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Deep neural network...
Deep neural network-estimated electrocardiographic age as a mortality predictor
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- Lima, Emilly M. (författare)
- Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Horta Ribeiro, Antônio (författare)
- Uppsala universitet,Avdelningen för systemteknik,Artificiell intelligens,Univ Fed Minas Gerais, Dept Ciencia Comp, Belo Horizonte, MG, Brazil
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- Paixao, Gabriela M. M. (författare)
- Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Horta Ribeiro, Manoel (författare)
- Ecole Polytech Fed Lausanne, Lausanne, Switzerland
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- Pinto-Filho, Marcelo M. (författare)
- Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Gomes, Paulo R. (författare)
- Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Oliveira, Derick M. (författare)
- Univ Fed Minas Gerais, Dept Ciencia Comp, Belo Horizonte, MG, Brazil
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- Sabino, Ester C. (författare)
- Univ Sao Paulo, Inst Med Trop, Fac Med, Sao Paulo, Brazil
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- Duncan, Bruce B. (författare)
- Univ Fed Rio Grande do Sul, Programa Posgrad Epidemiol, Porto Alegre, RS, Brazil.;Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil
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- Giatti, Luana (författare)
- Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Barreto, Sandhi M. (författare)
- Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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- Meira Jr, Wagner (författare)
- Univ Fed Minas Gerais, Dept Ciencia Comp, Belo Horizonte, MG, Brazil
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- Schön, Thomas B., Professor, 1977- (författare)
- Uppsala universitet,Avdelningen för systemteknik,Artificiell intelligens
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- Ribeiro, Antonio Luiz P. (författare)
- Univ Fed Minas Gerais, Hosp Clin, Telehlth Ctr, Belo Horizonte, MG, Brazil; Univ Fed Minas Gerais, Fac Med, Belo Horizonte, MG, Brazil
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(creator_code:org_t)
- 2021-08-25
- 2021
- Engelska.
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Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 12:1
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://www.nature.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The electrocardiogram (ECG) is the most commonly used exam for the screening and evaluation of cardiovascular diseases. Here, the authors propose that the age predicted by artificial intelligence from the raw ECG tracing can be a measure of cardiovascular health and provide prognostic information. The electrocardiogram (ECG) is the most commonly used exam for the evaluation of cardiovascular diseases. Here we propose that the age predicted by artificial intelligence (AI) from the raw ECG (ECG-age) can be a measure of cardiovascular health. A deep neural network is trained to predict a patient's age from the 12-lead ECG in the CODE study cohort (n = 1,558,415 patients). On a 15% hold-out split, patients with ECG-age more than 8 years greater than the chronological age have a higher mortality rate (hazard ratio (HR) 1.79, p < 0.001), whereas those with ECG-age more than 8 years smaller, have a lower mortality rate (HR 0.78, p < 0.001). Similar results are obtained in the external cohorts ELSA-Brasil (n = 14,236) and SaMi-Trop (n = 1,631). Moreover, even for apparent normal ECGs, the predicted ECG-age gap from the chronological age remains a statistically significant risk predictor. These results show that the AI-enabled analysis of the ECG can add prognostic information.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Lima, Emilly M.
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Horta Ribeiro, A ...
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Paixao, Gabriela ...
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Horta Ribeiro, M ...
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Pinto-Filho, Mar ...
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Gomes, Paulo R.
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visa fler...
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Oliveira, Derick ...
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Sabino, Ester C.
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Duncan, Bruce B.
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Giatti, Luana
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Barreto, Sandhi ...
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Meira Jr, Wagner
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Schön, Thomas B. ...
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Ribeiro, Antonio ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
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Nature Communica ...
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Uppsala universitet