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Community-based int...
Community-based intervention for prevention and management of chronic obstructive pulmonary disease in Nepal (COBIN-P trial) : study protocol for a cluster-randomized controlled trial
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- Adhikari, Tara Ballav (författare)
- Aarhus Univ, Sect Global Hlth, Dept Publ Hlth, Aarhus, Denmark.;Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal.
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- Neupane, Dinesh (författare)
- Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal.;Johns Hopkins Univ, Dept Epidemiol, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA.
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- Karki, Arjun (författare)
- HAMS Hosp, Dept Pulm Crit Care & Sleep Med, Kathmandu, Nepal.
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- Drews, Arne (författare)
- Nepalmed, Leipzig, Germany.
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- Cooper, Brendan (författare)
- Univ Hosp Birmingham, Lung Funct & Sleep, Birmingham, W Midlands, England.
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- Högman, Marieann (författare)
- Uppsala universitet,Lung- allergi- och sömnforskning
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- Sigsgaard, Torben (författare)
- Aarhus Univ, Sect Environm Occupat & Hlth, Dept Publ Hlth, Aarhus, Denmark.
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- Kallestrup, Per (författare)
- Aarhus Univ, Sect Global Hlth, Dept Publ Hlth, Aarhus, Denmark.
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Aarhus Univ, Sect Global Hlth, Dept Publ Hlth, Aarhus, Denmark;Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal. Nepal Dev Soc, COBIN Project, Bharatpur, Chitwan, Nepal.;Johns Hopkins Univ, Dept Epidemiol, Welch Ctr Prevent Epidemiol & Clin Res, Baltimore, MD USA. (creator_code:org_t)
- 2021-07-21
- 2021
- Engelska.
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Ingår i: Trials. - : BioMed Central (BMC). - 1745-6215. ; 22
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://trialsjourna...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Background: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide and the commonest of non-communicable diseases (NCDs) in Nepal. Risk factors like indoor and outdoor air pollution, a high prevalence of smoking, and the lack of awareness of COPD make it a serious public health concern. However, no attempt has been made in Nepal to estimate its burden and address the disease at the community level.Method: This study aims to evaluate the effect of a community-based health educational intervention administered by Female Community Health Volunteers (FCHVs) on the prevention and management of COPD. An open-label, two-group, community-based, cluster-randomized controlled trial will be implemented in the semi-urban area of Pokhara Metropolitan city (former Lekhnath Municipality) located in the Kaski district of Nepal. The estimated sample size of the intervention will be 1143. The unit of randomization is the ward (administrative unit) of the study area. The follow-up survey will be conducted immediately after 12months of FCHVs-led interventions. The difference in the rate of decline of forced expiratory volume in 1s (FEV1) and FEV1/FVC (forced vital capacity) ratio are the primary outcomes and the change in the proportion of modifiable risk factors of COPD, health-related quality of life scores, and change in knowledge of COPD will be secondary outcomes.Discussion: This study will estimate the burden of COPD, the magnitude of risk factors and generate evidence to mobilize community health workers for COPD prevention and management at the community level in Nepal.Trial registrationClinicalTrials.gov NCT03797768. Registered on January 9, 2019.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- COPD
- Community health workers
- Nepal
- Female Community Health Volunteers
- Cluster randomized controlled trial
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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