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  • Zhang, WeiGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)

Surgical treatment of low-grade brain tumors associated with epilepsy

  • Article/chapterEnglish2020

Publisher, publication year, extent ...

  • LONDON ENGLAND :Elsevier,2020
  • printrdacarrier

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  • LIBRIS-ID:oai:DiVA.org:uu-436120
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-436120URI
  • https://doi.org/10.1016/bs.irn.2020.03.021DOI

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  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:kap swepub-publicationtype

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  • Objective: To explore the strategy of surgical treatment of low-grade brain tumors associated with epilepsy. Methods: Clinical data of 158 patients with low-grade brain tumors were collected from January 2011 to December 2017 in Guangdong Sanjiu brain hospital. All patients received Preoperative evaluation. Lesion site: 18 cases were located in multiple cerebral lobes, 10 cases were in the functional zones, 130 cases were in the non-functional zones (including 74 cases were in the medial of temporal lobe). The surgical strategy included subtotal resection, gross-total resection and enlarged resection. Postoperative effects were evaluated by Engel classification. Results: A total of 158 patients underwent surgical treatment, among these patients, only 1 patient underwent intracranial electrode implantation. Surgical methods: 34 cases of subtotal resection, 3 cases of gross-total resection, 119 cases of enlarged resection (including Anterior temporal lobectomy in 74 cases) and 2 case of Selective hippocampal amygdalectomy. The final pathology suggested that there are 74 cases of ganglionglioma, 25 cases of dysembryoplastic neuroepithelial tumors, 9 cases of pilocytic astrocytoma, 16 cases of oligodendroglioma, 10 cases of pleomorphic xanthoastrocytoma, 4 case of diffuse astrocytoma, 9 cases of unclassified astrocytoma, 11 case of oligoastrocytoma. The follow-up time was between 1 and 7 years, with an average of 3.44 +/- 1.77 years. Postoperative recovery: 147 patients had an Engel Class I outcome, 10 patients were in Engel Class II, 1 patient was in Class IV. Conclusion: The strategy of surgical treatment of low-grade brain tumors associated with epilepsy should pay more attention to the preoperative assessment of the epileptogenic zone. The tumor is not exactly the same as the epileptogenic zone, and the strategy of surgical treatment depends on the tumor feature as well as whether it was located in temporal lobe or involved in functional areas.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Chen, JunxiGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Hua, GangGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Zhu, DanGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Tan, QinghuaGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Zhang, LimingGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Wang, GenboGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Ding, MeichaoGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Hu, XiangshuGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Li, HuaGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Sharma, Hari ShankerUppsala universitet,Anestesiologi och intensivvård,Institutionen för medicinsk cellbiologi(Swepub:uu)hssharma (author)
  • Guo, QiangGuangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China. (author)
  • Guangdong Sanjiu Brain Hosp, Epilepsy Ctr, Guangzhou, Peoples R China.Anestesiologi och intensivvård (creator_code:org_t)

Related titles

  • In:NOVEL THERAPEUTIC ADVANCES IN GLIOBLASTOMALONDON ENGLAND : Elsevier, s. 171-1839780128211144

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