Sökning: WFRF:(Merino Jose L.) > Predictors of morta...
Fältnamn | Indikatorer | Metadata |
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000 | 15221naa a2201609 4500 | |
001 | oai:DiVA.org:uu-425114 | |
003 | SwePub | |
008 | 201116s2020 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4251142 URI |
024 | 7 | a https://doi.org/10.1111/ajt.157692 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Perez-Nadales, Elenau ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba IMIBIC, Cordoba, Spain.4 aut |
245 | 1 0 | a Predictors of mortality in solid organ transplant recipients with bloodstream infections due to carbapenemase-producing Enterobacterales :b The impact of cytomegalovirus disease and lymphopenia |
264 | 1 | b WILEY,c 2020 |
338 | a print2 rdacarrier | |
520 | a Treatment of carbapenemase-producing Enterobacterales bloodstream infections in solid organ transplant recipients is challenging. The objective of this study was to develop a specific score to predict mortality in solid organ transplant recipients with carbapenemase-producing Enterobacterales bloodstream infections. A multinational, retrospective (2004-2016) cohort study (INCREMENT-SOT, ClinicalTrials.gov NCT02852902) was performed. The main outcome variable was 30-day all-cause mortality. The INCREMENT-SOT-CPE score was developed using logistic regression. The global cohort included 216 patients. The final logistic regression model included the following variables: INCREMENT-CPE mortality score >= 8 (8 points), no source control (3 points), inappropriate empirical therapy (2 points), cytomegalovirus disease (7 points), lymphopenia (4 points), and the interaction between INCREMENT-CPE score >= 8 and CMV disease (minus 7 points). This score showed an area under the receiver operating characteristic curve of 0.82 (95% confidence interval [CI] 0.76-0.88) and classified patients into 3 strata: 0-7 (low mortality), 8-11 (high mortality), and 12-17 (very-high mortality). We performed a stratified analysis of the effect of monotherapy vs combination therapy among 165 patients who received appropriate therapy. Monotherapy was associated with higher mortality only in the very-high (adjusted hazard ratio [HR] 2.82, 95% CI 1.13-7.06, P = .03) and high (HR 9.93, 95% CI 2.08-47.40, P = .004) mortality risk strata. A score-based algorithm is provided for therapy guidance. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
653 | a antibiotic drug resistance | |
653 | a clinical research | |
653 | a practice | |
653 | a infection and infectious agents - bacterial | |
653 | a infectious disease | |
653 | a organ transplantation in general | |
700 | 1 | a Gutierrez-Gutierrez, Belenu ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Seville, Inst Biomed Sevilla, Hosp Univ Virgen Macarena,Dept Med, Unidad Clin Enfermedades Infecciosas Microbiol &, Seville, Spain.4 aut |
