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Community health st...
Community health status and outcomes after allogeneic hematopoietic cell transplantation in the United States
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- Hong, Sanghee (författare)
- Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.
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- Brazauskas, Ruta (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Med Coll Wisconsin, Inst Hlth & Equ, Div Biostat, Milwaukee, WI 53226 USA.
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- Hebert, Kyle M. (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.
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visa fler...
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- Ganguly, Siddhartha (författare)
- Univ Kansas Hlth Syst, Div Hematol Malignancy & Cellular Therapeut, Kansas City, KS USA.
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- Abdel-Azim, Hisham (författare)
- Univ Southern Calif, Childrens Hosp Los Angeles, Keck Sch Med, Div Hematol Oncol & Blood & Marrow Transplantat, Los Angeles, CA 90007 USA.
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- Diaz, Miguel Angel (författare)
- Univ Nino Jesus, Dept Hematol Oncol, Hosp Infantil, Madrid, Spain.
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- Beattie, Sara (författare)
- Tom Baker Canc Clin, Dept Psychosocial Oncol & Rehabil, Calgary, AB, Canada.;Univ Calgary, Dept Oncol, Calgary, AB, Canada.
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- Ciurea, Stefan O. (författare)
- Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA.
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- Szwajcer, David (författare)
- Univ Manitoba, Winnipeg, MB, Canada.,King Faisal Specialist Hosp & Res Ctr, Dept Oncol, Riyadh, Saudi Arabia.
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- Badawy, Sherif M. (författare)
- Ann & Robert H Lurie Childrens Hosp Chicago, Div Hematol Oncol & Stem Cell Transplant, Chicago, IL 60611 USA.;Northwestern Univ, Dept Pediat, Feinberg Sch Med, Chicago, IL 60611 USA.
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- Gratwohl, Alois A. (författare)
- Univ Hosp Basel, Basel, Switzerland.
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- LeMaistre, Charles (författare)
- Sarah Cannon, Hematol & Bone Marrow Transplant, Nashville, TN USA.
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- Aljurf, Mahmoud D. S. M. (författare)
- King Faisal Specialist Hosp & Res Ctr, Dept Oncol, Riyadh, Saudi Arabia.,Dokkyo Med Univ, Dept Hematol & Oncol, Mibu, Tochigi, Japan.
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- Olsson, Richard (författare)
- Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Dept Lab Med, Stockholm, Sweden.
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- Bhatt, Neel S. (författare)
- Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
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- Farhadfar, Nosha (författare)
- Univ Florida, Coll Med, Div Hematol Oncol, Gainesville, FL USA.
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- Yared, Jean A. (författare)
- Univ Maryland, Dept Med, Blood & Marrow Transplantat Program, Div Hematol Oncol,Greenebaum Comprehens Canc Ctr, Baltimore, MD 21201 USA.
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- Yoshimi, Ayami (författare)
- Univ Freiburg, Div Pediat Hematol & Oncol, Dept Pediat & Adolescent Med, Med Ctr, Freiburg, Germany.
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- Seo, Sachiko (författare)
- Dokkyo Med Univ, Dept Hematol & Oncol, Mibu, Tochigi, Japan.,Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.
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- Gergis, Usama (författare)
- Thomas Jefferson Univ, Philadelphia, PA 19107 USA.
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- Beitinjaneh, Amer M. (författare)
- Univ Miami, Miami, FL USA.
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- Sharma, Akshay (författare)
- St Jude Childrens Res Hosp, Dept Bone Marrow Transplantat & Cellular Therapy, 332 N Lauderdale St, Memphis, TN 38105 USA.
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- Lazarus, Hillard (författare)
- Case Western Reserve Univ, Univ Hosp Cleveland, Med Ctr, Cleveland, OH 44106 USA.
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- Law, Jason (författare)
- Tufts Med Ctr, Div Pediat Hematol Oncol, Floating Hosp Children, Boston, MA 02111 USA.
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- Ulrickson, Matthew (författare)
- Banner MD Anderson Canc Ctr, Gilbert, AZ USA.
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- Hashem, Hasan (författare)
- King Hussein Canc Ctr, Div Pediat Hematol Oncol & Bone Marrow Transplant, Amman, Jordan.
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- Schoemans, Helene (författare)
- Univ Hosp Leuven, Dept Hematol, Leuven, Belgium.;Katholieke Univ Leuven, Leuven, Belgium.
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- Cerny, Jan (författare)
- Univ Massachusetts, Med Ctr, Dept Med, Div Hematol Oncol, Worcester, MA USA.
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- Rizzieri, David (författare)
- Duke Univ, Div Hematol Malignancies & Cellular Therapy, Durham, NC USA.
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- Savani, Bipin N. (författare)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Hematol Oncol, Nashville, TN USA.
