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Impact of autologou...
Impact of autologous blood transfusion after bone marrow harvest on unrelated donor's health and outcome : a CIBMTR analysis
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- Farhadfar, Nosha (författare)
- Shands HealthCare, Dept Med, Div Hematol & Oncol, Gainesville, FL USA.;Univ Florida, Gainesville, FL USA.
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- Murthy, Hemant S. (författare)
- Mayo Clin, Div Hematol Oncol, Blood & Marrow Transplantat Program, Jacksonville, FL 32224 USA.
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- Logan, Brent R. (författare)
- Med Coll Wisconsin, Dept Med, CIBMTR Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.;Med Coll Wisconsin, Inst Hlth & Soc, Div Biostat, Milwaukee, WI 53226 USA.
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visa fler...
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- Sees, Jennifer A. (författare)
- CIBMTR Ctr Int Blood & Marrow Transplant Res, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.
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- Mouhab, Ayas (författare)
- King Faisal Specialist Hosp & Res Ctr, Riyadh, Saudi Arabia.
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- Battiwalla, Minoo (författare)
- Sarah Cannon BMT Program, Nashville, TN USA.
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- Beitinjaneh, Amer M. (författare)
- Univ Miami, Miami, FL USA.
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- Chhabra, Saurabh (författare)
- Med Coll Wisconsin, Dept Med, Div Hematol Oncol, Milwaukee, WI 53226 USA.
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- Diaz, Miguel Angel (författare)
- Univ Nino Jesus, Dept Hematol Oncol, Hosp Infantil, Madrid, Spain.
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- Engles, Katie (författare)
- CW Bill Young Marrow Donor Program, Kensington, MD USA.
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- Frangoul, Haydar (författare)
- TriStar Centennial & Sarah Cannon, Childrens Hosp, Nashville, TN USA.
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- Ganguly, Siddhartha (författare)
- Univ Kansas Hlth Syst, Div Hematol Malignancy & Cellular Therapeut, Kansas City, KS USA.
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- Gergis, Usama (författare)
- Weill Cornell Med Coll, Dept Med Oncol, Hematol Malignancies & Bone Marrow Transplant, New York Presbyterian Hosp, New York, NY USA.
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- Kamani, Nayesh R. (författare)
- Childrens Natl Med Ctr, Washington, DC 20010 USA.
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- Kamble, Rammurti T. (författare)
- Baylor Coll Med, Ctr Cell & Gene Therapy, Div Hematol & Oncol, Houston, TX 77030 USA.
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- Kasow, Kimberly A. (författare)
- Univ N Carolina, Chapel Hill, NC 27515 USA.
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- Lazarus, Hillard M. (författare)
- Univ Hosp Cleveland, Seidman Canc Ctr, Med Ctr, Cleveland, OH 44106 USA.
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- Liesveld, Jane L. (författare)
- Univ Rochester, Strong Mem Hosp, Med Ctr, Rochester, NY 14642 USA.
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- Norkin, Maxim (författare)
- Shands HealthCare, Dept Med, Div Hematol & Oncol, Gainesville, FL USA.;Univ Florida, Gainesville, FL USA.
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- O' Donnell, Paul, V (författare)
- Massachusetts Gen Hosp, Edgartown, MA USA.
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- Olsson, Richard (författare)
- Uppsala universitet,Centrum för klinisk forskning i Sörmland (CKFD),Karolinska Inst, Dept Lab Med, Div Therapeut Immunol, Stockholm, Sweden.
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- Rossman, Susan N. (författare)
- Gulf Coast Marrow Donor Ctr, Houston, TX USA.
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- Savani, Bipin N. (författare)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Hematol Oncol, Nashville, TN USA.
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- Schears, Raquel (författare)
- Mayo Clin & Mayo Grad Sch Med, Dept Emergency Med, Rochester, MN USA.
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- Seo, Sachiko (författare)
- Dokkyo Med Univ, Mibu, Tochigi, Japan.
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- Solh, Melhem M. (författare)
- Northside Hosp, Blood & Marrow Transplant Program, Atlanta, GA USA.
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- Spitzer, Thomas (författare)
- Massachusetts Gen Hosp, Boston, MA 02114 USA.
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- Sugrue, Michele (författare)
- LifeSouth Community Blood Ctr, Gainesville, FL USA.
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- Yared, Jean A. (författare)
- Univ Maryland, Dept Med, Blood & Marrow Transplantat Program, Div Hematol Oncol,Greenebaum Canc Ctr, Baltimore, MD 21201 USA.
