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  • Guligowska, AgnieszkaMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (författare)

Association between kidney function, nutritional status and anthropometric measures in older people The Screening for CKD among Older People across Europe (SCOPE) study

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • 2020-10-02
  • BMC,2020
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:uu-424119
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-424119URI
  • https://doi.org/10.1186/s12877-020-01699-1DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:144878023URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:du-35200URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background Different mechanisms connect the nutritional status with the occurrence and the course of chronic kidney disease (CKD). The end-stage renal disease is complicated by catabolic inflammatory reactions and cachexia which leads to malnutrition (undernutrition). On the other hand, obesity is an important risk factor for the development and acceleration of CKD. Methods In the SCOPE study, community-dwelling persons aged 75 years and over, from 6 European countries and Israel were examined at the baseline phase. We assessed the relationship between anthropometric measures (Body Mass Index (BMI), circumferences of arm (AC), waist (WC), hip (HC), and calf (CC), waist-to-hip ratio - WHR, waist-to-height ratio - WHtR, risk of malnutrition (Mini Nutritional Assessment - MNA), serum albumin) and estimated glomerular filtration rate (eGFR) calculated by Berlin Initiative Study (BIS) equation. Results We studied 2151 subjects (932 men and 1219 women) with a mean age of 79.5 +/- 5.9 years. A total of 1333 (62%) participants had CKD (GRF < 60 ml/min/1.73 m(2)). Negative correlations between eGFR and weight, AC, WC, HC, CC, BMI, WHtR were observed. Positive correlation occurred between eGFR and MNA score (Spearman's rho = 0.11) and albumin concentration (rho = 0.09). Higher weight, AC, WC, HC, CC, BMI and WHtR increased the odds ratio of CKD; higher MNA (OR = 0.98, 95% CI 0.94-1.0) and higher serum albumin (OR = 0.73, 95% CI 0.53-1.0) were weakly associated with reduced odds. The risk of malnutrition was the highest with eGFR < 30 as compared to eGFR > 60 (OR = 2.95, 95%CI = 1.77-4.94 for MNA < 24; OR = 5.54, 95%CI = 1.66-18.5 for hypoalbuminemia < 3.5 g/dL). Conclusion The population of community dwelling people aged 75+ with CKD shows general features of overweight and obesity with a small prevalence of malnutrition. For anthropometric measures, the strongest association with eGFR and the highest odds of CKD were identified using WC, HC, CC and WHtR. Albumin level and MNA, but not MNA Short Form, indicated an increased odds of malnutrition with a decrease in eGFR.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Corsonello, AndreaKarolinska Institutet (författare)
  • Piglowska, MalgorzataMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (författare)
  • Roller-Wirnsberger, ReginaMed Univ Graz, Dept Internal Med, Graz, Austria. (författare)
  • Wirnsberger, GerhardMed Univ Graz, Dept Internal Med, Graz, Austria. (författare)
  • Ärnlöv, JohanHögskolan Dalarna,Karolinska Institutet,Uppsala universitet,Institutionen för folkhälso- och vårdvetenskap,Dalarna Univ, Sch Hlth & Social Studies, Falun, Sweden.;Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.,Medicinsk vetenskap,Uppsala University; Karolinska Institutet(Swepub:du)jan (författare)
  • Carlsson, Axel CUppsala universitet,Institutionen för folkhälso- och vårdvetenskap,Karolinska Inst, Div Family Med, Dept Neurobiol Care Sci & Soc, Huddinge, Sweden.(Swepub:uu)axeca883 (författare)
  • Tap, LisanneErasmus MC, Univ Med Ctr Rotterdam, Sect Geriatr Med, Dept Internal Med, Rotterdam, Netherlands. (författare)
  • Mattace-Raso, FrancescoErasmus MC, Univ Med Ctr Rotterdam, Sect Geriatr Med, Dept Internal Med, Rotterdam, Netherlands. (författare)
  • Formiga, FrancescBellvitge Univ Hosp, IDIBELL, Geriatr Unit, Dept Internal Med, Barcelona, Spain. (författare)
  • Moreno-Gonzalez, RafaelBellvitge Univ Hosp, IDIBELL, Geriatr Unit, Dept Internal Med, Barcelona, Spain. (författare)
  • Freiberger, EllenFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging, Krankenhaus Barmherzige Bruder, Koberger Str 60, D-90408 Nurnberg, Germany. (författare)
  • Sieber, CornelFriedrich Alexander Univ Erlangen Nurnberg, Dept Internal Med Geriatr, Inst Biomed Aging, Krankenhaus Barmherzige Bruder, Koberger Str 60, D-90408 Nurnberg, Germany. (författare)
  • Gregorio, Pedro GilHosp Clin San Carlos, Dept Geriatr, Madrid, Spain. (författare)
  • Martinez, Sara LainezHosp Clin San Carlos, Dept Geriatr, Madrid, Spain. (författare)
  • Artzi-Medvedik, RadaBen Gurion Univ Negev, Recanati Sch Community Hlth Profess, Fac Hlth Sci, Beer Sheva, Israel. (författare)
  • Yehoshua, IlanMaccabi Healthcare Serv Southern Reg, Tel Aviv, Israel. (författare)
  • Fabbietti, PaoloIRCCS INRCA, Lab Geriatr Pharmacoepidemiol & Biostat, Via S Margherita 5, I-60124 Ancona, Italy. (författare)
  • Lattanzio, FabriziaItalian Natl Res Ctr Aging IRCCS INRCA, Ancona, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Fermo, Italy.;Italian Natl Res Ctr Aging IRCCS INRCA, Cosenza, Italy. (författare)
  • Kostka, TomaszMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (författare)
  • Karolinska InstitutetMed Univ Lodz, Dept Geriatr, Hlth Ageing Res Ctr, Lodz, Poland. (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:BMC Geriatrics: BMC201471-2318

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