Atrial fibrillation is associated with different levels of physical activity levels at different ages in men

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Drca, NikolaKarolinska Institutet (författare)

Atrial fibrillation is associated with different levels of physical activity levels at different ages in men

Artikel/kapitelEngelska2014

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2014-05-14
BMJ PUBLISHING GROUP,2014
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LIBRIS-ID:oai:DiVA.org:uu-421981
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-421981URI
https://doi.org/10.1136/heartjnl-2013-305304DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:129135164URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

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Objective This study examines the influence of physical activity at different ages and of different types, on the risk of developing atrial fibrillation (AF) in a large cohort of Swedish men. Methods Information about physical activity was obtained from 44 410 AF-free men, aged 45-79 years (mean age=60), who had completed a self-administered questionnaire at baseline in 1997. Participants reported retrospectively their time spent on leisure-time exercise and on walking or bicycling throughout their lifetime (at 15, 30 and 50 years of age, and at baseline (mean age=60)). Participants were followed-up in the Swedish National Inpatient Register for ascertainment of AF. Cox proportional hazards regression models were used to estimate relative risks (RR) with 95% CIs, adjusted for potential confounders. Results During a median follow-up of 12 years, 4568 cases of AF were diagnosed. We observed a RR of 1.19 (95% CI 1.05 to 1.36) of developing AF in men who at the age of 30 years had exercised for >5 h/week compared with <1 h/week. The risk was even higher (RR 1.49, 95% CI 1.14 to 1.95) among the men who exercised >5 h/week at age 30 and quit exercising later in life (<1 h/week at baseline). Walking/bicycling at baseline was inversely associated with risk of AF (RR 0.87, 95% CI 0.77 to 0.97 for >1 h/day vs almost never) and the association was similar after excluding men with previous coronary heart disease or heart failure at baseline (corresponding RR 0.88, 95% CI 0.77 to 0.998). Conclusions Leisure-time exercise at younger age is associated with an increased risk of AF, whereas walking/bicycling at older age is associated with a decreased risk.

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Wolk, AlicjaKarolinska Institutet (författare)
Jensen-Urstad, MatsKarolinska Institutet (författare)
Larsson, Susanna C.Karolinska Institutet (författare)
Karolinska Institutet (creator_code:org_t)

Sammanhörande titlar

Ingår i:Heart: BMJ PUBLISHING GROUP100:13, s. 1037-10421355-60371468-201X

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Av författaren/redakt...: Drca, Nikola; Wolk, Alicja; Jensen-Urstad, M ...; Larsson, Susanna ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Kardiologi

Artiklar i publikationen: Heart

Av lärosätet: Uppsala universitet; Karolinska Institutet

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