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Anthropometry and h...
Anthropometry and head and neck cancer : a pooled analysis of cohort data
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- Gaudet, Mia M. (författare)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30316 USA.
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- Kitahara, Cari M. (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Newton, Christina C. (författare)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30316 USA.
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- Bernstein, Leslie (författare)
- City Hope Natl Med Ctr, Beckman Res Inst, Dept Populat Sci, Div Canc Etiol, Duarte, CA USA.
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- Reynolds, Peggy (författare)
- Univ Calif Berkeley, Canc Prevent Inst, Berkeley, CA 94720 USA.
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- Weiderpass, Elisabete (författare)
- Karolinska Institutet
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- Kreimer, Aimee R. (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Yang, Gong (författare)
- Vanderbilt Ingram Canc Ctr, Dept Med, Div Epidemiol, Nashville, TN USA.
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- Adami, Hans-Olov (författare)
- Karolinska Institutet
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- Alavanja, Michael C. (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Freeman, Laura E. Beane (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Boeing, Heiner (författare)
- German Inst Human Nutr, Dept Epidemiol, Potsdam, Germany.
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- Buring, Julie (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.
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- Chaturvedi, Anil (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Chen, Yu (författare)
- NYU Sch Med, Dept Populat Hlth, New York, NY USA.;NYU Sch Med, Laura & Isaac Perlmutter Canc Ctr, New York, NY USA.
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- D'Aloisio, Aimee A. (författare)
- Social & Sci Syst, Durham, NC USA.
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- Freedman, Michal (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Gao, Yu-Tang (författare)
- Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Epidemiol,Shanghai Canc Inst, Shanghai 200030, Peoples R China.
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- Gaziano, J. Michael (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Brigham & Womens Hosp, Dept Med, Div Aging, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Vet Affairs Boston Healthcare Syst, Boston, MA USA.
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- Giles, Graham G. (författare)
- Univ Melbourne, Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic 3010, Australia.;Univ Melbourne, Ctr Biostat & Epidemiol, Melbourne, Vic 3010, Australia.
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- Hakansson, Niclas (författare)
- Karolinska Institutet
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- Huang, Wen-Yi (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Lee, I-Min (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.
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- Linet, Martha S. (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- MacInnis, Robert J. (författare)
- Univ Melbourne, Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic 3010, Australia.;Univ Melbourne, Ctr Biostat & Epidemiol, Melbourne, Vic 3010, Australia.
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- Park, Yikyung (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.;Washington Univ, Sch Med, Div Publ Hlth Sci, St Louis, MO USA.
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- Prizment, Anna (författare)
- Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA.
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- Purdue, Mark P. (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.;Ontario Inst Canc Res, Toronto, ON, Canada.
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- Riboli, Elio (författare)
- Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Dept Epidemiol & Biostat, London, England.
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- Robien, Kim (författare)
- George Washington Univ, Dept Epidemiol & Biostat, Washington, DC USA.
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- Sandler, Dale P. (författare)
- Natl Inst Environm Hlth Sci, Epidemiol Branch, Res Triangle Pk, NC USA.
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- Schairer, Catherine (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Sesso, Howard D. (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Brigham & Womens Hosp, Dept Med, Div Aging, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.
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- Shu, Xiao Ou (författare)
- Vanderbilt Ingram Canc Ctr, Dept Med, Div Epidemiol, Nashville, TN USA.
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- White, Emily (författare)
- Fred Hutchinson Canc Res Ctr, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
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- Wolk, Alicja (författare)
- Karolinska Institutet
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- Xiang, Yong-Bing (författare)
- Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Dept Epidemiol,Shanghai Canc Inst, Shanghai 200030, Peoples R China.
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- Zelenuich-Jacquotte, Anne (författare)
- NYU Sch Med, Dept Populat Hlth, New York, NY USA.;NYU Sch Med, Laura & Isaac Perlmutter Canc Ctr, New York, NY USA.
