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A Retrospective Cross-Sectional Study Assessing Self-Reported Adverse Events following Immunization (AEFI) of the COVID-19 Vaccine in Bangladesh

Sultana, Arifa (författare)
Univ Dhaka, Dept Pharm, Fac Pharm, Dhaka 1000, Bangladesh.
Shahriar, Saimon (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Tahsin, Md. Rafat (författare)
North South Univ, Dept Pharmaceut Sci, Plot 15,Block B,Bashundhara R-A, Dhaka 1229, Bangladesh.
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Mim, Sabiha Rahman (författare)
Uppsala universitet,Institutionen för farmaceutisk biovetenskap
Fatema, Kazi Rubiya (författare)
North South Univ, Dept Pharmaceut Sci, Plot 15,Block B,Bashundhara R-A, Dhaka 1229, Bangladesh.
Saha, Ananya (författare)
Univ Dhaka, Dept Pharm, Fac Pharm, Dhaka 1000, Bangladesh.
Yesmin, Fahmida (författare)
Univ Dhaka, Dept Pharm, Fac Pharm, Dhaka 1000, Bangladesh.
Bahar, Nasiba Binte (författare)
Univ Dhaka, Dept Pharm, Fac Pharm, Dhaka 1000, Bangladesh.
Samodder, Mithun (författare)
State Univ Bangladesh, Dept Pharm, 77 Satmasjid Rd, Dhaka 1205, Bangladesh.
Mamun, Md. Ariful Haque (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Aknur Rahman, Md. (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Ferdousy, Sonia (författare)
Atish Dipankar Univ Sci & Technol, Dept Pharm, Dhaka 1230, Bangladesh.
Akter, Tahmina (författare)
Dhaka Med Coll, Dept Physiol, Dhaka 1000, Bangladesh.
Aktar, Fahima (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Kuddus, Md. Ruhul (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Rahman, Md. Mustafizur (författare)
Khulna Univ, Sch Life Sci, Pharm Discipline, Khulna 9208, Bangladesh.
Sarker, Md. Moklesur Rahman (författare)
State Univ Bangladesh, Dept Pharm, 77 Satmasjid Rd, Dhaka 1205, Bangladesh.
Buyuker, Sultan Mehtap (författare)
Uskudar Univ, Dept Pharm Serv, TR-34662 Istanbul, Turkey.
Chowdhury, Jakir Ahmed (författare)
Univ Dhaka, Dept Pharmaceut Technol, Fac Pharm, Dhaka 1000, Bangladesh.
Chowdhury, Abu Asad (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Kabir, Shaila (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
Hossain, Md. Akter (författare)
Directorate Gen Drug Adm, Dhaka 1212, Bangladesh.
Amran, Md. Shah (författare)
Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh.
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Univ Dhaka, Dept Pharm, Fac Pharm, Dhaka 1000, Bangladesh Univ Dhaka, Dept Pharmaceut Chem, Mol Pharmacol & Herbal Drug Res Lab, Fac Pharm, Dhaka 1000, Bangladesh. (creator_code:org_t)
2021-09-28
2021
Engelska.
Ingår i: Vaccines. - : MDPI. - 2076-393X. ; 9:10
Relaterad länk:
https://doi.org/10.3...
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https://uu.diva-port... (primary) (Raw object)
https://www.mdpi.com...
https://urn.kb.se/re...
https://doi.org/10.3...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Background: The Oxford-AstraZeneca vaccine (Covishield) was the first to be introduced in Bangladesh to fight the ongoing global COVID-19 pandemic. As this vaccine had shown some side-effects in its clinical trial, we aimed to conduct a study assessing short-term adverse events following immunization (AEFIs) in Bangladesh. Method: A cross-sectional study was conducted on social and electronic media platforms by delivering an online questionnaire among people who had taken at least one dose of the COVID-19 vaccine. The collected data were then analysed to evaluate various parameters related to the AEFIs of the respondents. Results: A total of 626 responses were collected. Of these, 623 were selected based on complete answers and used for the analysis. Most of the respondents were between 30-60 years of age, and 40.4% were female. We found that a total of 8.5% of the total respondents had been infected with the SARS-CoV-2 virus. Our survey revealed that out of 623 volunteers, 317 reported various side-effects after taking the vaccine, which is about 50.88% of the total participants. The majority of participants (37.07%, 231/623) reported swelling and pain at the injection site and fever (25.84%, 162/623); these were some of the common localized and generalized symptoms after the COVID-19 vaccine administration. Conclusion: The side-effects reported after receiving the Oxford-AstraZeneca vaccine (Covishield) are similar to those reported in clinical trials, demonstrating that the vaccines have a safe therapeutic window. Moreover, further research is needed to determine the efficacy of existing vaccines in preventing SARS-CoV-2 infections or after-infection hospitalization.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

pharmacovigilance
side-effects
SARS-CoV-2
adverse events following immunization
vaccines
cross-sectional study

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  • Vaccines (Sök värdpublikationen i LIBRIS)

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