Sökning: WFRF:(Kennebäck Göran) >
Atrial fibrillation...
Atrial fibrillation burden, episode duration and frequency in relation to quality of life in patients with implantable cardiac monitor
-
- Jansson, Victoria (författare)
- Uppsala universitet,Kardiologi-arrytmi,Department of Medical Sciences, Uppsala University, Uppsala, Sweden
-
- Bergfeldt, Lennart, 1950 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine/Cardiology, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, and Region Västra Götaland, Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden
-
- Schwieler, Jonas (författare)
- Department of Cardiology, Karolinska University Hospital, Solna SE 171 76, Stockholm, Sweden
-
visa fler...
-
- Kennebäck, Göran (författare)
- Department of Cardiology, Karolinska University Hospital, Solna SE 171 76, Stockholm, Sweden
-
- Rubulis, Aigars, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Department of Molecular and Clinical Medicine/Cardiology, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, and Region Västra Götaland, Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden
-
- Jensen, Steen M. (författare)
- Umeå universitet,Avdelningen för medicin
-
- Raatikainen, Pekka (författare)
- Department of Cardiology, Heart and Lung Center, Helsinki University Hospital, Finland
-
- Sciaraffia, Elena, 1977- (författare)
- Uppsala universitet,Kardiologi-arrytmi,Department of Medical Sciences, Uppsala University, Uppsala, Sweden
-
- Blomström-Lundqvist, Carina (författare)
- Uppsala universitet,Kardiologi-arrytmi,Department of Medical Sciences, Uppsala University, Uppsala, Sweden
-
visa färre...
-
(creator_code:org_t)
- Elsevier BV, 2021
- 2021
- Engelska.
-
Ingår i: IJC Heart & Vasculature. - : Elsevier BV. - 2352-9067. ; 34
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://uu.diva-port... (primary) (Raw object)
-
https://doi.org/10.1...
-
https://umu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://gup.ub.gu.se...
-
https://urn.kb.se/re...
-
visa färre...
Abstract
Ämnesord
Stäng
- Aims: To assess the relation between atrial fibrillation (AF) characteristics and health-related quality of life (QoL), and which AF characteristic had the greatest impact.Method: The AF characteristics burden (percentage of time in AF), duration and number of AF episodes/month were obtained from implantable cardiac monitors during the 2-month run-in period in 150 patients included in the randomized CAPTAF trial comparing early ablation and antiarrhythmic drug therapy. The QoL was measured by the General Health and Vitality dimensions of the 36-Item Short-Form Health Survey. AF characteristics were analysed continuously and in quartiles (Q1-Q4).Results: Greater AF burden (p = 0.003) and longer AF episodes (p = 0.013) were associated with impaired QoL (Vitality score only) in simple linear regression analyses. Greater AF burden was, however, the only AF characteristic associated with lower QoL, when adjusted for sex, type of AF, hypertension, heart rate above 110 beats per minute during AF, and beta-blocker use in multiple linear regression analyses. For every 10% increase in AF burden there was a 1.34-point decrease of Vitality score (95% confidence interval (CI) -2.67 to -0.02, p = 0.047). The Vitality score was 12 points lower (95% CI -22.73 to -1.27, p = 0.03) in patients with an AF burden > 33% (Q4) versus those with < 0.45% (Q1), but only in unadjusted analysis.Conclusion: AF burden had a greater impact on QoL (Vitality), than the duration and number of AF episodes, corroborating that AF burden may be the preferred outcome measure of rhythm control in trials including relatively healthy AF populations.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- Atrial fibrillation
- Atrial fibrillation burden
- Health-related quality of life
- Implantable cardiac monitor
- Loop recorder
- Randomized
- Cardiology
- Kardiologi
- Atrial fibrillation
- Atrial fibrillation burden
- Health-related quality of life
- Implantable cardiac monitor
- Loop recorder
- Randomized
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas