Atlanta, GA USA.
-
- Gaziano, J. Michael (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.;Boston Veteran Affairs Healthcare Syst, Boston, MA USA.
-
- Giles, Graham G. (författare)
- Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Parkville, Vic, Australia.
-
- Grant, Eric J. (författare)
- Radiat Effects Res Fdn, Dept Epidemiol, Hiroshima, Japan.
-
- Grodstein, Francine (författare)
- Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.
-
- Hartge, Patricia (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Jenab, Mazda (författare)
- WHO, IARC, Sec Nutr & Metab, Lyon, France.
-
- Kitahara, Cari M. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Knutsen, Synnove F. (författare)
- Loma Linda Univ, Sch Publ Hlth, Loma Linda, CA 92350 USA.
-
- Koh, Woon-Puay (författare)
- Duke NUS Med Sch, Hlth Serv & Syst Res, Singapore, Singapore.;Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore, Singapore.
-
- Larsson, Susanna C. (författare)
- Karolinska Institutet
-
- Lee, I-Min (författare)
- Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.
-
- Liao, Linda M. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Luo, Juhua (författare)
- Indiana Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Bloomington, IN USA.
-
- McGee, Emma E. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Milne, Roger L. (författare)
- Canc Council Victoria, Canc Epidemiol Div, Melbourne, Vic, Australia.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Ctr Epidemiol & Biostat, Parkville, Vic, Australia.
-
- Monroe, Kristine R. (författare)
- Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA 90033 USA.
-
- Neuhouser, Marian L. (författare)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Canc Prevent Program, 1124 Columbia St, Seattle, WA 98104 USA.
-
- O'Brien, Katie M. (författare)
- NIEHS, Epidemiol Branch, POB 12233, Res Triangle Pk, NC 27709 USA.
-
- Peters, Ulrike (författare)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Canc Prevent Program, 1124 Columbia St, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
-
- Poynter, Jenny N. (författare)
- Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
-
- Purdue, Mark P. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Robien, Kim (författare)
- George Washington Univ, Milken Inst Sch Publ Hlth, Exercise & Nutr Sci, Washington, DC USA.
-
- Sandler, Dale P. (författare)
- NIEHS, Epidemiol Branch, POB 12233, Res Triangle Pk, NC 27709 USA.
-
- Sawada, Norie (författare)
- Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan.
-
- Schairer, Catherine (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Sesso, Howard D. (författare)
- Harvard TH Chan Sch Publ Hlth, Dept Epidemiol, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Div Prevent Med, 75 Francis St, Boston, MA 02115 USA.
-
- Simon, Tracey G. (författare)
- Massachusetts Gen Hosp, Dept Med, Div Gastroenterol, Boston, MA 02114 USA.;Massachusetts Gen Hosp, Clin & Translat Epidemiol Unit, Boston, MA 02114 USA.;Harvard Med Sch, Boston, MA 02115 USA.
-
- Sinha, Rashmi (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Stolzenberg-Solomon, Rachael Z. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Tsugane, Shoichiro (författare)
- Natl Canc Ctr, Ctr Publ Hlth Sci, Epidemiol & Prevent Grp, Tokyo, Japan.
-
- Wang, Renwei (författare)
- Univ Pittsburgh, UPMC Hillman Canc Ctr, Pittsburgh, PA USA.
-
- Weiderpass, Elisabete (författare)
- IARC, Lyon, France.
-
- Weinstein, Stephanie J. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- White, Emily (författare)
- Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
-
- Wolk, Alicja (författare)
- Karolinska Institutet
-
- Yuan, Jian-Min (författare)
- Univ Pittsburgh, UPMC Hillman Canc Ctr, Pittsburgh, PA USA.;Univ Pittsburgh, Grad Sch Publ Hlth, Dept Epidemiol, Pittsburgh, PA 15260 USA.
-
- Zeleniuch-Jacquotte, Anne (författare)
- NYU, Sch Med, Dept Populat Hlth, New York, NY USA.;NYU, Sch Med, Perlmutter Canc Ctr, New York, NY USA.
-
- Zhang, Xuehong (författare)
- Brigham & Womens Hosp, Dept Med, Channing Div Network Med, 75 Francis St, Boston, MA 02115 USA.
-
- McGlynn, Katherine A. (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
- Campbell, Peter T. (författare)
- Amer Canc Soc Inc, Behav & Epidemiol Res Grp, Atlanta, GA USA.
