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Rehabilitation Befo...
Rehabilitation Before and After Autologous Haematopoietic Stem Cell Transplantation (AHSCT) for Patients With Multiple Sclerosis (MS) : Consensus Guidelines and Recommendations for Best Clinical Practice on Behalf of the Autoimmune Diseases Working Party, Nurses Group, and Patient Advocacy Committee of the European Society for Blood and Marrow Transplantation (EBMT)
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- Roberts, Fiona (författare)
- Hobbs Rehabil, Winchester, Hants, England
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- Hobbs, Helen (författare)
- Hobbs Rehabil, Winchester, Hants, England
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- Jessop, Helen (författare)
- Sheffield Teaching Hosp NHS Fdn Trust, Sheffield, S Yorkshire, England
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- Bozzolini, Cristina (författare)
- Careggi Univ Hosp, Florence, Italy
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- Burman, Joachim, 1974- (författare)
- Uppsala universitet,Landtblom: Neurovetenskap
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- Greco, Raffaella (författare)
- San Raffaele Sci Hosp, Hematol & Bone Marrow Transplantat Unit, Ist Ricovero & Cura Carattere Sci IRCCS, Milan, Italy
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- Ismail, Azza (författare)
- Sheffield Teaching Hosp NHS Fdn Trust, Sheffield, S Yorkshire, England
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- Kazmi, Majid (författare)
- Guys Hosp, Dept Haematol, Kings Hlth Partners, London, England
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- Kirgizov, Kirill (författare)
- NN Blokhin Natl Med Res Ctr Oncol, Inst Paediat Oncol & Haematol, Moscow, Russia
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- Mancardi, Gianluigi (författare)
- Univ Genoa, Dept Neurosci, Genoa, Italy; Clin Sci Inst Maugeri, Genoa, Italy
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- Mawson, Susan (författare)
- Univ Sheffield, Sch Hlth & Related Res, Sheffield, S Yorkshire, England
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- Muraro, Paolo A. (författare)
- Imperial Coll London, Dept Brain Sci, London, England
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- Puyade, Mathieu (författare)
- CHU Poitiers, Serv Med Interne & Malad Infect, Poitiers, France; CHU Poitiers, CIC 1402, Poitiers, France
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- Saccardi, Riccardo (författare)
- Careggi Univ Hosp, Florence, Italy
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- Withers, Barbara (författare)
- Univ New South Wales Med, Dept Haematol & Blood Stem Cell Transplantat, St Vincents Hlth Network Sydney, Sydney, NSW, Australia; Univ New South Wales Med, St Vincents Clin Sch, Sydney, NSW, Australia
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- Verhoeven, Bregje (författare)
- Patient Advocacy Comm, EBMT Execut Off, Barcelona, Spain
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- Sharrack, Basil (författare)
- Sheffield Teaching Hosp NHS Fdn Trust, Sheffield, S Yorkshire, England; Univ Sheffield, Sch Hlth & Related Res, Sheffield, S Yorkshire, England
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- Snowden, John A. (författare)
- Sheffield Teaching Hosp NHS Fdn Trust, Sheffield, S Yorkshire, England
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(creator_code:org_t)
- 2020-12-11
- 2020
- Engelska.
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Ingår i: Frontiers in Neurology. - : Frontiers Media SA. - 1664-2295. ; 11
- Relaterad länk:
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https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
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https://www.frontier...
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Autologous haematopoietic stem cell transplantation (AHSCT) is increasingly used to treat people with multiple sclerosis (MS). Supported by an evolving evidence base, AHSCT can suppress active inflammation in the central nervous system and induce long-term changes in immune cell populations, thereby stabilizing, and, in some cases, reversing disability in carefully selected MS patients. However, AHSCT is an intensive chemotherapy-based procedure associated with intrinsic risks, including profound cytopenia, infection, and organ toxicity, accompanied by an on-going degree of immuno-compromise and general deconditioning, which can be associated with a transient increase in functional impairment in the early stages after transplantation. Although international guidelines and recommendations have been published for clinical and technical aspects of AHSCT in MS, there has been no detailed appraisal of the rehabilitation needed following treatment nor any specific guidelines as to how this is best delivered by hospital and community-based therapists and wider multidisciplinary teams in order to maximize functional recovery and quality of life. These expert consensus guidelines aim to address this unmet need by summarizing the evidence-base for AHSCT in MS and providing recommendations for current rehabilitation practice along with identifying areas for future research and development.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- autoimmune diseases
- autologous haematopoietic stem cell transplantation
- neurological diseases
- multiple sclerosis
- rehabilitation
- physical therapy
- exercise
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Roberts, Fiona
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Hobbs, Helen
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Jessop, Helen
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Bozzolini, Crist ...
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Burman, Joachim, ...
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Greco, Raffaella
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visa fler...
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Ismail, Azza
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Kazmi, Majid
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Kirgizov, Kirill
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Mancardi, Gianlu ...
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Mawson, Susan
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Muraro, Paolo A.
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Puyade, Mathieu
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Saccardi, Riccar ...
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Withers, Barbara
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Verhoeven, Bregj ...
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Sharrack, Basil
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Snowden, John A.
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