700 | 1 | a Natera, Alejandra M.u ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba IMIBIC, Cordoba, Spain.4 aut |
700 | 1 | a Abdala, Edsonu Univ Sao Paulo, Fac Med, Sao Paulo, Brazil.4 aut |
700 | 1 | a Magalhaes, Maira Reinau Univ Sao Paulo, Fac Med, Sao Paulo, Brazil.4 aut |
700 | 1 | a Mularoni, Alessandrau IRCCS ISMETT, Palermo, Italy.4 aut |
700 | 1 | a Monaco, Francescou IRCCS ISMETT, Palermo, Italy.4 aut |
700 | 1 | a Pierrotti, Ligia Camerau Univ Sao Paulo, Hosp Clin, Med Sch, Sao Paulo, Brazil.4 aut |
700 | 1 | a Freire, Maristela Pinheirou Univ Sao Paulo, Hosp Clin, Med Sch, Sao Paulo, Brazil.4 aut |
700 | 1 | a Iyer, Ranganathan N.u Global Hosp, Hyderabad, India.4 aut |
700 | 1 | a Steinke, Seema Mehtau Johns Hopkins Univ, Sch Med, Baltimore, MD USA.4 aut |
700 | 1 | a Calvi, Elisa Graziau ASST Papa Giovanni XXIII, Bergamo, Italy.4 aut |
700 | 1 | a Tumbarello, Mariou Fdn Policlin Univ Agostino Gemelli IRCCS, Rome, Italy.4 aut |
700 | 1 | a Falcone, Marcou Univ Pisa, Dept Clin & Expt Med, Pisa, Italy.4 aut |
700 | 1 | a Fernandez-Ruiz, Mariou Univ Complutense, Hosp Univ 12 Octubre, Inst Invest Hosp 12 Octubre Imas12, Unit Infect Dis, Madrid, Spain.4 aut |
700 | 1 | a Maria Costa-Mateo, Joseu Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba, Unidad Enfermedades Infecciosas, Cordoba, Spain.4 aut |
700 | 1 | a Rana, Meenakshi M.u Icahn Sch Med Mt Sinai, New York, NY 10029 USA.4 aut |
700 | 1 | a Varejao Strabelli, Tania Marau Univ Sch Med, Heart Inst Sao Paulo, Sao Paulo, Brazil.4 aut |
700 | 1 | a Paul, Micalu Rambam Hlth Care Campus, Infect Dis Inst, Haifa, Israel.;Technion Israel Fac Technol, Fac Med, Haifa, Israel.4 aut |
700 | 1 | a Carmen Farinas, Mariau Univ Cantabria, Hosp Univ Marques de Valdecilla, Infect Dis Unit, Santander, Spain.4 aut |
700 | 1 | a Clemente, Wanessa Trindadeu Univ Fed Minas Gerais, Fac Med, Liver Transplantat Program, Hosp Clin, Belo Horizonte, MG, Brazil.4 aut |
700 | 1 | a Roilides, Emmanuelu Aristotle Univ Thessaloniki, Hippokrat Hosp, Sch Hlth Sci, Infect Dis Unit, Thessaloniki, Greece.;Aristotle Univ Thessaloniki, Hippokrat Hosp, Sch Hlth Sci, Dept Pediat 3, Thessaloniki, Greece.4 aut |
700 | 1 | a Munoz, Patriciau Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain.;Univ Complutense Madrid, Fac Med, Inst Invest Sanitaria Gregorio Maranon, CIBER Enfermedades Resp CIBERES CB06 06 0058, Madrid, Spain.4 aut |
700 | 1 | a Dewispelaere, Laurentu Univ Libre Bruxelles, Dept Microbiol, CUB Hop Erasme, Brussels, Belgium.4 aut |
700 | 1 | a Loeches, Belenu Hosp La Paz, Infect Dis Unit, Madrid, Spain.4 aut |
700 | 1 | a Lowman, Warrenu Univ Witwatersrand, Fac Hlth Sci, Wits Donald Gordon Med Ctr, Vermaak & Partners Pathcare, Johannesburg, South Africa.4 aut |
700 | 1 | a Tan, Ban Hocku Singapore Gen Hosp, Dept Infect Dis, Singapore, Singapore.4 aut |
