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Sökning: WFRF:(Maestre Gladys) > (2020-2024) > Association of Fata...

Association of Fatal and Nonfatal Cardiovascular Outcomes With 24-Hour Mean Arterial Pressure

Melgarejo, Jesus D. (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.;Univ Zulia, Fac Med, Lab Neurosci, Maracaibo, Venezuela.
Yang, Wen-Yi (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.;Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Sch Med, Dept Cardiol, Shanghai, Peoples R China.
Thijs, Lutgarde (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.
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Li, Yan (författare)
Shanghai Jiao Tong Univ, Ctr Epidemiol Studies & Clin Trials, Sch Med, Ruijin Hosp, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp,Sch Med, Shanghai, Peoples R China.
Asayama, Kei (författare)
Teikyo Univ, Dept Hyg & Publ Hlth, Sch Med, Tokyo, Japan.;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.
Hansen, Tine W. (författare)
Steno Diabet Ctr Copenhagen, Gentofte, Denmark.;Res Ctr Prevent & Hlth, Copenhagen, Capital Region, Denmark.
Wei, Fang-Fei (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.
Kikuya, Masahiro (författare)
Teikyo Univ, Dept Hyg & Publ Hlth, Sch Med, Tokyo, Japan.
Ohkubo, Takayoshi (författare)
Teikyo Univ, Dept Hyg & Publ Hlth, Sch Med, Tokyo, Japan.;Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.
Dolan, Eamon (författare)
Stroke & Hypertens Unit Blanchardstown, Dublin, Ireland.
Stolarz-Skrzypek, Katarzyna (författare)
Jagiellonian Univ, Med Coll, Dept Cardiol Intervent Electrocardiol & Hypertens, Krakow, Poland.
Huang, Qi-Fang (författare)
Shanghai Jiao Tong Univ, Ctr Epidemiol Studies & Clin Trials, Sch Med, Ruijin Hosp, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp,Sch Med, Shanghai, Peoples R China.
Tikhonoff, Valerie (författare)
Univ Padua, Dept Med, Padua, Italy.
Malyutina, Sofia (författare)
Russian Acad Sci, Siberian Branch, Inst Internal & Prevent Med Internal & Prevent Me, Inst Cytol & Genet, Novosibirsk, Russia.
Casiglia, Edoardo (författare)
Univ Padua, Dept Med, Padua, Italy.
Lind, Lars (författare)
Uppsala universitet,Geriatrik
Sandoya, Edgardo (författare)
Assoc Espanola Primera Socorros Mutuos, Montevideo, Uruguay.
Filipovsky, Jan (författare)
Charles Univ Prague, Fac Med, Plzen, Czech Republic.
Gilis-Malinowska, Natasza (författare)
Med Univ Gdansk, Dept Hypertens, Gdansk, Poland.
Narkiewicz, Krzysztof (författare)
Med Univ Gdansk, Dept Hypertens, Gdansk, Poland.
Kawecka-Jaszcz, Kalina (författare)
Jagiellonian Univ, Med Coll, Dept Cardiol Intervent Electrocardiol & Hypertens, Krakow, Poland.
Boggia, Jose (författare)
Univ Repdbl, Hosp Clin, Ctr Nefrol, Montevideo, Uruguay.;Univ Repdbl, Hosp Clin, Dept Fisiopatol, Montevideo, Uruguay.
Wang, Ji-Guang (författare)
Shanghai Jiao Tong Univ, Ctr Epidemiol Studies & Clin Trials, Sch Med, Ruijin Hosp, Shanghai, Peoples R China.;Shanghai Jiao Tong Univ, Ctr Vasc Evaluat, Shanghai Inst Hypertens, Shanghai Key Lab Hypertens,Ruijin Hosp,Sch Med, Shanghai, Peoples R China.
Imai, Yutaka (författare)
Tohoku Inst Management Blood Pressure, Sendai, Miyagi, Japan.
Vanassche, Thomas (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Ctr Mol & Vasc Biol, Leuven, Belgium.
Verhamme, Peter (författare)
Univ Leuven, KU Leuven, Dept Cardiovasc Sci, Ctr Mol & Vasc Biol, Leuven, Belgium.
Janssens, Stefan (författare)
Univ Hosp Leuven, Dept Internal Med, Div Cardiol, Leuven, Belgium.
O'Brien, Eoin (författare)
Univ Coll Dublin, Conway Inst, Dublin, Ireland.
Maestre, Gladys E. (författare)
Univ Zulia, Fac Med, Lab Neurosci, Maracaibo, Venezuela.;Univ Texas Rio Grande Valley, Sch Med, Dept Neurosci, Brownsville, TX USA.;Univ Texas Rio Grande Valley, Sch Med, Dept Human Genet, Brownsville, TX USA.;Univ Texas Rio Grande Valley, Alzheimers Dis Resource Ctr Minor Aging Res, Brownsville, TX USA.
Staessen, Jan A. (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.;Res Inst Alliance Promot Prevent Med, Mechelen, Belgium.
Zhang, Zhen-Yu (författare)
Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.
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Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium;Univ Zulia, Fac Med, Lab Neurosci, Maracaibo, Venezuela. Univ Leuven, KU Leuven, Res Unit Hypertens & Cardiovasc Epidemiol, Dept Cardiovasc Sci, Campus Sint Rafael,Kapucijnenvoer 7,Box 7001, BE-3000 Leuven, Belgium.;Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Sch Med, Dept Cardiol, Shanghai, Peoples R China. (creator_code:org_t)
Wolters Kluwer, 2021
2021
Engelska.
Ingår i: Hypertension. - : Wolters Kluwer. - 0194-911X .- 1524-4563. ; 77:1, s. 39-48
Relaterad länk:
https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Major adverse cardiovascular events are closely associated with 24-hour blood pressure (BP). We determined outcome-driven thresholds for 24-hour mean arterial pressure (MAP), a BP index estimated by oscillometric devices. We assessed the association of major adverse cardiovascular events with 24-hour MAP, systolic BP (SBP), and diastolic BP (DBP) in a population-based cohort (n=11 596). Statistics included multivariable Cox regression and the generalized R-2 statistic to test model fit. Baseline office and 24-hour MAP averaged 97.4 and 90.4 mm Hg. Over 13.6 years (median), 2034 major adverse cardiovascular events occurred. Twenty-four-hour MAP levels of <90 (normotension, n=6183), 90 to <92 (elevated MAP, n=909), 92 to <96 (stage-1 hypertension, n=1544), and >= 96 (stage-2 hypertension, n=2960) mm Hg yielded equivalent 10-year major adverse cardiovascular events risks as office MAP categorized using 2017 American thresholds for office SBP and DBP. Compared with 24-hour MAP normotension, hazard ratios were 0.96 (95% CI, 0.80-1.16), 1.32 (1.15-1.51), and 1.77 (1.59-1.97), for elevated and stage-1 and stage-2 hypertensive MAP. On top of 24-hour MAP, higher 24-hour SBP increased, whereas higher 24-hour DBP attenuated risk (P<0.001). Considering the 24-hour measurements, R-2 statistics were similar for SBP (1.34) and MAP (1.28), lower for DBP than for MAP (0.47), and reduced to null, if the base model included SBP and DBP; if the ambulatory BP indexes were dichotomized according to the 2017 American guideline and the proposed 92 mm Hg for MAP, the R-2 values were 0.71, 0.89, 0.32, and 0.10, respectively. In conclusion, the clinical application of 24-hour MAP thresholds in conjunction with SBP and DBP refines risk estimates.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

cardiovascular disease
hypertension
mean arterial pressure
mortality
oscillometry

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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