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Migraine as a risk ...
Migraine as a risk factor for mixed symptoms of peripartum depression and anxiety in late pregnancy : A prospective cohort study.
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- Welander, Nike Zoe (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi
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- Mwinyi, Jessica (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi,WoMHeR (Centre for Women’s Mental Health during the Reproductive Lifespan)
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- Asif, Sana, M.D, PhD student (författare)
- Uppsala universitet,Anestesiologi och intensivvård,Obstetrisk och reproduktiv hälsoforskning
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- Schiöth, Helgi Birgir (författare)
- Uppsala universitet,Schiöth: Funktionell farmakologi,Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 119991 Moscow, Russia
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- Skalkidou, Alkistis, 1977- (författare)
- Uppsala universitet,WoMHeR (Centre for Women’s Mental Health during the Reproductive Lifespan),Obstetrisk och reproduktiv hälsoforskning
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- Fransson, Emma, PhD, 1973- (författare)
- Karolinska Institutet,Uppsala universitet,Obstetrisk och reproduktiv hälsoforskning,WoMHeR (Centre for Women’s Mental Health during the Reproductive Lifespan),Centre for Translational Microbiome Research, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 77 Stockholm, Sweden
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(creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: Journal of Affective Disorders. - : Elsevier. - 0165-0327 .- 1573-2517. ; 295, s. 733-739
- Relaterad länk:
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: Migraine has been identified as a risk factor for peripartum depression. However, little is known about the contribution of anxiety to this association or potential changes throughout the peripartum period.METHODS: In a sample of 4,831 women from the Biology, Affect, Stress, Imaging and Cognition cohort in Sweden, participants were asked about history of migraine prior to pregnancy. The participants completed the Edinburgh Postnatal Depression Scale (EPDS) at gestational weeks 17 and 32 and postpartum week 6. Multinomial logistic regression analyses were used to assess associations between migraine and symptoms of depression, anxiety or mixed depression and anxiety, while adjusting for potential confounders.RESULTS: In crude estimates, migraine was associated with separate and mixed symptoms of depression and anxiety at most time points. After adjustments, migraine was associated with anxiety at week 17 (adjusted odds ratio: 1.69; 95% confidence interval: 1.11-2.54) and with mixed depression and anxiety at week 32 (adjusted odds ratio: 1.45; 95% confidence interval: 1.06-1.99). None of the other associations remained statistically significant after adjustments.LIMITATIONS: Migraine history was self-reported. Symptoms of depression and anxiety were based on the screening tool EPDS and not on clinical diagnoses.CONCLUSIONS: The results demonstrate that migraine may be a risk factor for anxiety in mid- pregnancy and mixed symptoms of peripartum depression and anxiety in late pregnancy. Inflammatory and hormonal factors may underlie the association between migraine, depression and anxiety across the peripartum period.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- Anxiety Disorders
- Depression
- postpartum
- Mental health
- Migraine Disorders
- Peripartum period
- Pregnancy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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