-
- Koshiol, Jill (författare)
- NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
-
visa färre...
-
Karolinska Institutet NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA (creator_code:org_t)
- AMER ASSOC CANCER RESEARCH, 2019
- 2019
- Engelska.
-
Ingår i: Cancer Research. - : AMER ASSOC CANCER RESEARCH. - 0008-5472 .- 1538-7445. ; 79:15, s. 3973-3982
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- Biliary tract cancers are rare but highly fatal with poorly understood etiology. Identifying potentially modifiable risk factors for these cancers is essential for prevention. Here we estimated the relationship between adiposity and cancer across the biliary tract, including cancers of the gallbladder (GBC), intrahepatic bile ducts (IHBDC), extrahepatic bile ducts (EHBDC), and the ampulla of Vater (AVC). We pooled data from 27 prospective cohorts with over 2.7 million adults. Adiposity was measured using baseline body mass index (BMI), waist circumference, hip circumference, waist-to-hip, and waist-to-height ratios. HRs and 95% confidence intervals (95% CI) were estimated using Cox proportional hazards models adjusted for sex, education, race, smoking, and alcohol consumption with age as the time metric and the baseline hazard stratified by study. During 37,883,648 person-years of follow-up, 1,343 GBC cases, 1,194 EHBDC cases, 784 IHBDC cases, and 623 AVC cases occurred. For each 5 kg/m(2) increase in BMI, there were risk increases for GBC (HR = 1.27; 95% CI, 1.19-1.36), IHBDC (HR = 1.32; 95% CI, 1.21-1.45), and EHBDC (HR = 1.13; 95% CI, 1.03-1.23), but not AVC (HR = 0.99; 95% CI, 0.88-1.11). Increasing waist circumference, hip circumference, waist-to-hip ratio, and waist-to-height ratio were associated with GBC and IHBDC but not EHBDC or AVC. These results indicate that adult adiposity is associated with an increased risk of biliary tract cancer, particularly GBC and IHBDC. Moreover, they provide evidence for recommending weight maintenance programs to reduce the risk of developing these cancers. Significance: These findings identify a correlation between adiposity and biliary tract cancers, indicating that weight management programs may help minimize the risk of these diseases.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Jackson, Sarah S ...
-
Van Dyke, Alison ...
-
Zhu, Bin
-
Pfeiffer, Ruth M ...
-
Petrick, Jessica ...
-
Adami, Hans-Olov
-
visa fler...
-
Albanes, Demetri ...
-
Andreotti, Gabri ...
-
Freeman, Laura E ...
-
de Gonzalez, Amy ...
-
Buring, Julie E.
-
Chan, Andrew T.
-
Chen, Yu
-
Fraser, Gary E.
-
Freedman, Neal D ...
-
Gao, Yu-Tang
-
Gapstur, Susan M ...
-
Gaziano, J. Mich ...
-
Giles, Graham G.
-
Grant, Eric J.
-
Grodstein, Franc ...
-
Hartge, Patricia
-
Jenab, Mazda
-
Kitahara, Cari M ...
-
Knutsen, Synnove ...
-
Koh, Woon-Puay
-
Larsson, Susanna ...
-
Lee, I-Min
-
Liao, Linda M.
-
Luo, Juhua
-
McGee, Emma E.
-
Milne, Roger L.
-
Monroe, Kristine ...
-
Neuhouser, Maria ...
-
O'Brien, Katie M ...
-
Peters, Ulrike
-
Poynter, Jenny N ...
-
Purdue, Mark P.
-
Robien, Kim
-
Sandler, Dale P.
-
Sawada, Norie
-
Schairer, Cather ...
-
Sesso, Howard D.
-
Simon, Tracey G.
-
Sinha, Rashmi
-
Stolzenberg-Solo ...
-
Tsugane, Shoichi ...
-
Wang, Renwei
-
Weiderpass, Elis ...
-
Weinstein, Steph ...
-
White, Emily
-
Wolk, Alicja
-
Yuan, Jian-Min
-
Zeleniuch-Jacquo ...
-
Zhang, Xuehong
-
McGlynn, Katheri ...
-
Campbell, Peter ...
-
Koshiol, Jill
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
- Artiklar i publikationen
-
Cancer Research
- Av lärosätet
-
Uppsala universitet
-
Karolinska Institutet