Sökning: WFRF:(Wistuba Ignacio I)
> (2020-2021) >
A Grading System fo...
A Grading System for Invasive Pulmonary Adenocarcinoma : A Proposal From the International Association for the Study of Lung Cancer Pathology Committee
-
- Moreira, Andre L. (författare)
- New York Univ Langone Hlth, Dept Pathol, 560 First Ave,TH 4-15B, New York, NY 10016 USA.
-
- Ocampo, Paolo S. S. (författare)
- New York Univ Langone Hlth, Dept Pathol, 560 First Ave,TH 4-15B, New York, NY 10016 USA.
-
- Xia, Yuhe (författare)
- New York Univ Langone Hlth, Dept Biostat, New York, NY 10016 USA.
-
visa fler...
-
- Zhong, Hua (författare)
- New York Univ Langone Hlth, Dept Biostat, New York, NY 10016 USA.
-
- Russell, Prudence A. (författare)
- St Vincents Hosp, Dept Pathol, Fitzroy, Vic, Australia.
-
- Minami, Yuko (författare)
- Ibarakihigashi Natl Hosp, Dept Pathol, Tokai, Ibaraki, Japan.
-
- Cooper, Wendy A. (författare)
- Royal Prince Alfred Hosp, Dept Pathol, Camperdown, NSW, Australia.
-
- Yoshida, Akihiko (författare)
- Natl Canc Ctr, Dept Diagnost Pathol, Tokyo, Japan.
-
- Bubendorf, Lukas (författare)
- Univ Basel, Univ Hosp Basel, Inst Med Genet & Pathol, Basel, Switzerland.
-
- Papotti, Mauro (författare)
- Univ Turin, Dept Oncol, Turin, Italy.
-
- Pelosi, Giuseppe (författare)
- Univ Milan, Dept Pathol, Milan, Italy.;IRCCS MultiMed, Milan, Italy.
-
- Lopez-Rios, Fernando (författare)
- HM Hosp, Pathol Lab Dianas Terapeut, Madrid, Spain.
-
- Kunitoki, Keiko (författare)
- Harvard TH Chan Sch Publ Hlth, Boston, MA USA.
-
- Ferrari-Light, Dana (författare)
- New York Univ Langone Hlth, Dept Surg, New York, NY 10016 USA.
-
- Sholl, Lynette M. (författare)
- Harvard Med Sch, Brigham & Womens Hosp, Dept Pathol, Boston, MA 02115 USA.
-
- Beasley, Mary Beth (författare)
- Mt Sinai Hlth Syst, Icahn Sch Med, Dept Pathol, New York, NY USA.
-
- Borczuk, Alain (författare)
- Weill Cornell Med, Dept Pathol, New York, NY USA.
-
- Botling, Johan (författare)
- Uppsala universitet,Klinisk och experimentell patologi,Johan Botling
-
- Brambilla, Elisabeth (författare)
- Univ Grenoble Alpes, Dept Anat Pathol & Cytol, Grenoble, France.
-
- Chen, Gang (författare)
- Fudan Univ, Zhongshan Hosp, Dept Pathol, Shanghai, Peoples R China.
-
- Chou, Teh-Ying (författare)
- Taipei Vet Gen Hosp, Dept Pathol, Taipei, Taiwan.
-
- Chung, Jin-Haeng (författare)
- Seoul Natl Univ, Dept Pathol, Bundang Hosp, Seoul, South Korea.
-
- Dacic, Sanja (författare)
- Univ Pittsburgh, Dept Pathol, Med Ctr, Pittsburgh, PA USA.
-
- Jain, Deepali (författare)
- All India Inst Med Sci, Dept Pathol, New Delhi, India.
-
- Hirsch, Fred R. (författare)
- Tisch Canc Inst, Ctr Thorac Oncol, New York, NY USA.
-
- Hwang, David (författare)
- Sunnybrook Hlth Sci Ctr, Dept Lab Med & Mol Diagnost, Toronto, ON, Canada.
-
- Lantuejoul, Sylvie (författare)
- Ctr Leon Berard Unicanc, Dept Pathol, Lyon, France.
-
- Lin, Dongmei (författare)
- Peking Univ, Dept Pathol, Canc Hosp & Inst, Beijing, Peoples R China.
-
- Longshore, John W. (författare)
- Atrium Hlth, Carolinas Pathol Grp, Charlotte, NC USA.
-
- Motoi, Noriko (författare)
- Natl Canc Ctr, Dept Diagnost Pathol, Tokyo, Japan.
-
- Noguchi, Masayuki (författare)
- Univ Tsukuba, Dept Pathol, Tsukuba, Ibaraki, Japan.
-
- Poleri, Claudia (författare)
- Off Pathol Consultants, Buenos Aires, DF, Argentina.
-
- Rekhtman, Natasha (författare)
- Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA.
-
- Tsao, Ming-Sound (författare)
- Univ Hlth Network, Princess Margaret Canc Ctr, Toronto, ON, Canada.
-
- Thunnissen, Erik (författare)
- Vrije Univ Amsterdam Med Ctr, Dept Pathol, Amsterdam, Netherlands.
