WFRF:(Glynn Anders)
Search: WFRF:(Glynn Anders) > (2015-2019) > Dietary exposure to...
- 8 of 35
- Previous record
- Next record
- To hitlist
- Bergkvist, CharlotteKarolinska Inst, Inst Environm Med, POB 210, SE-17177 Stockholm, Sweden. (author)
Dietary exposure to polychlorinated biphenyls and risk of myocardial infarction in men - A population-based prospective cohort study
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- PERGAMON-ELSEVIER SCIENCE LTD,2016
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:uu-419415
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-419415URI
- https://doi.org/10.1016/j.envint.2015.11.020DOI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:133082569URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Background: Major food contaminants such as polychlorinated biphenyls (PCBs) are proposed to play a role in the etiology of cardiovascular disease (CVD), but to date the impact of PCBs on cardiovascular health need to be explored. Methods and results: We assessed the association between validated food frequency questionnaire-based estimates of dietary PCB exposure and risk of myocardial infarction, ascertained through register-linkage, among 36,759 men from the population-based Swedish Cohort of Men, free of cardiovascular disease, diabetes and cancer at baseline (1997). Relative risks were adjusted for known cardiovascular risk factors, long-chain omega-3 fatty acids (eicosapentaenoic and docosahexaenoic acids) and methyl mercury exposure. During 12 years of follow-up (433,243 person-years), we ascertained 3005 incident cases of myocardial infarction (654 fatal). Compared with the lowest quintile of dietary PCB exposure (median 113 ng/day), men in the highest quintile (median 436 ng/day) had multivariable-adjusted relative risks of 1.74 (95% confidence interval [CI], 1.30-2.33; p-trend < 0.001) for total and 1.97 (95% C11.42-2.75; p-trend < 0.001) for non-fatal myocardial infarction. In mutually adjusted models, dietary PCB exposure was associated with an increased risk of myocardial infarction, while the intake of long-chain omega-3 fish fatty acids was associated with a decreased risk. We also observed an effect modification by adiposity on the association between of dietary PCB exposure and myocardial infarction, with higher risk among lean men (p value for interaction = 0.03). Conclusions: Exposure to PCBs via diet was associated with increased risk of myocardial infarction in men. (C) 2015 Elsevier Ltd. All rights reserved.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Arbetsmedicin och miljömedicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Health Sciences Occupational Health and Environmental Health hsv//eng
- PCB
- Myocardial infarction
- Dietary
- Epidemiology
- Prospective cohort
- Population-based
- n-3 fish fatty acids
Added entries (persons, corporate bodies, meetings, titles ...)
- Berglund, MarikaKarolinska Institutet (author)
- Glynn, AndersNatl Food Agcy, Risk & Benefit Assessment Dept, Uppsala, Sweden. (author)
- Julin, BettinaKarolinska Inst, Inst Environm Med, POB 210, SE-17177 Stockholm, Sweden. (author)
- Wolk, AlicjaKarolinska Institutet (author)
- Akesson, AgnetaKarolinska Institutet (author)
- Karolinska InstitutetKarolinska Inst, Inst Environm Med, POB 210, SE-17177 Stockholm, Sweden. (creator_code:org_t)
Related titles
- In:Environment International: PERGAMON-ELSEVIER SCIENCE LTD88, s. 9-140160-41201873-6750
Internet link
Find in a library
- Environment International (Search for host publication in LIBRIS)
To the university's database
- 8 of 35
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Bergkvist, Charl ...
- Berglund, Marika
- Glynn, Anders
- Julin, Bettina
- Wolk, Alicja
- Akesson, Agneta
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Health Sciences
- and Occupational Hea ...
- Articles in the publication
- Environment Inte ...
- By the university
- Uppsala University
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
