Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors: evidence-based recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group

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Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors : evidence-based recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group

van Atteveld, Jenneke E. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.

Mulder, Renee L. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.

van den Heuvel-Eibrink, Marry M. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.

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Hudson, Melissa M. (författare): St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA.;St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, 332 N Lauderdale St, Memphis, TN 38105 USA.

Kremer, Leontien C. M. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.

Skinner, Roderick (författare): Great North Childrens Hosp, Dept Paediat & Adolescent Haematol Oncol, Newcastle Upon Tyne, Tyne & Wear, England.;Newcastle Univ, Ctr Canc, Newcastle Upon Tyne, Tyne & Wear, England.

Wallace, W. Hamish (författare): Royal Hosp Sick Children, Dept Paediat Oncol, Edinburgh, Midlothian, Scotland.

Constine, Louis S. (författare): Univ Rochester, Med Ctr, Dept Radiat Oncol, Rochester, NY 14642 USA.;Univ Rochester, Med Ctr, Dept Pediat, Rochester, NY 14642 USA.

Higham, Claire E. (författare): Univ Manchester, Christie Hosp NHS Fdn Trust, Dept Endocrinol, Manchester, Lancs, England.;Manchester Acad Hlth Sci Ctr, Manchester, Lancs, England.

Kaste, Sue C. (författare): St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA.;St Jude Childrens Res Hosp, Dept Diagnost Imaging, 332 N Lauderdale St, Memphis, TN 38105 USA.

Niinimaki, Riitta (författare): Univ Oulu, Oulu Univ Hosp, Dept Children & Adolescents, Oulu, Finland.;Univ Oulu, PEDEGO Res Unit, Oulu, Finland.

Mostoufi-Moab, Sogol (författare): Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA.;Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA.

Alos, Nathalie (författare): Ctr Hosp Univ St Justine, Dept Pediat, Endocrinol Div, Montreal, PQ, Canada.

Fintini, Danilo (författare): Bambino Gesu Pediat Hosp, IRCSS, Univ Hosp Pediat Dept, Endocrinol Unit, Rome, Italy.

Templeton, Kimberly J. (författare): Univ Kansas, Med Ctr, Dept Orthopaed Surg, Kansas City, KS 66103 USA.

Ward, Leanne M. (författare): Univ Ottawa, Dept Pediat, Childrens Hosp Eastern Ontario, Ottawa, ON, Canada.

Frey, Eva (författare): St Anna Childrens Hosp, Dept Pediat Hematol & Oncol, Vienna, Austria.

Franceschi, Roberto (författare): Santa Chiara Hosp, Dept Pediat, Trento, Italy.

Pavasovic, Vesna (författare): Great Ormond St Hosp Sick Children, Dept Paediat Haematol & Oncol, London, England.

Karol, Seth E. (författare): St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA.

Amin, Nadia L. (författare): Leeds Childrens Hosp, Dept Paediat Haematol, Leeds, W Yorkshire, England.

Vrooman, Lynda M. (författare): Dana Farber Canc Inst, Boston, MA 02115 USA.;Boston Childrens Hosp, Boston, MA USA.

Harila-Saari, Arja H. (författare): Uppsala universitet,Barnneurologi/Barnonkologi

Demoor-Goldschmidt, Charlotte (författare): Paris Sud XI Univ, Paris Saday Univ, INSERM U1018,Gustave Roussy Canc Campus, Ctr Res Epidemiol & Populat Hlth,Canc & Radiat Gr, Villejuif, France.;CHU Angers, Dept Pediat Ontohematol, Angers, France.;Francois Baclesse Ctr, Dept Radiotherapy, Caen, France.

Murray, Robert D. (författare): St James Univ Hosp, Leeds Teaching Hosp NHS Trust, Dept Endocrinol, Leeds, W Yorkshire, England.

Bardi, Edit (författare): St Anna Childrens Hosp, Vienna, Austria.;Kepler Univ Klinikum, Dept Pediat & Adolescent Med, Linz, Austria.

Lequin, Maarten H. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.;Univ Med Ctr Utrecht, Dept Radiol, Utrecht, Netherlands.

Faienza, Maria Felicia (författare): Univ A Moro, Pediat Unit, Dept Biomed Sci & Human Oncol, Bari, Italy.

Zaikova, Olga (författare): Oslo Univ Hosp, Dept Orthopaed Surg, Oslo, Norway.

Berger, Claire (författare): Univ Hosp St Etienne, Dept Pediat Hematol & Oncol CHU Nord, St Priest En Jarez, France.;Univ Jean Monnet, 28U1059 Sainbiose, St Etienne, France.

Mora, Stefano (författare): IRCCS San Raffaele Sci Inst, Lab Pediat Endocrinol, Milan, Italy.;IRCCS San Raffaele Sci Inst, Pediat Bone Dens Serv, Milan, Italy.

Ness, Kirsten K. (författare): St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, 332 N Lauderdale St, Memphis, TN 38105 USA.

Neggers, Sebastian J. C. M. M. (författare): Erasmus MC, Dept Endocrinol, Rotterdam, Netherlands.

Pluijm, Saskia M. F. (författare): Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands.

Simmons, Jill H. (författare): Vanderbilt Univ, Med Ctr, Dept Pediat, Nashville, TN 37232 USA.

Di Iorgi, Natascia (författare): Univ Genoa, Dept Neurosci Rehabil Ophthalmol Genet Maternal &, Genoa, Italy.;IRCCS Ist Giannina Gaslini, Dept Pediat, Genoa, Italy.

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Princess Maxima Ctr Pediat Oncol, NL-3584 CS Utrecht, Netherlands St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA.;St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, 332 N Lauderdale St, Memphis, TN 38105 USA. (creator_code:org_t)

Elsevier, 2021
2021
Engelska.
Ingår i: The Lancet Diabetes and Endocrinology. - : Elsevier. - 2213-8587 .- 2213-8595. ; 9:9, s. 622-637

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Tidskriftsartikel (refereegranskat)

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Childhood, adolescent, and young adult cancer survivors are at increased risk of reduced bone mineral density. Clinical practice surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could improve bone mineral density parameters and prevent fragility fractures. Discordances across current late effects guidelines necessitated international harmonisation of recommendations for bone mineral density surveillance. The International Late Effects of Childhood Cancer Guideline Harmonization Group therefore established a panel of 36 experts from ten countries, representing a range of relevant medical specialties. The evidence of risk factors for very low and low bone mineral density and fractures, surveillance modality, timing of bone mineral density surveillance, and treatment of very low and low bone mineral density were evaluated and critically appraised, and harmonised recommendations for childhood, adolescent, and young adult cancer survivors were formulated. We graded the recommendations based on the quality of evidence and balance between potential benefits and harms. Bone mineral density surveillance is recommended for survivors treated with cranial or craniospinal radiotherapy and is reasonable for survivors treated with total body irradiation. Due to insufficient evidence, no recommendation can be formulated for or against bone mineral density surveillance for survivors treated with corticosteroids. This surveillance decision should be made by the survivor and health-care provider together, after careful consideration of the potential harms and benefits and additional risk factors. We recommend to carry out bone mineral density surveillance using dualenergy x-ray absorptiometry at entry into long-term follow-up, and if normal (Z-score > -1), repeat when the survivor is aged 25 years. Between these measurements and thereafter, surveillance should be done as clinically indicated. These recommendations facilitate evidence-based care for childhood, adolescent, and young adult cancer survivors internationally.

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Cancer och onkol ...

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Bone mineral density surveillance for childhood, adolescent, and young adult cancer survivors : evidence-based recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group

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