700 | 1 | a Escudero-Sanchez, Rosau ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Ramon y Cajal Univ Hosp, Madrid, Spain.4 aut |
700 | 1 | a Bodro, Martau Univ Barcelona, Hosp Clin IDIBAPS, Infect Dis Dept, Barcelona, Spain.4 aut |
700 | 1 | a Grossi, Paolo Antoniou Univ Insubria, Varese, Italy.4 aut |
700 | 1 | a Soldani, Fabiou Azienda Osped Univ Integrata Verona, Dept Med, Infect Dis Unit, Verona, Italy.4 aut |
700 | 1 | a Gunseren, Filizu Akdeniz Univ Hosp, Dept Infect Dis, Antalya, Turkey.4 aut |
700 | 1 | a Nestorova, Ninau Mater Dei Hosp, Msida, Malta.4 aut |
700 | 1 | a Pascual, Alvarou ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Seville, Inst Biomed Sevilla, Hosp Univ Virgen Macarena,Dept Med, Unidad Clin Enfermedades Infecciosas Microbiol &, Seville, Spain.4 aut |
700 | 1 | a Martinez-Martinez, Luisu ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Cordoba, Hosp Univ Reina Sofia, IMIBIC, Unidad Gest Clin Microbiol, Cordoba, Spain.4 aut |
700 | 1 | a Maria Aguado, Joseu ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Complutense, Hosp Univ 12 Octubre, Inst Invest Hosp 12 Octubre Imas12, Unit Infect Dis, Madrid, Spain.4 aut |
700 | 1 | a Rodriguez-Bano, Jesusu ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Seville, Inst Biomed Sevilla, Hosp Univ Virgen Macarena,Dept Med, Unidad Clin Enfermedades Infecciosas Microbiol &, Seville, Spain.4 aut |
700 | 1 | a Torre-Cisneros, Julianu ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba, Unidad Enfermedades Infecciosas, Cordoba, Spain.4 aut |
700 | 1 | a Song, A. T. Wanu Univ Sao Paulo, Fac Med, Sao Paulo, Brazil.4 aut |
700 | 1 | a Andraus, W.u Univ Sao Paulo, Fac Med, Sao Paulo, Brazil.4 aut |
700 | 1 | a Carneiro D'Albuquerque, L. A.u Univ Sao Paulo, Fac Med, Sao Paulo, Brazil.4 aut |
700 | 1 | a David-Neto, E.u Univ Sao Paulo, Hosp Clin, Med Sch, Dept Urol,Renal Transplantat Unit, Sao Paulo, Brazil.4 aut |
700 | 1 | a de Paula, F. Jotau Univ Sao Paulo, Hosp Clin, Med Sch, Dept Urol,Renal Transplantat Unit, Sao Paulo, Brazil.4 aut |
700 | 1 | a Rossi, F.u Univ Sao Paulo, Med Sch, Dept Microbiol, Div Cent Lab,Hosp Clin Complex, Sao Paulo, Brazil.4 aut |
700 | 1 | a Ostrander, D.u Johns Hopkins Univ, Sch Med, Div Infect Dis, Baltimore, MD 21218 USA.4 aut |
700 | 1 | a Avery, R.u Johns Hopkins Univ, Sch Med, Div Infect Dis, Baltimore, MD 21218 USA.4 aut |
700 | 1 | a Rizzi, M.u ASST Papa Giovanni XXIII, Infect Dis Unit, Bergamo, Italy.4 aut |
700 | 1 | a Losito, A. R.u Fdn Policlin Univ Agostino Gemelli IRCCS, Rome, Italy.4 aut |
700 | 1 | a Raffaelli, F.u Fdn Policlin Univ Agostino Gemelli IRCCS, Rome, Italy.4 aut |
700 | 1 | a Del Giacomo, P.u Fdn Policlin Univ Agostino Gemelli IRCCS, Rome, Italy.4 aut |
700 | 1 | a Tiseo, G.u Policlin Umberto 1, Rome, Italy.4 aut |