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- Linenberger, Michael (författare)
- Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA.
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- Schwartz, Joseph (författare)
- Columbia Univ, Dept Pathol & Cell Biol, Irving Med Ctr, New York, NY USA.
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- Pulsipher, Michael A. (författare)
- Childrens Hosp Los Angeles, Div Hematol Oncol & Blood & Marrow Transplantat, USC Keck Sch Med, Los Angeles, CA 90027 USA.
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- Shah, Nirali N. (författare)
- NCI, Pediat Oncol Branch, Ctr Canc Res, NIH, Bethesda, MD 20892 USA.
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- Switzer, Galen E. (författare)
- Univ Pittsburgh, Pittsburgh, PA USA.
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- Confer, Dennis L. (författare)
- CIBMTR Ctr Int Blood & Marrow Transplant Res, Natl Marrow Donor Program Be Match, Minneapolis, MN USA.;Be Match, Natl Marrow Donor Program, Minneapolis, MN USA.
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- Shaw, Bronwen E. (författare)
- Med Coll Wisconsin, Dept Med, CIBMTR Ctr Int Blood & Marrow Transplant Res, Milwaukee, WI 53226 USA.
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- Wingard, John R. (författare)
- Shands HealthCare, Dept Med, Div Hematol & Oncol, Gainesville, FL USA.;Univ Florida, Gainesville, FL USA.
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Shands HealthCare, Dept Med, Div Hematol & Oncol, Gainesville, FL USA;Univ Florida, Gainesville, FL USA. Mayo Clin, Div Hematol Oncol, Blood & Marrow Transplantat Program, Jacksonville, FL 32224 USA. (creator_code:org_t)
- 2020-04-30
- 2020
- Engelska.
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Ingår i: Bone Marrow Transplantation. - : SPRINGERNATURE. - 0268-3369 .- 1476-5365. ; 55:11, s. 2121-2131
- Relaterad länk:
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https://www.ncbi.nlm...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Pre-harvest autologous blood collection from bone marrow (BM) donors is performed to meet potential post-operative transfusion needs. This study examines the impact of autologous blood transfusion on BM donor's health and safety. The study included first-time unrelated BM donors from the United States whose BM harvest was facilitated by the National Marrow Donor Program (NMDP) centers between 2006 and 2017. Examination of 7024 BM donors revealed that 60% received at least one unit of autologous blood. The donors who received autologous blood were older, had lower hemoglobin pre-harvest, underwent longer duration of anesthesia, and higher volume BM harvest. Only donors who underwent high-volume BM harvest, defined as a BM harvest volume >27% of donor's blood volume, benefited from autologous transfusion. After a high-volume BM harvest, autologous blood transfusion was shown to decrease grade 2 to 4 collection-associated toxicities within 48 h of BM donation (p = 0.010) and shorten the time to donor-reported "complete" recovery from donation-associated symptoms (p < 0.001). Therefore, autologous transfusion could be avoided as support of marrow donation in the majority of unrelated BM donors and should be limited to cases where the planned BM harvest volume is expected to exceed 27% of donor's blood volume.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
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Farhadfar, Nosha
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Murthy, Hemant S ...
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Logan, Brent R.
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Sees, Jennifer A ...
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Mouhab, Ayas
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Battiwalla, Mino ...
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visa fler...
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Beitinjaneh, Ame ...
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Chhabra, Saurabh
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Diaz, Miguel Ang ...
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Engles, Katie
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Frangoul, Haydar
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Ganguly, Siddhar ...
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Gergis, Usama
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Kamani, Nayesh R ...
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Kamble, Rammurti ...
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Kasow, Kimberly ...
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Lazarus, Hillard ...
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Liesveld, Jane L ...
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Norkin, Maxim
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O' Donnell, Paul ...
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Olsson, Richard
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Rossman, Susan N ...
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Savani, Bipin N.
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Schears, Raquel
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Seo, Sachiko
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Solh, Melhem M.
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Spitzer, Thomas
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Sugrue, Michele
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Yared, Jean A.
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Linenberger, Mic ...
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Schwartz, Joseph
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Pulsipher, Micha ...
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Shah, Nirali N.
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Switzer, Galen E ...
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Confer, Dennis L ...
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Shaw, Bronwen E.
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Wingard, John R.
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Uppsala universitet
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Karolinska Institutet