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  • Artzi-Medvedik, RadaBen Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Nursing, Beer Sheva, Israel.;Ben Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Phys Therapy, Beer Sheva, Israel. (author)

Impaired kidney function is associated with lower quality of life among community-dwelling older adults The screening for CKD among older people across Europe (SCOPE) study

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • 2020-10-02
  • BMC,2020
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:uu-423937
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-423937URI
  • https://doi.org/10.1186/s12877-020-01697-3DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:du-35202URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:144913087URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background Quality of life (QoL) refers to the physical, psychological, social and medical aspects of life that are influenced by health status and function. The purpose of this study was to measure the self-perceived health status among the elderly population across Europe in different stages of Chronic Kidney Disease (CKD). Methods Our series consisted of 2255 community-dwelling older adults enrolled in the Screening for Chronic Kidney Disease (CKD) among Older People across Europe (SCOPE) study. All patients underwent a comprehensive geriatric assessment (CGA), including included demographics, clinical and physical assessment, number of medications taken, family arrangement, Geriatric Depression Scale (GDS), Cumulative Illness Rating Scale, History of falls, Lower urinary tract symptoms, and Short Physical Performance Battery (SPPB). Estimated glomerular filtration rate (eGFR) was calculated by Berlin Initiative Study (BIS) equation. Quality of life was assessed by Euro Qol questionnaire (Euro-Qol 5D) and EQ-Visual Analogue Scale (EQ-VAS). The association between CKD (eGFR < 60, < 45 ml or < 30 ml/min/1.73m(2)) and low EQoL-VAS was investigated by multivariable logistic regression models. Results CKD was found to be significantly associated with low EQoL-VAS in crude analysis (OR = 1.47, 95%CI = 1.16-1.85 for eGFR< 60; OR = 1.38, 95%CI = 1.08-1.77 for eGFR< 45; OR = 1.57, 95%CI = 1.01-2.44). Such association was no longer significant only when adjusting for SPPB (OR = 1.20, 95%CI = 0.93-1.56 for eGFR< 60; OR = 0.87, 95%CI = 0.64-1.18 for eGFR< 45; OR = 0.84, 95%CI = 0.50-1.42), CIRS and polypharmacy (OR = 1.16, 95%CI = 0.90-1.50 for eGFR< 60; OR = 0.86, 95%CI = 0.64-1.16 for eGFR< 45; OR = 1.11, 95%CI = 0.69-1.80) or diabetes, hypertension and chronic obstructive pulmonary disease (OR = 1.28, 95%CI = 0.99-1.64 for eGFR< 60; OR = 1.16, 95%CI = 0.88-1.52 for eGFR< 45; OR = 1.47, 95%CI = 0.92-2.34). The association between CKD and low EQoL-VAS was confirmed in all remaining multivariable models. Conclusions CKD may significantly affect QoL in community-dwelling older adults. Physical performance, polypharmacy, diabetes, hypertension and COPD may affect such association, which suggests that the impact of CKD on QoL is likely multifactorial and partly mediated by co-occurrent conditions/risk factors.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Kob, RobertFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging, Krankenhaus Barmherzige Bruder, Koberger Str 60, D-90408 Nurnberg, Germany. (author)
  • Fabbietti, PaoloItalian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Fermo, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Cosenza, Italy.;IRCCS INRCA, Lab Geriatr Pharmacoepidemiol & Biostat, Via S Margherita 5, I-60124 Ancona, Italy. (author)
  • Lattanzio, FabriziaItalian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Fermo, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Cosenza, Italy. (author)
  • Corsonello, AndreaKarolinska Institutet (author)
  • Melzer, YehuditBen Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Phys Therapy, Beer Sheva, Israel.;Maccabi Hlth Org, Tel Aviv, Israel. (author)
  • Roller-Wirnsberger, ReginaMed Univ Graz, Dept Internal Med, Graz, Austria. (author)
  • Wirnsberger, GerhardMed Univ Graz, Div Nephrol, Dept Internal Med, Graz, Austria. (author)
  • Mattace-Raso, FrancescoErasmus MC, Univ Med Ctr Rotterdam, Geriatr Med Sect, Dept Internal Med, Rotterdam, Netherlands. (author)
  • Tap, LisanneErasmus MC, Univ Med Ctr Rotterdam, Geriatr Med Sect, Dept Internal Med, Rotterdam, Netherlands. (author)
  • Gil, PedroHosp Clin San Carlos, Dept Geriatr Med, Madrid, Spain. (author)
  • Martinez, Sara LainezHosp Clin San Carlos, Dept Geriatr Med, Madrid, Spain. (author)
  • Formiga, FrancescBellvitge Univ Hosp, IDIBELL, Dept Internal Med, Geriatr Unit, Barcelona, Spain. (author)
  • Moreno-Gonzalez, RafaelBellvitge Univ Hosp, IDIBELL, Dept Internal Med, Geriatr Unit, Barcelona, Spain. (author)
  • Kostka, TomaszMed Univ Lodz, Hlth Ageing Res Ctr, Dept Geriatr, Lodz, Poland. (author)
  • Guligowska, AgnieszkaMed Univ Lodz, Hlth Ageing Res Ctr, Dept Geriatr, Lodz, Poland. (author)
  • Ärnlöv, JohanKarolinska Institutet,Högskolan Dalarna,Uppsala universitet,Institutionen för medicinska vetenskaper,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Family Med, Huddinge, Sweden.,Medicinsk vetenskap,Uppsala University; Karolinska Institutet(Swepub:du)jan (author)
  • Carlsson, Axel CUppsala universitet,Institutionen för medicinska vetenskaper,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.;Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Family Med, Huddinge, Sweden.(Swepub:uu)axeca883 (author)
  • Freiberger, EllenFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging, Krankenhaus Barmherzige Bruder, Koberger Str 60, D-90408 Nurnberg, Germany. (author)
  • Melzer, ItshakBen Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Phys Therapy, Beer Sheva, Israel. (author)
  • Ben Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Nursing, Beer Sheva, Israel.;Ben Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Dept Phys Therapy, Beer Sheva, Israel.Friedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging, Krankenhaus Barmherzige Bruder, Koberger Str 60, D-90408 Nurnberg, Germany. (creator_code:org_t)

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  • In:BMC Geriatrics: BMC201471-2318

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