700 | 1 | a Lora-Tamayo, J.u Univ Complutense, Hosp Univ 12 Octubre, Inst Invest Hosp 12 Octubre, Unit Infect Dis, Madrid, Spain.4 aut |
700 | 1 | a San-Juan, R.u Univ Complutense, Hosp Univ 12 Octubre, Inst Invest Hosp 12 Octubre, Unit Infect Dis, Madrid, Spain.4 aut |
700 | 1 | a Gracia-Ahufinger, Iu Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba, Cordoba, Spain.4 aut |
700 | 1 | a Caston, J.u Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba, Cordoba, Spain.4 aut |
700 | 1 | a Ruiz, Y. A.u Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba, Cordoba, Spain.4 aut |
700 | 1 | a Altman, D. R.u Icahn Sch Med Mt Sinai, New York, NY 10029 USA.4 aut |
700 | 1 | a Campos, S. , V4 aut |
700 | 1 | a Bar-Sinai, N.u Technion Israel Fac Technol, Fac Med, Haifa, Israel.4 aut |
700 | 1 | a Koppel, F.u Rambam Hlth Care Campus, Infect Dis Inst, Haifa, Israel.4 aut |
700 | 1 | a de las Revillas Almajano, F. Arnaizu Marques de Valdecilla Univ Hosp, Infect Dis Unit, Santander, Spain.4 aut |
700 | 1 | a Gonzalez Rico, C.u Marques de Valdecilla Univ Hosp, Infect Dis Unit, Santander, Spain.4 aut |
700 | 1 | a Fernandez Martinez, M.u Marques de Valdecilla Univ Hosp, Microbiol Serv, Santander, Spain.4 aut |
700 | 1 | a Mourao, P. H. O.u Univ Fed Minas Gerais, Infect Control & Hosp Epidemiol, Hosp Clin, Belo Horizonte, MG, Brazil.4 aut |
700 | 1 | a Neves, F. A.u Univ Fed Minas Gerais, Infect Control & Hosp Epidemiol, Hosp Clin, Belo Horizonte, MG, Brazil.4 aut |
700 | 1 | a Ferreira, J.u Univ Fed Minas Gerais, Infect Control & Hosp Epidemiol, Hosp Clin, Belo Horizonte, MG, Brazil.4 aut |
700 | 1 | a Pyrpasopoulou, A.u Aristotle Univ Thessaloniki, Hippokrat Hosp, Sch Hlth Sci, Infect Dis Unit, Thessaloniki, Greece.4 aut |
700 | 1 | a Iosifidis, E.u Aristotle Univ Thessaloniki, Hippokrat Hosp, Sch Hlth Sci, Infect Dis Unit, Thessaloniki, Greece.4 aut |
700 | 1 | a Romiopoulos, Iu Aristotle Univ Thessaloniki, Hippokrat Hosp, Sch Hlth Sci, Infect Dis Unit, Thessaloniki, Greece.4 aut |
700 | 1 | a Minero, M. , V4 aut |
700 | 1 | a Sanchez-Carrillo, C.u Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain.;Inst Invest Sanitaria Gregorio Maranon, Madrid, Spain.4 aut |
700 | 1 | a Lardo, S.u IRCCS Roma, Ist Nazl Malattie Infett L Spallanzani, Rome, Italy.4 aut |
700 | 1 | a Coussement, J.u Univ Libre Bruxelles, Dept Microbiol, CUB Hop Erasme, Brussels, Belgium.4 aut |
700 | 1 | a Dodemont, M.u Univ Libre Bruxelles, Dept Microbiol, CUB Hop Erasme, Brussels, Belgium.4 aut |
700 | 1 | a Jiayun, K.u Singapore Gen Hosp, Dept Infect Dis, Singapore, Singapore.4 aut |
700 | 1 | a Martin-Davila, P.u Ramon y Cajal Univ Hosp, Madrid, Spain.4 aut |
700 | 1 | a Fortun, J.u Ramon y Cajal Univ Hosp, Madrid, Spain.4 aut |
700 | 1 | a Almela, M.u Univ Barcelona, Hosp Clin IDIBAPS, Barcelona, Spain.4 aut |
700 | 1 | a Moreno, A.u Univ Barcelona, Hosp Clin IDIBAPS, Barcelona, Spain.4 aut |