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- Kamble, Rammurti T. (författare)
- Baylor Coll Med, Div Hematol & Oncol, Ctr Cell & Gene Therapy, Houston, TX 77030 USA.
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- Shaw, Bronwen E. (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.
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- Khera, Nandita (författare)
- Mayo Clin, Dept Hematol Oncol, Phoenix, AZ USA.
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- Wood, William A. (författare)
- Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC 27515 USA.
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- Hashmi, Shahrukh (författare)
- Mayo Clin, Dept Internal Med, Rochester, MN USA.
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- Hahn, Theresa (författare)
- Roswell Park Comprehens Canc Ctr, Dept Med, Buffalo, NY USA.
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- Lee, Stephanie J. (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
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- Rizzo, J. Douglas (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.
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- Majhail, Navneet S. (författare)
- Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA.
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- Saber, Wael (författare)
- Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.
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Cleveland Clin, Taussig Canc Ctr, Blood & Marrow Transplant Program, 9500 Euclid Ave,CA60, Cleveland, OH 44195 USA Med Coll Wisconsin, Dept Med, Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Med Coll Wisconsin, Inst Hlth & Equ, Div Biostat, Milwaukee, WI 53226 USA. (creator_code:org_t)
- 2020-10-21
- 2021
- Engelska.
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Ingår i: Cancer. - : John Wiley & Sons. - 0008-543X .- 1097-0142. ; 127:4, s. 609-618
- Relaterad länk:
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: The association of community factors and outcomes after hematopoietic cell transplantation (HCT) has not been comprehensively described. Using the County Health Rankings and Roadmaps (CHRR) and the Center for International Blood and Marrow Transplant Research (CIBMTR), this study evaluated the impact of community health status on allogeneic HCT outcomes.Methods: This study included 18,544 adult allogeneic HCT recipients reported to the CIBMTR by 170 US centers in 2014-2016. Sociodemographic, environmental, and community indicators were derived from the CHRR, an aggregate community risk score was created, and scores were assigned to each patient (patient community risk score [PCS]) and transplant center (center community risk score [CCS]). Higher scores indicated less healthy communities. The impact of PCS and CCS on patient outcomes after allogeneic HCT was studied.Results: The median age was 55 years (range, 18-83 years). The median PCS was -0.21 (range, -1.37 to 2.10; standard deviation [SD], 0.42), and the median CCS was -0.13 (range, -1.04 to 0.96; SD, 0.40). In multivariable analyses, a higher PCS was associated with inferior survival (hazard ratio [HR] per 1 SD increase, 1.04; 99% CI, 1.00-1.08;P= .0089). Among hematologic malignancies, a tendency toward inferior survival was observed with a higher PCS (HR, 1.04; 99% CI, 1.00-1.08;P= .0102); a higher PCS was associated with higher nonrelapse mortality (NRM; HR, 1.08; 99% CI, 1.02-1.15;P= .0004). CCS was not significantly associated with survival, relapse, or NRM.Conclusions: Patients residing in counties with a worse community health status have inferior survival as a result of an increased risk of NRM after allogeneic HCT. There was no association between the community health status of the transplant center location and allogeneic HCT outcomes.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
Nyckelord
- allogeneic transplant
- community health
- hematopoietic cell transplantation
- survival
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Cancer
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- Av författaren/redakt...
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Hong, Sanghee
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Brazauskas, Ruta
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Hebert, Kyle M.
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Ganguly, Siddhar ...
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Abdel-Azim, Hish ...
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Diaz, Miguel Ang ...
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visa fler...
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Beattie, Sara
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Ciurea, Stefan O ...
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Szwajcer, David
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Badawy, Sherif M ...
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Gratwohl, Alois ...
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LeMaistre, Charl ...
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Aljurf, Mahmoud ...
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Olsson, Richard
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Bhatt, Neel S.
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Farhadfar, Nosha
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Yared, Jean A.
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Yoshimi, Ayami
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Seo, Sachiko
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Gergis, Usama
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Beitinjaneh, Ame ...
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Sharma, Akshay
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Lazarus, Hillard
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Law, Jason
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Ulrickson, Matth ...
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Hashem, Hasan
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Schoemans, Helen ...
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Cerny, Jan
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Rizzieri, David
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Savani, Bipin N.
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Kamble, Rammurti ...
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Shaw, Bronwen E.
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Khera, Nandita
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Wood, William A.
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Hashmi, Shahrukh
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Hahn, Theresa
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Lee, Stephanie J ...
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Rizzo, J. Dougla ...
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Majhail, Navneet ...
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Saber, Wael
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Cancer och onkol ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Hematologi
- Artiklar i publikationen
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Cancer
- Av lärosätet
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Uppsala universitet
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Karolinska Institutet