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3D diffractive imag...
3D diffractive imaging of nanoparticle ensembles using an x-ray laser
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- Ayyer, Kartik (författare)
- Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany.;Ctr Free Electron Laser Sci, D-22761 Hamburg, Germany.;Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.
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- Xavier, P. Lourdu (författare)
- Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany.;Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Bielecki, Johan (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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visa fler...
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- Shen, Zhou (författare)
- Natl Univ Singapore, Ctr Biolmaging Sci, Singapore 117557, Singapore.
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- Daurer, Benedikt J. (författare)
- Natl Univ Singapore, Ctr Biolmaging Sci, Singapore 117557, Singapore.
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- Samanta, Amit K. (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Awel, Salah (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Bean, Richard (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Barty, Anton (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Bergemann, Martin (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Ekeberg, Tomas, 1983- (författare)
- Uppsala universitet,Molekylär biofysik
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- Estillore, Armando D. (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Fangohr, Hans (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Giewekemeyer, Klaus (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Hunter, Mark S. (författare)
- SLAC Natl Accelerator Lab, Linac Coherent Light Source, Menlo Pk, CA 94025 USA.
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- Karnevskiy, Mikhail (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Kirian, Richard A. (författare)
- Arizona State Univ, Dept Phys, Tempe, AZ 85287 USA.
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- Kirkwood, Henry (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Kim, Yoonhee (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Koliyadu, Jayanath (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Lange, Holger (författare)
- Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany.
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- Letrun, Romain (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Lübke, Jannik (författare)
- Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Univ Hamburg, Dept Phys, D-22761 Hamburg, Germany.
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- Michelat, Thomas (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Morgan, Andrew J. (författare)
- Univ Melbourne, Phys, Melbourne, Vic, Australia.
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- Roth, Nils (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Univ Hamburg, Dept Phys, D-22761 Hamburg, Germany.
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- Sato, Tokushi (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Sikorski, Margin (författare)
- European XFEL, D-22869 Schenefeld, Germany.
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- Schulz, Florian (författare)
- Univ Hamburg, Inst Phys Chem, D-20146 Hamburg, Germany.
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- Spence, John C. H. (författare)
- Arizona State Univ, Dept Phys, Tempe, AZ 85287 USA.
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- Vagovic, Patrik (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;European XFEL, D-22869 Schenefeld, Germany.
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- Wollweber, Tamme (författare)
- Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany.;Ctr Free Electron Laser Sci, D-22761 Hamburg, Germany.;Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.
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- Worbs, Lena (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Univ Hamburg, Dept Phys, D-22761 Hamburg, Germany.
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- Yefanov, Oleksandr (författare)
- Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.
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- Zhuang, Yulong (författare)
- Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany.;Ctr Free Electron Laser Sci, D-22761 Hamburg, Germany.
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- Maia, Filipe R.N.C. (författare)
- Uppsala universitet,Molekylär biofysik,NERSC, Lawrence Berkeley Natl Lab, Berkeley, CA 94720 USA.
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- Horke, Daniel A. (författare)
- Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Radboud Univ Nijmegen, Inst Mol & Mat, NL-6525 AJ Nijmegen, Netherlands.
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- Küpper, Jochen (författare)
- Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Univ Hamburg, Dept Phys, D-22761 Hamburg, Germany.;Univ Hamburg, Dept Chem, D-20146 Hamburg, Germany.
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- Loh, N. Duane (författare)
- Natl Univ Singapore, Ctr Biolmaging Sci, Singapore 117557, Singapore.;Natl Univ Singapore, Dept Phys, Singapore 117551, Singapore.
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- Mancuso, Adrian P. (författare)
- European XFEL, D-22869 Schenefeld, Germany.;La Trobe Univ, La Trobe Inst Mol Sci, Dept Chem & Phys, Melbourne, Vic 3086, Australia.
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- Chapman, Henry N. (författare)
- Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany.;Univ Hamburg, Dept Phys, D-22761 Hamburg, Germany.
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Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany;Ctr Free Electron Laser Sci, D-22761 Hamburg, Germany.;Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany. Max Planck Inst Struct & Dynam Matter, D-22761 Hamburg, Germany.;Univ Hamburg, Hamburg Ctr Ultrafast Imaging, D-22761 Hamburg, Germany.;Ctr Free Electron LaserSci, DESY, D-22607 Hamburg, Germany. (creator_code:org_t)
- Optical Society of America, 2021
- 2021
- Engelska.
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Ingår i: Optica. - : Optical Society of America. - 2334-2536. ; 8:1, s. 15-23
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Single particle imaging at x-ray free electron lasers (XFELs) has the potential to determine the structure and dynamics of single biomolecules at room temperature. Two major hurdles have prevented this potential from being reached, namely, the collection of sufficient high-quality diffraction patterns and robust computational purification to overcome structural heterogeneity. We report the breaking of both of these barriers using gold nanoparticle test samples, recording around 10 million diffraction patterns at the European XFEL and structurally and orientationally sorting the patterns to obtain better than 3-nm-resolution 3D reconstructions for each of four samples. With these new developments, integrating advancements in x-ray sources, fast-framing detectors, efficient sample delivery, and data analysis algorithms, we illuminate the path towards sub-nano meter biomolecular imaging. The methods developed here can also be extended to characterize ensembles that are inherently diverse to obtain their full structural landscape. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License.
Ämnesord
- NATURVETENSKAP -- Fysik -- Den kondenserade materiens fysik (hsv//swe)
- NATURAL SCIENCES -- Physical Sciences -- Condensed Matter Physics (hsv//eng)
- NATURVETENSKAP -- Kemi -- Materialkemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Materials Chemistry (hsv//eng)
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Optica
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Ayyer, Kartik
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Xavier, P. Lourd ...
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Bielecki, Johan
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Shen, Zhou
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Daurer, Benedikt ...
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Samanta, Amit K.
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visa fler...
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Awel, Salah
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Bean, Richard
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Barty, Anton
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Bergemann, Marti ...
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Ekeberg, Tomas, ...
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Estillore, Arman ...
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Fangohr, Hans
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Giewekemeyer, Kl ...
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Hunter, Mark S.
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Karnevskiy, Mikh ...
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Kirian, Richard ...
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Kirkwood, Henry
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Kim, Yoonhee
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Koliyadu, Jayana ...
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Lange, Holger
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Letrun, Romain
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Lübke, Jannik
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Michelat, Thomas
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Morgan, Andrew J ...
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Roth, Nils
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Sato, Tokushi
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Sikorski, Margin
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Schulz, Florian
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Spence, John C. ...
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Vagovic, Patrik
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Wollweber, Tamme
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Worbs, Lena
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Yefanov, Oleksan ...
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Zhuang, Yulong
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Maia, Filipe R.N ...
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Horke, Daniel A.
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Küpper, Jochen
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Loh, N. Duane
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Mancuso, Adrian ...
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Chapman, Henry N ...
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- NATURVETENSKAP
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NATURVETENSKAP
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NATURVETENSKAP
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Optica
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Uppsala universitet