700 | 1 | a Linares, L.u Univ Barcelona, Hosp Clin IDIBAPS, Barcelona, Spain.4 aut |
700 | 1 | a Gasperina, D. D.u Univ Insubria, Varese, Italy.4 aut |
700 | 1 | a Balsamo, M. L.u Univ Insubria, Varese, Italy.4 aut |
700 | 1 | a Rovelli, C.u Univ Insubria, Varese, Italy.4 aut |
700 | 1 | a Concia, E.u Azienda Osped Univ Integrata Verona, Dept Med, Infect Dis Unit, Verona, Italy.4 aut |
700 | 1 | a Chiesi, S.u Azienda Osped Univ Integrata Verona, Dept Med, Infect Dis Unit, Verona, Italy.4 aut |
700 | 1 | a Salerno, D. N.u Azienda Osped Univ Integrata Verona, Dept Med, Infect Dis Unit, Verona, Italy.4 aut |
700 | 1 | a Ogunc, D.u Akdeniz Univ Hosp, Dept Clin Microbiol, Antalya, Turkey.4 aut |
700 | 1 | a Pilmis, B.u Univ Paris 05, Hop Necker Enfants Malad, Paris, France.4 aut |
700 | 1 | a Seminari, E. M.u Fdn IRCCS Policlin San Matteo, Pavia, Italy.4 aut |
700 | 1 | a Carratala, J.u Hosp Univ Bellvitge Barcelona, Barcelona, Spain.4 aut |
700 | 1 | a Dominguez, A.u Hosp Univ Bellvitge Barcelona, Barcelona, Spain.4 aut |
700 | 1 | a Cordero, E.u Hosp Univ Virgen del Rocio, Seville, Spain.4 aut |
700 | 1 | a Lepe, J. A.u Hosp Univ Virgen del Rocio, Seville, Spain.4 aut |
700 | 1 | a Montejo, M.u Hosp Univ Cruces, Bilbao, Spain.4 aut |
700 | 1 | a Merino de Lucas, E.u Hosp Gen Univ Alicante, Alicante, Spain.4 aut |
700 | 1 | a Eriksson, Britt-Marie,c Docent,d 1952-u Uppsala universitet,Infektionssjukdomar4 aut0 (Swepub:uu)breri424 |
700 | 1 | a van Delden, C.u Swiss Transplant Cohort Study, Zurich, Switzerland.4 aut |
700 | 1 | a Manuel, O.u Swiss Transplant Cohort Study, Zurich, Switzerland.4 aut |
700 | 1 | a Arslan, H.u Baskent Univ, Sch Med, Ankara, Turkey.4 aut |
700 | 1 | a Tufan, Z. Kocaku Yildirim Beyazit Univ, Ataturk T&R Hosp, Ankara, Turkey.4 aut |
700 | 1 | a Kazak, E.u Uludag Univ, Bursa, Turkey.4 aut |
700 | 1 | a David, M.u Univ Hosp Birmingham NHS Trust, Birmingham, W Midlands, England.4 aut |
700 | 1 | a Lease, E.u Univ Washington, Seattle, WA 98195 USA.4 aut |
700 | 1 | a Cornaglia, G.4 aut |
700 | 1 | a Akova, M.u Hacettepe Univ, Sch Med Sihhiye, Dept Infect Dis, Ankara, Turkey.4 aut |
710 | 2 | a ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Cordoba, Hosp Univ Reina Sofia, Inst Maimonides Invest Biomed Cordoba IMIBIC, Cordoba, Spain.b ISCIII, Spanish Network Res Infect Dis REIPI, Madrid, Spain.;Univ Seville, Inst Biomed Sevilla, Hosp Univ Virgen Macarena,Dept Med, Unidad Clin Enfermedades Infecciosas Microbiol &, Seville, Spain.4 org |
773 | 0 | t American Journal of Transplantationd : WILEYg 20:6, s. 1629-1641q 20:6<1629-1641x 1600-6135x 1600-6143 |
856 | 4 | u https://repositorio.unican.es/xmlui/bitstream/10902/18942/1/PredictorsMortalitySolid.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-425114 |
856 | 4 8 | u https://doi.org/10.1111/ajt.15769 |
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