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Height, body mass i...
Height, body mass index, and ovarian cancer : A pooled analysis of 12 cohort studies
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- Schouten, Leo J. (författare)
- Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands.
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- Rivera, Christine (författare)
- Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.
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- Hunter, David J. (författare)
- Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA.
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- Spiegelman, Donna (författare)
- Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Biostat, Cambridge, MA 02138 USA.
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- Adami, Hans-Olov (författare)
- Karolinska Institutet
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- Arslan, Alan (författare)
- Karolinska Institutet
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- Beeson, W. Lawrence (författare)
- Loma Linda Univ, Sch Med, Ctr Hlth Res, Loma Linda, CA USA.
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- van den Brandt, Piet A. (författare)
- Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands.
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- Buring, Julie E. (författare)
- Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA.
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- Folsom, Aaron R. (författare)
- Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
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- Fraser, Gary E. (författare)
- Loma Linda Univ, Sch Med, Ctr Hlth Res, Loma Linda, CA USA.
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- Freudenheim, Jo L. (författare)
- SUNY Buffalo, Dept Social & Prevent Med, Buffalo, NY 14260 USA.
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- Goldbohm, R. Alexandra (författare)
- Netherlands Org Appl Sci Res Qual Life, Dept Food & Chem Risk Anal, Zeist, Netherlands.
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- Hankinson, Susan E. (författare)
- Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Lab, Boston, MA 02115 USA.;Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Med, Boston, MA 02115 USA.
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- Lacey, James V., Jr. (författare)
- NCI, NIH, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
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- Leitzmann, Michael (författare)
- NCI, NIH, Dept Hlth & Human Serv, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA.
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Lukanova, Annekatrin (författare)
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Marshall, James R. (författare)
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- Miller, Anthony B. (författare)
- Univ Toronto, Fac Med, Dept Publ Hlth Sci, Toronto, ON, Canada.
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- Patel, Alpa V. (författare)
- Amer Canc Soc, Atlanta, GA 30329 USA.
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- Rodriguez, Carmen (författare)
- Amer Canc Soc, Atlanta, GA 30329 USA.
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- Rohan, Thomas E. (författare)
- Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA.
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- Ross, Julie A. (författare)
- Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA.
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- Wolk, Alicja (författare)
- Karolinska Inst, Dept Environm Med, Div Nutr Epidemiol, Stockholm, Sweden.
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- Zhang, Shumin M. (författare)
- Harvard Univ, Brigham & Womens Hosp, Sch Med, Div Prevent Med, Boston, MA 02115 USA.
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- Smith-Warner, Stephanie A. (författare)
- Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA 02138 USA.
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Maastricht Univ, Dept Epidemiol, GROW Sch Oncol & Dev Biol, NL-6200 MD Maastricht, Netherlands Harvard Univ, Sch Publ Hlth, Dept Nutr, Cambridge, MA 02138 USA. (creator_code:org_t)
- AMER ASSOC CANCER RESEARCH, 2008
- 2008
- Engelska.
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Ingår i: Cancer Epidemiology, Biomarkers and Prevention. - : AMER ASSOC CANCER RESEARCH. - 1055-9965 .- 1538-7755. ; 17:4, s. 902-912
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background: Although many studies have investigated the association between anthropometry and ovarian cancer risk, results have been inconsistent. Methods: The associations of height, body mass index (BMI), and ovarian cancer risk were examined in a pooled analysis of primary data from 12 prospective cohort studies from North America and Europe. The study population consisted of 531,583 women among whom 2,036 epithelial ovarian cancer cases were identified. To summarize associations, study-specific relative risks (RR) were estimated using the Cox proportional hazards model and then combined using a random-effects model. Results: Women with height >= 1.70 m had a pooled multivariate RR of 1.38 [95% confidence interval (95% CI), 1.16-1-65] compared with those with height <1.60 m. For the same comparison, multivariate RRs were 1.79 (95% CI, 1.07-3.00) for premenopausal and 1.25 (95% CI, 1.04-1.49) for postmenopausal ovarian cancer (P(interaction) = 0.14). The multivariate RR for women with a BMI >= 30 kg/m(2) was 1.03 (95% CI, 0.86-1.22) compared with women with a BMI from 18.5 to 23 kg/m(2). For the same comparison, multivariate RRs were 1.72 (95% CI, 1.02-2.89) for premenopausal and 1.07 (95% CI, 0.87-1.33) for postmenopausal women (P(interaction) = 0.07). There was no statistically significant heterogeneity between studies with respect to height or BMI. BMI in early adulthood was not associated with ovarian cancer risk. Conclusion: Height was associated with an increased ovarian cancer risk, especially in premenopausal women. BMI was not associated with ovarian cancer risk in postmenopausal women but was positively associated with risk in premenopausal women.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
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- Av författaren/redakt...
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Schouten, Leo J.
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Rivera, Christin ...
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Hunter, David J.
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Spiegelman, Donn ...
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Adami, Hans-Olov
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Arslan, Alan
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visa fler...
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Beeson, W. Lawre ...
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van den Brandt, ...
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Buring, Julie E.
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Folsom, Aaron R.
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Fraser, Gary E.
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Freudenheim, Jo ...
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Goldbohm, R. Ale ...
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Hankinson, Susan ...
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Lacey, James V., ...
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Leitzmann, Micha ...
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Lukanova, Anneka ...
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Marshall, James ...
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Miller, Anthony ...
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Patel, Alpa V.
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Rodriguez, Carme ...
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Rohan, Thomas E.
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Ross, Julie A.
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Wolk, Alicja
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Zhang, Shumin M.
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Smith-Warner, St ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Reproduktionsmed ...
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Cancer Epidemiol ...
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Uppsala universitet
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Karolinska Institutet