The deep population history in Africa

Africa is the continent with the greatest genetic diversity among humans and the level of diversity is further enhanced by incorporating non-majority groups, which are often understudied. Many of today's minority populations historically practiced foraging lifestyles, which were the only subsistence strategies prior to the rise of agriculture and pastoralism, but only a few groups practicing these strategies remain today. Genomic investigations of Holocene human remains excavated across the African continent show that the genetic landscape was vastly different compared to today's genetic landscape and that many groups that today are population isolate inhabited larger regions in the past. It is becoming clear that there are periods of isolation among groups and geographic areas, but also genetic contact over large distances throughout human history in Africa. Genomic information from minority populations and from prehistoric remains provide an invaluable source of information on the human past, in particular deep human population history, as Holocene large-scale population movements obscure past patterns of population structure. Here we revisit questions on the nature and time of the radiation of early humans in Africa, the extent of gene-flow among human populations as well as introgression from archaic and extinct lineages on the continent.

Breton, GwennaUppsala universitet,Människans evolution(Swepub:uu)gwebr906 (author)
Sjödin, PerUppsala universitet,Människans evolution(Swepub:uu)pesjo150 (author)
Jakobsson, MattiasUppsala universitet,Science for Life Laboratory, SciLifeLab,Människans evolution,Univ Johannesburg, Palaeo Res Inst, Phys, Cnr Kingsway & Univ Rd, ZA-2092 Johannesburg, South Africa(Swepub:uu)matja323 (author)
Uppsala universitetMänniskans evolution (creator_code:org_t)

In:Human Molecular Genetics: Oxford University Press30:R1, s. R2-R100964-69061460-2083

By the author/editor: Hollfelder, Nina; Breton, Gwenna; Sjödin, Per; Jakobsson, Matti ...

About the subject

NATURAL SCIENCES: NATURAL SCIENCES; and Biological Scien ...; and Evolutionary Bio ...

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