Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning: A systematic review

Bürger, ZoeUniv Tubingen, Tubingen Ctr Mental Hlth TuCMH, Dept Psychiat & Psychotherapy, Innovat Neuroimaging, Calwerstr 14, D-72076 Tubingen, Germany. (författare)

Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning : A systematic review

Levonorgestrel-intrauterine-devices (LNG-IUD) are one of the most used contraceptive methods worldwide. While several reviews exist on how LNG-IUDs impact physiology and gynaecological functions, this systematic review focuses on stress, mental health, quality of life, sexual functioning, and effects on brain architecture. While data on stress is scarce, results on mental health are ambiguous. More consistently, LNG-IUD use seems to improve quality of life and sexual functioning. No studies highlighting the consequences of LNG-IUD use on the brain were found. The reviewed studies are characterized by a substantial variation in approaches, participant groups, and study quality. More high-quality research assessing the effects of LNG-IUD on mental health, including response to stressors and brain function and structure, is needed to identify women vulnerable to adverse effects of LNG-IUD, also in comparison to oral contraceptives, and to empower women to make more informed choices concerning hormonal contraception.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reproduktionsmedicin och gynekologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Obstetrics, Gynaecology and Reproductive Medicine hsv//eng
Levonorgestrel intrauterine device
LNG-IUD
Hormonal contraception
Progestin
Mental health
Depression
Stress reactivity
Quality of life
Sexual functioning

Bucher, Anna MagdalenaUniv Tubingen, Tubingen Ctr Mental Hlth TuCMH, Dept Psychiat & Psychotherapy, Innovat Neuroimaging, Calwerstr 14, D-72076 Tubingen, Germany. (författare)
Comasco, Erika,1982-Uppsala universitet,Science for Life Laboratory, SciLifeLab,Comasco: Neuropsykofarmakologi(Swepub:uu)erico267 (författare)
Henes, MelanieUniv Tubingen, Dept Womens Hlth, Calwerstr 7, D-72076 Tubingen, Germany. (författare)
Hübner, StephanieUniv Tubingen, Dept Womens Hlth, Calwerstr 7, D-72076 Tubingen, Germany. (författare)
Kogler, LydiaUniv Tubingen, Tubingen Ctr Mental Hlth TuCMH, Dept Psychiat & Psychotherapy, Innovat Neuroimaging, Calwerstr 14, D-72076 Tubingen, Germany. (författare)
Derntl, BirgitUniv Tubingen, Tubingen Ctr Mental Hlth TuCMH, Dept Psychiat & Psychotherapy, Innovat Neuroimaging, Calwerstr 14, D-72076 Tubingen, Germany.;Univ Tubingen, Werner Reichardt Ctr Integrat Neurosci, Otfried Muller Str 25, D-72076 Tubingen, Germany.;Univ Tubingen, LEAD Grad Sch & Res Network, Tubingen, Germany. (författare)
Univ Tubingen, Tubingen Ctr Mental Hlth TuCMH, Dept Psychiat & Psychotherapy, Innovat Neuroimaging, Calwerstr 14, D-72076 Tubingen, Germany.Science for Life Laboratory, SciLifeLab (creator_code:org_t)

Ingår i:Frontiers in Neuroendocrinology: Frontiers Media S.A.630091-30221095-6808

Av författaren/redakt...: Bürger, Zoe; Bucher, Anna Mag ...; Comasco, Erika, ...; Henes, Melanie; Hübner, Stephani ...; Kogler, Lydia; visa fler...; Derntl, Birgit; visa färre...

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