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Common, intermediate and well-documented HLA alleles in world populations : CIWD version 3.0.0

Hurley, Carolyn K. (author)
Georgetown Univ, Dept Oncol, Washington, DC USA.
Kempenich, Jane (author)
Natl Marrow Donor Program, Minneapolis, MN USA.
Wadsworth, Kim (author)
Natl Marrow Donor Program, Minneapolis, MN USA.
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Sauter, Juergen (author)
DKMS, Tubingen, Germany.
Hofmann, Jan A. (author)
DKMS, Tubingen, Germany.
Schefzyk, Daniel (author)
DKMS, Tubingen, Germany.
Schmidt, Alexander H. (author)
DKMS, Tubingen, Germany.
Galarza, Pablo (author)
Argentine HSC Donors Registry, Buenos Aires, DF, Argentina.
Cardozo, Maria B. R. (author)
Argentine HSC Donors Registry, Buenos Aires, DF, Argentina.
Dudkiewicz, Malgorzata (author)
Cent Unrelated Potential Bone Marrow Donor & Cord, Warsaw, Poland.
Houdova, Lucie (author)
Univ West Bohemia, New Technol Informat Soc, Plzen, Czech Republic.
Jindra, Pavel (author)
Czech Natl Marrow Donors Registry, Plzen, Czech Republic.;Univ Hosp Plzen, Plzen, Czech Republic.
Sorensen, Betina S. (author)
Aarhus Univ Hosp, Danish Stem Cell Donors West, Aarhus, Denmark.
Jagannathan, Latha (author)
DKMS BMST Fdn India, Bangalore, Karnataka, India.;Bangalore Med Serv Trust, Bangalore, Karnataka, India.
Mathur, Ankit (author)
Bangalore Med Serv Trust, Bangalore, Karnataka, India.
Linjama, Tiina (author)
Finnish Stem Cell Registry, Helsinki, Finland.
Torosian, Tigran (author)
Fundacja DKMS, Warsaw, Poland.
Freudenberger, Rafi (author)
Gift Life Marrow Registry, Boca Raton, FL USA.
Manolis, Anastasios (author)
HTO, Athens, Greece.
Mavrommatis, John (author)
HTO, Athens, Greece.
Cereb, Nezih (author)
DATRI Blood Stem Cell Donor Registry, Chennai, Tamil Nadu, India.
Manor, Sigal (author)
Israel Ezer Mizion Bone Marrow Donor Registry, Bnei Braq, Israel.
Shriki, Nira (author)
Israel Ezer Mizion Bone Marrow Donor Registry, Bnei Braq, Israel.
Sacchi, Nicoletta (author)
Italian Bone Marrow Donor Registry, Genoa, Italy.
Ameen, Reem (author)
Kuwait Natl Stem Cell Registry, Jabriya, Kuwait.
Fisher, Raewyn (author)
New Zealand Bone Marrow Donor Registry, Auckland, New Zealand.
Dunckley, Heather (author)
New Zealand Blood Serv, Auckland, New Zealand.
Andersen, Irene (author)
Norwegian Bone Marrow Donor Registry, Oslo, Norway.
Alaskar, Ahmed (author)
King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr, Minist Natl Guard Hlth Affairs, Saudi Stem Cell Donor Registry, Riyadh, Saudi Arabia.
Alzahrani, Mohsen (author)
King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr, Minist Natl Guard Hlth Affairs, Saudi Stem Cell Donor Registry, Riyadh, Saudi Arabia.
Hajeer, Ali (author)
King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr, Minist Natl Guard Hlth Affairs, Saudi Stem Cell Donor Registry, Riyadh, Saudi Arabia.
Jawdat, Dunia (author)
King Saud bin Abdulaziz Univ Hlth Sci, King Abdullah Int Med Res Ctr, Minist Natl Guard Hlth Affairs, Saudi Stem Cell Donor Registry, Riyadh, Saudi Arabia.
Nicoloso, Grazia (author)
Swiss Blood Stem Cells, Bern, Switzerland.
Kupatawintu, Pawinee (author)
Thai Natl Stem Cell Donor Registry, Bangkok, Thailand.
Cho, Louise (author)
Bone Marrow Donor Programme, Singapore, Singapore.
Kaur, Ashminder (author)
Bone Marrow Donor Programme, Singapore, Singapore.
Bengtsson, Mats (author)
Uppsala universitet,Klinisk immunologi,Uppsala Univ, Tobias Registry Swedish Bone Marrow Donors, Uppsala, Sweden.
Dehn, Jason (author)
Natl Marrow Donor Program, Minneapolis, MN USA.
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Georgetown Univ, Dept Oncol, Washington, DC USA Natl Marrow Donor Program, Minneapolis, MN USA. (creator_code:org_t)
2020-01-31
2020
English.
In: HLA. - : WILEY. - 2059-2302 .- 2059-2310. ; 95:6, s. 516-531
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • A catalog of common, intermediate and well-documented (CIWD) HLA-A, -B, -C, -DRB1, -DRB3, -DRB4, -DRB5, -DQB1 and -DPB1 alleles has been compiled from over 8 million individuals using data from 20 unrelated hematopoietic stem cell volunteer donor registries. Individuals are divided into seven geographic/ancestral/ethnic groups and data are summarized for each group and for the total population. P (two-field) and G group assignments are divided into one of four frequency categories: common (>= 1 in 10 000), intermediate (>= 1 in 100 000), well-documented (>= 5 occurrences) or not-CIWD. Overall 26% of alleles in IPD-IMGT/HLA version 3.31.0 at P group resolution fall into the three CIWD categories. The two-field catalog includes 18% (n = 545) common, 17% (n = 513) intermediate, and 65% (n = 1997) well-documented alleles. Full-field allele frequency data are provided but are limited in value by the variations in resolution used by the registries. A recommended CIWD list is based on the most frequent category in the total or any of the seven geographic/ancestral/ethnic groups. Data are also provided so users can compile a catalog specific to the population groups that they serve. Comparisons are made to three previous CWD reports representing more limited population groups. This catalog, CIWD version 3.0.0, is a step closer to the collection of global HLA frequencies and to a clearer view of HLA diversity in the human population as a whole.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

Keyword

alleles
ethnic groups
gene frequency
HLA

Publication and Content Type

ref (subject category)
art (subject category)

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