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Intakes of Fruit, V...
Intakes of Fruit, Vegetables, and Carotenoids and Renal Cell Cancer Risk : A Pooled Analysis of 13 Prospective Studies
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- Lee, Jung Eun (författare)
- Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA.
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- Mannisto, Satu (författare)
- Natl Inst Hlth & Welf, Helsinki, Finland.
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- Spiegelman, Donna (författare)
- Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02115 USA.
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- Hunter, David J. (författare)
- Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
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- Bernstein, Leslie (författare)
- City Hope Natl Med Ctr, City Hope Comprehens Canc Ctr, Duarte, CA 91010 USA.;City Hope Natl Med Ctr, Beckman Res Inst, Duarte, CA 91010 USA.
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- van den Brandt, Piet A. (författare)
- Univ Maastricht, GROW Sch Oncol & Dev Biol, Dept Epidemiol, Maastricht, Netherlands.
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- Buring, Julie E. (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.
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- Cho, Eunyoung (författare)
- Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
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- English, Dallas R. (författare)
- Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.
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- Flood, Andrew (författare)
- Univ Minnesota, Sch Publ Hlth, Div Epidemiol & Community Hlth, Minneapolis, MN USA.
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- Freudenheim, Jo L. (författare)
- SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY 14260 USA.
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- Giles, Graham G. (författare)
- Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.
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- Giovannucci, Edward (författare)
- Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
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- Hakansson, Niclas (författare)
- Karolinska Institutet
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- Horn-Ross, Pamela L. (författare)
- No Calif Canc Ctr, Fremont, CA USA.
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- Jacobs, Eric J. (författare)
- Amer Canc Soc, Atlanta, GA 30329 USA.
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- Leitzmann, Michael F. (författare)
- Univ Regensburg, Inst Epidemiol & Prevent Med, Regensburg, Germany.
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- Marshall, James R. (författare)
- Roswell Pk Canc Inst, Buffalo, NY 14263 USA.
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- McCullough, Marjorie L. (författare)
- Amer Canc Soc, Atlanta, GA 30329 USA.
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- Miller, Anthony B. (författare)
- Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada.
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- Rohan, Thomas E. (författare)
- Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA.
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- Ross, Julie A. (författare)
- Univ Minnesota, Dept Pediat, Div Epidemiol & Clin Res, Minneapolis, MN 55455 USA.
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- Schatzkin, Arthur (författare)
- NCI, Div Canc Epidemiol & Genet, NIH, Dept Hlth & Hlth Serv, Bethesda, MD USA.
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- Schouten, Leo J. (författare)
- Univ Maastricht, GROW Sch Oncol & Dev Biol, Dept Epidemiol, Maastricht, Netherlands.
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- Virtamo, Jarmo (författare)
- Natl Inst Hlth & Welf, Helsinki, Finland.
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- Wolk, Alicja (författare)
- Karolinska Institutet
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- Zhang, Shumin M. (författare)
- Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Boston, MA USA.
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- Smith-Warner, Stephanie A. (författare)
- Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.
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Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA Natl Inst Hlth & Welf, Helsinki, Finland. (creator_code:org_t)
- AMER ASSOC CANCER RESEARCH, 2009
- 2009
- Engelska.
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Ingår i: Cancer Epidemiology, Biomarkers and Prevention. - : AMER ASSOC CANCER RESEARCH. - 1055-9965 .- 1538-7755. ; 18:6, s. 1730-1739
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Fruit and vegetable consumption has been hypothesized to reduce the risk of renal cell cancer. We conducted a pooled analysis of 13 prospective studies, including 1,478 incident cases of renal cell cancer (709 women and 769 men) among 530,469 women and 244,483 men followed for up to 7 to 20 years. Participants completed a validated food-frequency questionnaire at baseline. Using the primary data from each study, the study-specific relative risks (RR) were calculated using the Cox proportional hazards model and then pooled using a random effects model. We found that fruit and vegetable consumption was associated with a reduced risk of renal cell cancer. Compared with <200 g/d of fruit and vegetable intake, the pooled multivariate RR for >= 600 g/d was 0.68 [95% confidence interval (95% CI) = 0.54-0.87; P for between-studies heterogeneity = 0.86; P for trend = 0.001]. Compared with <100 g/d, the pooled multivariate RRs (95% CI) for 400 g/d were 0.79 (0.63-0.99; P for trend = 0.03) for total fruit and 0.72 (0.48-1.08; P for trend = 0.07) for total vegetables. For specific carotenoids, the pooled multivariate RRs (95% CIs) comparing the highest and lowest quintiles were 0.87 (0.73-1.03) for alpha-carotene, 0.82 (0.69-0.98) for beta-carotene, 0.86 (0.73-1.01) for beta-cryptoxanthin, 0.82 (0.64-1.06) for lutein/zeaxanthin, and 1.13 (0.95-1.34) for lycopene. In conclusion, increasing fruit and vegetable consumption is associated with decreasing risk of renal cell cancer; carotenoids present in fruit and vegetables may partly contribute to this protection. (Cancer Epidemiol Biomarkers Prev 2009;18(6):1730-9)
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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Lee, Jung Eun
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Mannisto, Satu
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Spiegelman, Donn ...
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Hunter, David J.
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Bernstein, Lesli ...
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van den Brandt, ...
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visa fler...
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Buring, Julie E.
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Cho, Eunyoung
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English, Dallas ...
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Flood, Andrew
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Freudenheim, Jo ...
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Giles, Graham G.
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Giovannucci, Edw ...
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Hakansson, Nicla ...
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Horn-Ross, Pamel ...
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Jacobs, Eric J.
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Leitzmann, Micha ...
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Marshall, James ...
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McCullough, Marj ...
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Miller, Anthony ...
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Rohan, Thomas E.
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Ross, Julie A.
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Schatzkin, Arthu ...
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Schouten, Leo J.
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Virtamo, Jarmo
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Wolk, Alicja
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Zhang, Shumin M.
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Smith-Warner, St ...
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- MEDICIN OCH HÄLSOVETENSKAP
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Cancer Epidemiol ...
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Uppsala universitet
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Karolinska Institutet