-
- Travis, William D. (författare)
- Mem Sloan Kettering Canc Ctr, Dept Pathol, 1275 York Ave, New York, NY 10021 USA.
-
- Yatabe, Yasushi (författare)
- Natl Canc Ctr, Dept Diagnost Pathol, Tokyo, Japan.
-
- Roden, Anja C. (författare)
- Mayo Clin, Dept Lab Med & Pathol, Rochester, MN USA.
-
- Daigneault, Jillian B. (författare)
- Int Assoc Study Lung Canc, Aurora, CO USA.
-
- Wistuba, Ignacio I. (författare)
- Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA.
-
- Kerr, Keith M. (författare)
- Aberdeen Royal Infirm, Dept Pathol, Aberdeen, Scotland.
-
- Pass, Harvey (författare)
- New York Univ Langone Hlth, Dept Surg, New York, NY 10016 USA.
-
- Nicholson, Andrew G. (författare)
- Royal Brompton & Harefield NHS Fdn Trust, Dept Pathol, London, England.;Imperial Coll, Natl Heart & Lung Inst, London, England.
-
- Mino-Kenudson, Mari (författare)
- Harvard Med Sch, Dept Pathol, Massachusetts Gen Hosp, Boston, MA 02115 USA.
-
visa färre...
-
New York Univ Langone Hlth, Dept Pathol, 560 First Ave,TH 4-15B, New York, NY 10016 USA New York Univ Langone Hlth, Dept Biostat, New York, NY 10016 USA. (creator_code:org_t)
- ELSEVIER SCIENCE INC, 2020
- 2020
- Engelska.
-
Ingår i: Journal of Thoracic Oncology. - : ELSEVIER SCIENCE INC. - 1556-0864 .- 1556-1380. ; 15:10, s. 1599-1610
- Relaterad länk:
-
http://www.jto.org/a...
-
visa fler...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- Introduction: A grading system for pulmonary adenocarcinoma has not been established. The International Association for the Study of Lung Cancer pathology panel evaluated a set of histologic criteria associated with prognosis aimed at establishing a grading system for invasive pulmonary adenocarcinoma. Methods: A multi-institutional study involving multiple cohorts of invasive pulmonary adenocarcinomas was conducted. A cohort of 284 stage I pulmonary adenocarcinomas was used as a training set to identify histologic features associated with patient outcomes (recurrence-free survival [RFS] and overall survival [OS]). Receiver operating characteristic curve analysis was used to select the best model, which was validated (n = 212) and tested (n = 300, including stage I-III) in independent cohorts. Reproducibility of the model was assessed using kappa statistics. Results: The best model (area under the receiver operating characteristic curve [AUC] = 0.749 for RFS and 0.787 for OS) was composed of a combination of predominant plus high-grade histologic pattern with a cutoff of 20% for the latter. The model consists of the following: grade 1, lepidic predominant tumor; grade 2, acinar or papillary predominant tumor, both with no or less than 20% of high-grade patterns; and grade 3, any tumor with 20% or more of high-grade patterns (solid, micropapillary, or complex gland). Similar results were seen in the validation (AUC = 0.732 for RFS and 0.787 for OS) and test cohorts (AUC = 0.690 for RFS and 0.743 for OS), confirming the predictive value of the model. Interobserver reproducibility revealed good agreement (k = 0.617). Conclusions: A grading system based on the predominant and high-grade patterns is practical and prognostic for invasive pulmonary adenocarcinoma. (C) 2020 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Nyckelord
- Adenocarcinoma
- Tumor grading
- Lung
- Model
- Prognosis
- Patologi
- Pathology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Moreira, Andre L ...
-
Ocampo, Paolo S. ...
-
Xia, Yuhe
-
Zhong, Hua
-
Russell, Prudenc ...
-
Minami, Yuko
-
visa fler...
-
Cooper, Wendy A.
-
Yoshida, Akihiko
-
Bubendorf, Lukas
-
Papotti, Mauro
-
Pelosi, Giuseppe
-
Lopez-Rios, Fern ...
-
Kunitoki, Keiko
-
Ferrari-Light, D ...
-
Sholl, Lynette M ...
-
Beasley, Mary Be ...
-
Borczuk, Alain
-
Botling, Johan
-
Brambilla, Elisa ...
-
Chen, Gang
-
Chou, Teh-Ying
-
Chung, Jin-Haeng
-
Dacic, Sanja
-
Jain, Deepali
-
Hirsch, Fred R.
-
Hwang, David
-
Lantuejoul, Sylv ...
-
Lin, Dongmei
-
Longshore, John ...
-
Motoi, Noriko
-
Noguchi, Masayuk ...
-
Poleri, Claudia
-
Rekhtman, Natash ...
-
Tsao, Ming-Sound
-
Thunnissen, Erik
-
Travis, William ...
-
Yatabe, Yasushi
-
Roden, Anja C.
-
Daigneault, Jill ...
-
Wistuba, Ignacio ...
-
Kerr, Keith M.
-
Pass, Harvey
-
Nicholson, Andre ...
-
Mino-Kenudson, M ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Cancer och onkol ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Klinisk laborato ...
- Artiklar i publikationen
-
Journal of Thora ...
- Av lärosätet
-
Uppsala universitet