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- Zheng, Wei (författare)
- Vanderbilt Ingram Canc Ctr, Dept Med, Div Epidemiol, Nashville, TN USA.
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- Patel, Alpa V. (författare)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30316 USA.
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- Hartge, Patricia (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- de Gonzalez, Amy Berrington (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA.
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- Gapstur, Susan M. (författare)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30316 USA.
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Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30316 USA NCI, Div Canc Epidemiol & Genet, NIH, US Dept HHS, Bethesda, MD 20892 USA. (creator_code:org_t)
- 2015-06-06
- 2015
- Engelska.
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Ingår i: International Journal of Epidemiology. - : OXFORD UNIV PRESS. - 0300-5771 .- 1464-3685. ; 44:2, s. 673-681
- Relaterad länk:
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https://academic.oup...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Associations between anthropometry and head and neck cancer (HNC) risk are inconsistent. We aimed to evaluate these associations while minimizing biases found in previous studies. Methods: We pooled data from 1 941 300 participants, including 3760 cases, in 20 cohort studies and used multivariable-adjusted Cox proportional hazard regression models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association of anthropometric measures with HNC risk overall and stratified by smoking status. Results: Greater waist circumference (per 5cm: HR = 1.04, 95% CI 1.03-1.05, P-value for trend = <0.0001) and waist-to-hip ratio (per 0.1 unit: HR = 1.07, 95% CI 1.05-1.09, P-value for trend = <0.0001), adjusted for body mass index (BMI), were associated with higher risk and did not vary by smoking status (P-value for heterogeneity = 0.85 and 0.44, respectively). Associations with BMI (P-value for interaction = <0.0001) varied by smoking status. Larger BMI was associated with higher HNC risk in never smokers (per 5 kg/m(2): HR = 1.15, 95% CI 1.06-1.24, P-value for trend = 0.0006), but not in former smokers (per 5 kg/m(2): HR = 0.99, 95% CI 0.93-1.06, P-value for trend = 0.79) or current smokers (per 5 kg/m(2): HR = 0.76, 95% CI 0.71-0.82, P-value for trend = <0.0001). Larger hip circumference was not associated with a higher HNC risk. Greater height (per 5cm) was associated with higher risk of HNC in never and former smokers, but not in current smokers. Conclusions: Waist circumference and waist-to-hip ratio were associated positively with HNC risk regardless of smoking status, whereas a positive association with BMI was only found in never smokers.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Head and neck neoplasms
- obesity
- smoking
- waist-hip ratio
- waist circumference
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- Av författaren/redakt...
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Gaudet, Mia M.
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Kitahara, Cari M ...
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Newton, Christin ...
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Bernstein, Lesli ...
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Reynolds, Peggy
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Weiderpass, Elis ...
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visa fler...
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Kreimer, Aimee R ...
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Yang, Gong
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Adami, Hans-Olov
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Alavanja, Michae ...
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Freeman, Laura E ...
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Boeing, Heiner
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Buring, Julie
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Chaturvedi, Anil
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Chen, Yu
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D'Aloisio, Aimee ...
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Freedman, Michal
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Gao, Yu-Tang
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Gaziano, J. Mich ...
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Giles, Graham G.
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Hakansson, Nicla ...
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Huang, Wen-Yi
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Lee, I-Min
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Linet, Martha S.
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MacInnis, Robert ...
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Park, Yikyung
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Prizment, Anna
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Purdue, Mark P.
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Riboli, Elio
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Robien, Kim
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Sandler, Dale P.
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Schairer, Cather ...
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Sesso, Howard D.
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Shu, Xiao Ou
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White, Emily
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Wolk, Alicja
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Xiang, Yong-Bing
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Zelenuich-Jacquo ...
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Zheng, Wei
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Patel, Alpa V.
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Hartge, Patricia
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de Gonzalez, Amy ...
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Gapstur, Susan M ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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